Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | BMP1 | P13497 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 2/20 | 0.36 |
| ▸ | MMP9 | P14780 | 2/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6864692 | 0.93 | MMP3 (0.50) | MMP3ALDH1A1MAPTBMP1LMNA | |
| SCHEMBL328400 | 0.86 | MMP3 (0.51) | MMP3ALDH1A1MAPTBMP1LMNA | |
| SCHEMBL10066483 | 0.83 | MMP3 (0.41) | MMP3ALDH1A1KEAP1NFE2L2MAPT | |
| SCHEMBL328554 | 0.83 | MMP3 (0.48) | MMP3ALDH1A1MAPTBMP1LMNA | |
| SCHEMBL328412 | 0.83 | MMP3 (0.37) | MMP3KEAP1NFE2L2HPGDMMP2 | |
| SCHEMBL6850229 | 0.81 | ALDH1A1 (0.39) | MMP3ALDH1A1MAPTBMP1LMNA | |
| SCHEMBL328403 | 0.81 | MEN1 (0.40) | MMP3ALDH1A1MAPTBMP1LMNA | |
| SCHEMBL6852594 | 0.81 | AHCY (0.44) | MMP3ALDH1A1CA9 | |
| SCHEMBL6852266 | 0.80 | HRH3 (0.36) | L3MBTL1MMP2MMP9MMP13 | |
| SCHEMBL328480 | 0.80 | MMP3 (0.47) | MMP3ALDH1A1MAPTBMP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2428509-A1 | Human adam-10 inhibitors | Symphony Evolution, Inc. (US) | 2012-03-14 | — | — | EP | disclosed |