Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.38 |
| ▸ | NCOR2 | Q9Y618 | 3/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 3/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.35 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.35 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.34 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL328545 | 0.91 | HDAC6 (0.47) | EDNRACYP1A2CYP2C19HTTHIF1A | |
| SCHEMBL6851659 | 0.87 | CSF1R (0.33) | HTTL3MBTL1DAGLA | |
| SCHEMBL6851665 | 0.85 | P2RX7 (0.41) | ROCK2ROCK1 | |
| SCHEMBL328661 | 0.84 | KMT2A (0.38) | CYP2C19TDP1L3MBTL1DAGLA | |
| SCHEMBL328414 | 0.83 | DAGLA (0.37) | CYP2C19L3MBTL1DAGLAMMP2MMP9 | |
| SCHEMBL328548 | 0.82 | DAGLA (0.37) | CYP2C19L3MBTL1DAGLA | |
| SCHEMBL328544 | 0.80 | DAGLA (0.35) | CYP1A2CYP2C19L3MBTL1DAGLA | |
| SCHEMBL6850664 | 0.79 | DAGLA (0.43) | L3MBTL1DAGLAMAPK1MMP2MMP9 | |
| SCHEMBL6850484 | 0.78 | DAGLA (0.36) | CYP2C19TDP1L3MBTL1DAGLA | |
| SCHEMBL328643 | 0.78 | KMT2A (0.35) | CYP2C19HTTDAGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011011181-A1 | PHARMACOLOGICAL CHAPERONES FOR THE TREATMENT OF ALZHEIMER'S DISEASE | AMICUS THERAPEUTICS, INC. (US) | 2011-01-27 | — | — | WO | disclosed |