Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 4/20 | 0.36 |
| ▸ | MMP13 | P45452 | 5/20 | 0.36 |
| ▸ | MMP2 | P08253 | 5/20 | 0.36 |
| ▸ | MMP9 | P14780 | 5/20 | 0.36 |
| ▸ | MMP1 | P03956 | 4/20 | 0.36 |
| ▸ | MMP8 | P22894 | 4/20 | 0.36 |
| ▸ | MMP7 | P09237 | 2/20 | 0.36 |
| ▸ | MMP12 | P39900 | 2/20 | 0.36 |
| ▸ | MMP14 | P50281 | 1/20 | 0.36 |
| ▸ | MMP16 | P51512 | 1/20 | 0.36 |
| ▸ | MEP1B | Q16820 | 3/20 | 0.35 |
| ▸ | BMP1 | P13497 | 2/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ADAM10 | O14672 | 1/20 | 0.33 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6851659 | 0.91 | CSF1R (0.33) | KMT2AALDH1A1 | |
| SCHEMBL328652 | 0.88 | P2RX7 (0.40) | MMP3MMP13MMP2MMP9MMP1 | |
| SCHEMBL328545 | 0.87 | HDAC6 (0.47) | MMP3MMP13MMP2MMP9MMP1 | |
| SCHEMBL6863163 | 0.82 | MMP1 (0.44) | MMP3MMP13MMP2MMP9MMP1 | |
| SCHEMBL328494 | 0.82 | MMP13 (0.38) | MMP3MMP13MMP2MMP9MMP1 | |
| SCHEMBL328649 | 0.82 | MMP1 (0.44) | MMP3MMP13MMP2MMP9MMP1 | |
| SCHEMBL6864397 | 0.81 | MMP1 (0.44) | MMP3MMP13MMP2MMP9MMP1 | |
| SCHEMBL6851665 | 0.79 | P2RX7 (0.41) | — | |
| SCHEMBL6864612 | 0.78 | BMP1 (0.42) | MMP3MMP13MMP2MMP9MMP1 | |
| SCHEMBL6850244 | 0.78 | EDNRA (0.39) | MMP3MMP13MMP2MMP9HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2428509-A1 | Human adam-10 inhibitors | Symphony Evolution, Inc. (US) | 2012-03-14 | — | — | EP | disclosed |