SCHEMBL3273301

SCHEMBL3273301

NCc1c(F)c(F)c(F)c(F)c1CN

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 1/20 0.33
SLC6A4 P31645 1/20 0.33
SLC6A3 Q01959 1/20 0.33
LOXL2 Q9Y4K0 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL554229 0.92 SLC6A2 (0.33) SLC6A2SLC6A4SLC6A3LOXL2
SCHEMBL545418 0.88 LOXL2 (0.33) SLC6A2SLC6A4SLC6A3LOXL2
Hydrochloric Acid SCHEMBL3673293 0.85 LOXL2 (0.32) LOXL2
Sulfuric Acid SCHEMBL10981400 0.83 CA1 (0.36)
Butane SCHEMBL29002037 0.81
Butane SCHEMBL29002033 0.78 AOC3 (0.31)
SCHEMBL1809934 0.74
SCHEMBL16182175 0.74
Sulfuric Acid SCHEMBL9809084 0.72 CA5A (0.33)
SCHEMBL4949396 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1458792-B1 FLUORINATED POLYIMIDES SHOWA DENKO KK (JP) 2010-06-16 EP claimed
EP-1458792-B1 FLUORINATED POLYIMIDES SHOWA DENKO KK (JP) 2010-06-16 EP disclosed
EP-1299343-B1 PRODUCTION METHOD FOR BENZENEDIMETHANOL COMPOUND SHOWA DENKO KK (JP) 2009-01-14 EP disclosed
CN-1313515-C fluorinated polymers SHOWA DENKO KK (JP) 2007-05-02 CN disclosed
US-7112647-B2 Fluorinated polymer SHOWA DENKO K.K. (JP) 2006-09-26 US disclosed
US-7112647-B2 Fluorinated polymer SHOWA DENKO K.K. (JP) 2006-09-26 US disclosed
US-6909023-B2 Production method for benzenedimethanol compound SHOWA DENKO K.K. (JP) 2005-06-21 US disclosed
CN-1608096-A fluorinated polymers SHOWA DENKO KK (JP) 2005-04-20 CN disclosed
US-20050080230-A1 good heat resistance, excellent water repellency, excellent optical characteristics, and particularly superior transparency in a wavelength range from visible to near infrared SHOWA DENKO K.K. (JP) 2005-04-14 US disclosed
US-20050080230-A1 good heat resistance, excellent water repellency, excellent optical characteristics, and particularly superior transparency in a wavelength range from visible to near infrared SHOWA DENKO K.K. (JP) 2005-04-14 US disclosed
EP-1458792-A1 FLUORINATED POLYMER Showa Denko K.K. (JP) 2004-09-22 EP disclosed
US-20030171626-A1 Production method for benzenedimethanol compound SHOWA DENKO K.K. (JP) 2003-09-11 US disclosed
JP-2003252945-A FLUORINATED POLYMER SHOWA DENKO KK 2003-09-10 JP disclosed
WO-2003055936-A1 FLUORINATED POLYMER SHOWA DENKO K.K. (JP) 2003-07-10 WO disclosed
WO-2003055936-A1 FLUORINATED POLYMER SHOWA DENKO K.K. (JP) 2003-07-10 WO disclosed
EP-1299343-A1 PRODUCTION METHOD FOR BENZENEDIMETHANOL COMPOUND Showa Denko K.K. (JP) 2003-04-09 EP disclosed
WO-2002002504-A1 PRODUCTION METHOD FOR BENZENEDIMETHANOL COMPOUND SHOWA DENKO K.K. (JP) 2002-01-10 WO disclosed
US-4734486-A Polyamide comprising fluorinated xylyene moieties ICI AMERICAS INC. (US) 1988-03-29 US disclosed
EP-0099622-B1 PROCESS FOR THE HYDROGENATION OF PERHALOGENATED TEREPHTHALONITRILES TO AMINES, 2,3,5,6-TETRAFLUOROXYLYLENE DIAMINE AND SALTS THEREOF IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1985-12-04 EP disclosed
EP-0099622-A1 Process for the hydrogenation of perhalogenated terephthalonitriles to amines, 2,3,5,6-tetrafluoroxylylene diamine and salts thereof IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1984-02-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030171626-A1 Production method for benzenedimethanol compound NNMT, HNMT, GNMT SLC6A2 2062/4885SLC6A4 804/4885SLC6A3 3365/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.