Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CKS1B | P61024 | 2/20 | 0.62 |
| ▸ | SKP1 | P63208 | 2/20 | 0.62 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.62 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.60 |
| ▸ | KIT | P10721 | 2/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.52 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.51 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.51 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.51 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.51 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.50 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.50 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.49 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.49 |
| ▸ | ITGAL | P20701 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3270107 | 0.89 | MAP4K4 (0.50) | CKS1BSKP1SKP2HRH4KIT | |
| SCHEMBL3269829 | 0.88 | CKS1B (0.52) | CKS1BSKP1SKP2HRH4KIT | |
| SCHEMBL30718193 | 0.85 | CKS1B (0.54) | CKS1BSKP1SKP2HRH4KIT | |
| SCHEMBL27029576 | 0.85 | CKS1B (0.54) | CKS1BSKP1SKP2HRH4KIT | |
| SCHEMBL3268033 | 0.84 | SMARCA2 (0.53) | CKS1BSKP1SKP2KITMAP4K4 | |
| SCHEMBL3443191 | 0.82 | CKS1B (0.64) | CKS1BSKP1SKP2KITMAP4K4 | |
| SCHEMBL2386105 | 0.82 | GBA1 (0.54) | CKS1BSKP1SKP2KITMAP4K4 | |
| SCHEMBL8515152 | 0.82 | GPR119 (0.48) | CKS1BSKP1SKP2KITMAP4K4 | |
| SCHEMBL27927181 | 0.82 | HRH4 (0.61) | CKS1BSKP1SKP2HRH4KIT | |
| SCHEMBL3268748 | 0.81 | CKS1B (0.56) | CKS1BSKP1SKP2KITGPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101981010-A | Amide compound | TAKEDA PHARMACEUTICAL | 2011-02-23 | — | — | CN | disclosed |
| US-20100234389-A1 | AMIDE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-09-16 | — | — | US | disclosed |
| EP-2199282-A1 | AMIDE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2010-06-23 | — | — | EP | disclosed |
| US-20090163508-A1 | AMIDE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-06-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100234389-A1 | AMIDE COMPOUND | FAAH, FAAH2, NAAA | CKS1B 3175/4885SKP1 3469/4885SKP2 3535/4885 |
| US-20090163508-A1 | AMIDE COMPOUND | FAAH, FAAH2, NAAA | CKS1B 3175/4885SKP1 3469/4885SKP2 3535/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.