SCHEMBL3290565

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5655974	0.83	NAAA (0.72)	MAPK1NAAACYP1A2CYP2C9CYP2C19
	SCHEMBL11038520	0.83	NAAA (0.72)	MAPK1NAAACYP1A2CYP2C9CYP2C19
	SCHEMBL3291433	0.83	POLB (0.61)	MAPK1ALDH1A1POLB
	SCHEMBL13293971	0.82	NAAA (0.52)	MAPK1NAAAAPPCYP1A2CYP2C9
	SCHEMBL446310	0.81	CDK1 (0.70)	MAPK1NAAACYP1A2CYP2C9CYP2C19
	SCHEMBL2158919	0.81	ALDH1A1 (0.64)	MAPK1NAAAAPPCYP1A2CYP2C9
	SCHEMBL2164508	0.81	NAAA (0.57)	MAPK1NAAAAPPCYP1A2CYP2C9
	SCHEMBL31661686	0.81	NAAA (0.57)	MAPK1NAAAAPPCYP1A2CYP2C9
	SCHEMBL30481047	0.81	MAPK1 (0.63)	MAPK1NAAACYP1A2CYP2C9CYP2C19
	SCHEMBL29036025	0.81	MAPK1 (0.63)	MAPK1NAAACYP1A2CYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.