Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.33 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | TYR | P14679 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31653367 | 0.84 | EGFR (0.32) | EGFR | |
| SCHEMBL24216635 | 0.84 | HSD17B10 (0.38) | EGFRALDH1A1 | |
| SCHEMBL1620474 | 0.84 | ALDH5A1 (0.38) | EGFRALDH1A1KDM4EPTGS2RAB9A | |
| SCHEMBL577853 | 0.77 | ALDH1A1 (0.48) | CYP1A1CYP1B1ALDH1A1CYP2A6KDM4E | |
| SCHEMBL211753 | 0.76 | CYP1A1 (0.46) | CYP1A1CYP1B1 | |
| SCHEMBL92340 | 0.74 | CYP2A6 (0.46) | EGFRALDH1A1CYP2A6TYRKDM4E | |
| SCHEMBL2161087 | 0.74 | VCAM1 (0.38) | EGFRPTGS2 | |
| SCHEMBL1621200 | 0.72 | EGFR (0.33) | EGFR | |
| SCHEMBL308093 | 0.69 | ALDH1A1 (0.47) | ALDH1A1CYP2A6TYRKDM4EPTGS2 | |
| SCHEMBL2791843 | 0.69 | CYP1A1 (0.37) | CYP1A1CYP1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7022862-B2 | Scalable synthesis of dipyrromethanes | NORTH CAROLINA STATE UNIVERSITY (US) | 2006-04-04 | — | — | US | claimed |
| US-20050038262-A1 | aldehyde-pyrrole catalytic condensation leading to dipyrromethanes as a crystalline solid or as intermediates used for making porphyrin compounds; non-aqueous process | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2005-02-17 | — | — | US | claimed |
| US-11541122-B2 | Glucose sensitive insulins and uses thereof | ZIYLO LIMITED | 2023-01-03 | — | — | US | disclosed |
| US-11541122-B2 | Glucose sensitive insulins and uses thereof | ZIYLO LIMITED | 2023-01-03 | — | — | US | disclosed |
| US-20220047708-A1 | GLUCOSE SENSITIVE INSULINS AND USES THEREOF | NOVO NORDISK RESEARCH CENTRE OXFORD LIMITED (GB) | 2022-02-17 | — | — | US | disclosed |
| EP-3852873-A1 | GLUCOSE SENSITIVE INSULINS AND USES THEREOF | Ziylo Ltd (GB) | 2021-07-28 | — | — | EP | disclosed |
| CN-113164764-A | Glucose-sensitive insulin and use thereof | 兹洛有限公司 | 2021-07-23 | — | — | CN | disclosed |
| WO-2020058322-A1 | GLUCOSE SENSITIVE INSULINS AND USES THEREOF | ZIYLO LTD. (GB) | 2020-03-26 | — | — | WO | disclosed |
| US-7718794-B2 | Synthesis of porphyrins designed for attachment to electroactive surfaces via one or more carbon tethers | NORTH CAROLINA STATE UNIVERSITY (US) | 2010-05-18 | — | — | US | disclosed |
| US-20080194839-A1 | SYNTHESIS OF PORPHYRINS DESIGNED FOR ATTACHMENT TO ELECTROACTIVE SURFACES VIA ONE OR MORE CARBON TETHERS | NORTH CAROLINA STATE UNIVERSITY (US) | 2008-08-14 | — | — | US | disclosed |
| US-7378520-B2 | Synthesis of porphyrins designed for attachment to electroactive surfaces via one or more carbon tethers | NORTH CAROLINA STATE UNIVERSITY (US) | 2008-05-27 | — | — | US | disclosed |
| US-7022862-B2 | Scalable synthesis of dipyrromethanes | NORTH CAROLINA STATE UNIVERSITY (US) | 2006-04-04 | — | — | US | disclosed |
| US-20060009638-A1 | Synthesis of porphyrins designed for attachment to electroactive surfaces via one or more carbon tethers | ZETTACORE, INC. | 2006-01-12 | — | — | US | disclosed |
| US-6916982-B2 | Synthesis of perylene-porphyrin building blocks and polymers thereof for the production of light-harvesting arrays | NORTH CAROLINA STATE UNIVERSITY (US) | 2005-07-12 | — | — | US | disclosed |
| US-20050038262-A1 | aldehyde-pyrrole catalytic condensation leading to dipyrromethanes as a crystalline solid or as intermediates used for making porphyrin compounds; non-aqueous process | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2005-02-17 | — | — | US | disclosed |
| WO-2003105237-A1 | SYNTHESIS OF PERYLENE-PORPHYRIN BUILDING BLOCKS AND POLYMERS THEREOF FOR THE PRODUCTION OF LIGHT-HARVESTING ARRAYS | NORTH CAROLINA STATE UNIVERSITY (US) | 2003-12-18 | — | — | WO | disclosed |
| US-20030075216-A1 | Synthesis of perylene-porphyrin building blocks and polymers thereof for the production of light-harvesting arrays | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2003-04-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11541122-B2 | Glucose sensitive insulins and uses thereof | GPR119, IAPP, IRS1 | EGFR 1916/4885CYP1A1 2684/4885CYP1B1 2754/4885 |
| US-20060009638-A1 | Synthesis of porphyrins designed for attachment to electroactive surfaces via one or more carbon tethers | SCO2, PPOX, HCCS | EGFR 3514/4885CYP1A1 281/4885CYP1B1 752/4885 |
| US-20050038262-A1 | aldehyde-pyrrole catalytic condensation leading to dipyrromethanes as a crystalline solid or as intermediates used for making porphyrin compounds; non-aqueous process | PPOX, DAO, DDO | EGFR 4299/4885CYP1A1 606/4885CYP1B1 1276/4885 |
| US-20080194839-A1 | SYNTHESIS OF PORPHYRINS DESIGNED FOR ATTACHMENT TO ELECTROACTIVE SURFACES VIA ONE OR MORE CARBON TETHERS | SCO2, PPOX, HCCS | EGFR 3514/4885CYP1A1 281/4885CYP1B1 752/4885 |
| US-20220047708-A1 | GLUCOSE SENSITIVE INSULINS AND USES THEREOF | GPR119, IAPP, IRS1 | EGFR 1916/4885CYP1A1 2684/4885CYP1B1 2754/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.