Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | DAGLA | Q9Y4D2 | 3/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | F10 | P00742 | 1/20 | 0.32 |
| ▸ | STAT3 | P40763 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CASP6 | P55212 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL328661 | 0.86 | KMT2A (0.38) | KMT2ARAB9ADAGLAPOLBCYP3A4 | |
| SCHEMBL6851659 | 0.86 | CSF1R (0.33) | KMT2ADAGLAPGRPOLBMEN1 | |
| SCHEMBL328414 | 0.84 | DAGLA (0.37) | KMT2ADAGLAPGRPOLBCYP3A4 | |
| SCHEMBL328548 | 0.83 | DAGLA (0.37) | KMT2ADAGLAPGRMAPTPOLB | |
| SCHEMBL328544 | 0.82 | DAGLA (0.35) | KMT2ADAGLAPOLBCYP3A4CYP2C19 | |
| SCHEMBL6850664 | 0.79 | DAGLA (0.43) | DAGLAPGRPOLBALDH1A1 | |
| SCHEMBL6850484 | 0.79 | DAGLA (0.36) | KMT2ADAGLAPOLBCYP3A4CYP2C19 | |
| SCHEMBL6850244 | 0.78 | EDNRA (0.39) | DAGLACYP2C19HTT | |
| SCHEMBL10066710 | 0.77 | LSS (0.41) | KMT2ADAGLAMEN1ALDH1A1 | |
| SCHEMBL6852280 | 0.77 | BDKRB1 (0.40) | KMT2ADAGLAMEN1TP53ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2428509-A1 | Human adam-10 inhibitors | Symphony Evolution, Inc. (US) | 2012-03-14 | — | — | EP | disclosed |