SCHEMBL3288769

SCHEMBL3288769

Cc1ccc(C)c(OCl)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.46
TSHR P16473 2/20 0.44
TDP1 Q9NUW8 5/20 0.42
ALDH1A1 P00352 3/20 0.42
CYP2C9 P11712 2/20 0.42
LMNA P02545 1/20 0.42
HTT P42858 1/20 0.42
SMN1; SMN2 Q16637 3/20 0.40
KMT2A Q03164 1/20 0.40
CYP1A2 P05177 2/20 0.39
TTR P02766 1/20 0.39
CYP2C8 P10632 1/20 0.39
CHRM1 P11229 1/20 0.39
ADRA1A P35348 1/20 0.39
PPARG P37231 1/20 0.39
HTR2B P41595 1/20 0.39
PPARA Q07869 1/20 0.39
SLCO1B3 Q9NPD5 1/20 0.39
CISD1 Q9NZ45 1/20 0.39
SLCO1B1 Q9Y6L6 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16273815 0.80 ACHE (0.46) ACHETSHRTDP1ALDH1A1SMN1; SMN2
SCHEMBL3278966 0.79 ACHE (0.50) ACHETSHRTDP1ALDH1A1CYP2C9
SCHEMBL92174 0.77 ACHE (0.68) ACHETSHRTDP1ALDH1A1CYP2C9
SCHEMBL30167567 0.77 ACHE (0.68) ACHETSHRTDP1ALDH1A1CYP2C9
SCHEMBL17210758 0.76 TRPA1 (0.52) ACHETDP1ALDH1A1LMNAHTT
SCHEMBL13475540 0.76 CYP2C9 (0.47) ACHETSHRTDP1ALDH1A1CYP2C9
SCHEMBL28137086 0.76 MAOB (0.45) ACHETSHRALDH1A1HTTSMN1; SMN2
SCHEMBL7923034 0.75 ACHE (0.46) ACHETSHRTDP1ALDH1A1CYP2C9
SCHEMBL11681222 0.75 ALDH1A1 (0.48) ACHETSHRTDP1ALDH1A1CYP2C9
SCHEMBL14521443 0.75 ACHE (0.46) ACHETSHRTDP1ALDH1A1CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4734912-A2 HIGH SEPARATION DUAL PHASE EYE MAKE-UP REMOVER Mary Kay, Inc. (US) 2026-05-06 EP disclosed
WO-2026087386-A1 ROSIN DIESTER COMPOUNDS AND USES THEREOF FIRMENICH SA (CH) 2026-04-30 WO disclosed
US-20260090980-A1 COSMETIC COMPOSITIONS AND METHODS OF USING THE SAME MARY KAY INC. (US) 2026-04-02 US disclosed
US-20260083659-A1 SUNSCREEN COMPOSITIONS AND METHODS OF USE MARY KAY INC. (US) 2026-03-26 US disclosed
WO-2025264660-A1 COSMETIC COMPOSITION COMPRISING CAFFEINE AND MELATONIN MARY KAY INC. (US) 2025-12-26 WO disclosed
US-20250387310-A1 COMPOSITIONS THAT ENHANCE THE COOLING EFFECT FIRMENICH INCORPORATED (US) 2025-12-25 US disclosed
US-20250381117-A1 COSMETIC COMPOSITION COMPRISING CAFFEINE AND MELATONIN MARY KAY INC. (US) 2025-12-18 US disclosed
WO-2025202256-A1 COOLING COMPOSITION FIRMENICH SA (CH) 2025-10-02 WO disclosed
EP-4593967-A2 COSMETIC COMPOSITIONS AND METHODS OF USING THE SAME Mary Kay, Inc. (US) 2025-08-06 EP disclosed
EP-4583718-A1 FLAVONOID COMPOSITIONS AND USES THEREOF Firmenich SA (CH) 2025-07-16 EP disclosed
EP-1889850-B1 NOVEL TRITERPENIC ACID DERIVATIVE AND PREPARATION FOR EXTERNAL APPLICATION FOR SKIN COMPRISING THE SAME POLA CHEM IND INC (JP) 2014-03-05 EP disclosed
CN-101166510-B External preparation for skin SBI ALAPROMO CO LTD 2012-03-07 CN disclosed
US-20110060042-A1 EXTERNAL PREPARATION FOR SKIN SBI ALAPROMO CO., LTD. (JP) 2011-03-10 US disclosed
US-7718635-B2 Triterpenic acid derivative and preparation for external application for skin comprising the same POLA CHEMICAL INDUSTRIES INC. (JP) 2010-05-18 US disclosed
US-20090130227-A1 EXTERNAL PREPARATION FOR SKIN SBI ALAPROMO CO., LTD. (JP) 2009-05-21 US disclosed
US-20090075946-A1 NOVEL TRITERPENIC ACID DERIVATIVE AND PREPARATION FOR EXTERNAL APPLICATION FOR SKIN COMPRISING THE SAME POLA CHEMICAL INDUSTRIES INC. (JP) 2009-03-19 US disclosed
CN-101166510-A External preparation for skin COSMO OIL CO LTD (JP) 2008-04-23 CN disclosed
EP-1889850-A1 NOVEL TRITERPENIC ACID DERIVATIVE AND PREPARATION FOR EXTERNAL APPLICATION FOR SKIN COMPRISING THE SAME Pola Chemical Industries Inc. (JP) 2008-02-20 EP disclosed
EP-1878421-A1 EXTERNAL PREPARATION FOR SKIN COSMO OIL CO., LTD (JP) 2008-01-16 EP disclosed
US-3931340-A Chlorination of aromatic compounds ASAHI DENKA KOGYO K.K. (JA) 1976-01-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260090980-A1 COSMETIC COMPOSITIONS AND METHODS OF USING THE SAME CUTA, DSG1, HIRA ACHE 4/4885TSHR 3804/4885TDP1 1683/4885
US-20250387310-A1 COMPOSITIONS THAT ENHANCE THE COOLING EFFECT TAS2R30, TAS2R1, TAS2R20 ACHE 793/4885TSHR 4612/4885TDP1 922/4885
US-20090075946-A1 NOVEL TRITERPENIC ACID DERIVATIVE AND PREPARATION FOR EXTERNAL APPLICATION FOR SKIN COMPRISING THE SAME DUSP4, CUTA, DUSP22 ACHE 4433/4885TSHR 2815/4885TDP1 4392/4885
US-20260083659-A1 SUNSCREEN COMPOSITIONS AND METHODS OF USE CUTA, TYR, SUN2 ACHE 2999/4885TSHR 2955/4885TDP1 683/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.