Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.61 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.51 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | PIM1 | P11309 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 5/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.42 |
| ▸ | ACP1 | P24666 | 2/20 | 0.42 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3277107 | 1.00 | AMY1A (0.61) | AMY1AALOX5NLRP3MEN1KMT2A | |
| SCHEMBL5462391 | 0.78 | NLRP3 (0.62) | NLRP3PIM1PPARGPTPN1ACP1 | |
| SCHEMBL5462396 | 0.78 | NLRP3 (0.62) | NLRP3PIM1PPARGPTPN1ACP1 | |
| SCHEMBL5461873 | 0.77 | MEN1 (0.57) | ALOX5NLRP3MEN1KMT2APOLB | |
| SCHEMBL5461877 | 0.77 | MEN1 (0.57) | ALOX5NLRP3MEN1KMT2APOLB | |
| SCHEMBL5463951 | 0.76 | PIM1 (0.58) | NLRP3MEN1KMT2APOLBPIM1 | |
| SCHEMBL5463955 | 0.76 | PIM1 (0.58) | NLRP3MEN1KMT2APOLBPIM1 | |
| SCHEMBL5787551 | 0.75 | NLRP3 (0.64) | AMY1AALOX5NLRP3MEN1KMT2A | |
| SCHEMBL5787549 | 0.75 | NLRP3 (0.64) | AMY1AALOX5NLRP3MEN1KMT2A | |
| SCHEMBL5460280 | 0.74 | MEN1 (0.60) | AMY1AALOX5NLRP3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7700655-B2 | Antiallergic agents | INSTITUTE OF MEDICINAL MOLECULAR DESIGN, INC. (JP) | 2010-04-20 | — | — | US | disclosed |
| US-20080090779-A1 | ANTIALLERGIC AGENTS | INSTITUTE OF MEDICINAL MOLECULAR DESIGN, INC. (JP) | 2008-04-17 | — | — | US | disclosed |
| US-20070185059-A1 | Antiallergic agents | INSTITUTE OF MEDICINAL MOLECULAR DESIGN, INC. (JP) | 2007-08-09 | — | — | US | disclosed |
| US-20070185110-A1 | Antiallergic agents | INSTITUTE OF MEDICINAL MOLECULAR DESIGN, INC. (JP) | 2007-08-09 | — | — | US | disclosed |
| US-20060122243-A1 | Antiallergic | INSTITUTE OF MEDICINAL MOLECULAR DESIGN, INC. (JP) | 2006-06-08 | — | — | US | disclosed |
| US-20060100257-A1 | Inhibitors against the activation of ap-1 and nfat | INSTITUTE OF MEDICINAL MOLECULAR DESIGN, INC. (JP) | 2006-05-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080090779-A1 | ANTIALLERGIC AGENTS | NAT1, EPX, HRH2 | AMY1A 133/4885ALOX5 246/4885NLRP3 305/4885 |
| US-20060122243-A1 | Antiallergic | EPX, NAT1, HNMT | AMY1A 176/4885ALOX5 281/4885NLRP3 488/4885 |
| US-20060100257-A1 | Inhibitors against the activation of ap-1 and nfat | NFATC1, AP1G1, ATF1 | AMY1A 1321/4885ALOX5 1913/4885NLRP3 932/4885 |
| US-20070185110-A1 | Antiallergic agents | NAT1, EPX, AHR | AMY1A 100/4885ALOX5 298/4885NLRP3 295/4885 |
| US-20070185059-A1 | Antiallergic agents | NAT1, EPX, AHR | AMY1A 111/4885ALOX5 316/4885NLRP3 276/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.