Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 9/20 | 0.40 |
| ▸ | FLT3 | P36888 | 3/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.37 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 2/20 | 0.35 |
| ▸ | MMP8 | P22894 | 2/20 | 0.35 |
| ▸ | MMP13 | P45452 | 2/20 | 0.35 |
| ▸ | MMP7 | P09237 | 1/20 | 0.35 |
| ▸ | MMP12 | P39900 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | MMP14 | P50281 | 1/20 | 0.35 |
| ▸ | MMP16 | P51512 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6851665 | 0.91 | P2RX7 (0.41) | P2RX7FLT3SCN9AROCK1ROCK2 | |
| SCHEMBL328654 | 0.88 | MMP3 (0.36) | MMP3MMP1MMP8MMP13MMP7 | |
| SCHEMBL328545 | 0.85 | HDAC6 (0.47) | MMP3TDP1MMP1MMP8MMP13 | |
| SCHEMBL328494 | 0.84 | MMP13 (0.38) | MMP3TDP1MMP1MMP8MMP13 | |
| SCHEMBL6863163 | 0.82 | MMP1 (0.44) | MMP3MMP1MMP8MMP13MMP7 | |
| SCHEMBL328493 | 0.82 | TDP1 (0.44) | MMP3TDP1MMP1MMP8MMP13 | |
| SCHEMBL328649 | 0.81 | MMP1 (0.44) | MMP3MMP1MMP8MMP13MMP7 | |
| SCHEMBL6864397 | 0.80 | MMP1 (0.44) | MMP3MMP1MMP8MMP13MMP7 | |
| SCHEMBL6850285 | 0.80 | MMP13 (0.41) | MMP3TDP1MMP1MMP8MMP13 | |
| SCHEMBL6863154 | 0.79 | MMP1 (0.40) | MMP3TDP1MMP1MMP8MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2428509-A1 | Human adam-10 inhibitors | Symphony Evolution, Inc. (US) | 2012-03-14 | — | — | EP | disclosed |