Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | LTA4H | P09960 | 1/20 | 0.52 |
| ▸ | LAP3 | P28838 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | CTSB | P07858 | 1/20 | 0.49 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.47 |
| ▸ | ELANE | P08246 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | CTSS | P25774 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3913952 | 1.00 | ALDH1A1 (0.58) | ALDH1A1LTA4HLAP3TDP1MAPK1 | |
| SCHEMBL11821568 | 1.00 | ALDH1A1 (0.58) | ALDH1A1LTA4HLAP3TDP1MAPK1 | |
| SCHEMBL23342987 | 0.89 | ALDH1A1 (0.55) | ALDH1A1LTA4HLAP3TDP1MAPK1 | |
| SCHEMBL23342972 | 0.89 | ALDH1A1 (0.55) | ALDH1A1LTA4HLAP3TDP1MAPK1 | |
| SCHEMBL21843047 | 0.89 | ALDH1A1 (0.58) | ALDH1A1LTA4HLAP3TDP1MAPK1 | |
| SCHEMBL17384657 | 0.89 | ALDH1A1 (0.58) | ALDH1A1LTA4HLAP3TDP1MAPK1 | |
| SCHEMBL14066236 | 0.88 | ALDH1A1 (0.61) | ALDH1A1LTA4HLAP3TDP1MAPK1 | |
| SCHEMBL366832 | 0.88 | ALDH1A1 (0.61) | ALDH1A1LTA4HLAP3TDP1MAPK1 | |
| SCHEMBL1600361 | 0.88 | ALDH1A1 (0.61) | ALDH1A1LTA4HLAP3TDP1MAPK1 | |
| SCHEMBL6575848 | 0.88 | ALDH1A1 (0.61) | ALDH1A1LTA4HLAP3TDP1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4227310-A1 | CAMPTOTHECIN DERIVATIVE AND LIGAND-DRUG CONJUGATE THEREOF | Sichuan Baili Pharmaceutical Co. Ltd. (CN) | 2023-08-16 | — | — | EP | disclosed |
| CN-108473499-B | Novel pyrazolopyrimidine derivatives | 诺华股份有限公司 | 2021-07-23 | — | — | CN | disclosed |
| CN-106170489-B | New Pyrazolopyrimidine derivative and its purposes as MALT1 inhibitor | 诺华股份有限公司 | 2019-05-03 | — | — | CN | disclosed |
| EP-2407447-B1 | METHOD FOR PRODUCING OPTICALLY ACTIVE 2-HYDROXY ESTER | TOKYO UNIV OF SCIENCE EDUCATIONAL FOUNDATION ADMINISTRATIVE ORGANIZATION (JP) | 2018-04-18 | — | — | EP | disclosed |
| CN-106170489-A | New Pyrazolopyrimidine derivative and the purposes as MALT1 inhibitor thereof | 诺华股份有限公司 | 2016-11-30 | — | — | CN | disclosed |
| US-8552215-B2 | Method for producing optically active 2-hydroxy ester and novel intermediate compound | TOKYO UNIVERSITY OF SCIENCE EDUCATIONAL FOUNDATION ADMINISTRATIVE ORGANIZATION (JP) | 2013-10-08 | — | — | US | disclosed |
| US-8357662-B2 | Surface-based ammonium ion sensor and methods of making thereof | WORCESTER POLYTECHNIC INSTITUTE (US) | 2013-01-22 | — | — | US | disclosed |
| EP-2407447-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE 2-HYDROXY ESTER AND NOVEL INTERMEDIATE COMPOUND | Tokyo University Of Science Educational Foundation Administrative Organization (JP) | 2012-01-18 | — | — | EP | disclosed |
| US-20110319650-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE 2-HYDROXY ESTER AND NOVEL INTERMEDIATE COMPOUND | TOKYO UNIVERSITY OF SCIENCE EDUCATIONAL FOUNDATION ADMINISTRATIVE ORGANIZATION (JP) | 2011-12-29 | — | — | US | disclosed |
| US-20100290951-A1 | SURFACE-BASED AMMONIUM ION SENSOR: AN ELECTRODE DERIVATIZED WITH A SELF-ASSEMBLED MONOLAYER | WORCESTER POLYTECHNIC INSITUTE (US) | 2010-11-18 | — | — | US | disclosed |
| US-20020028803-A1 | Carbamate caspase inhibitors and uses thereof | VERTEX PHARMACEUTICALS INCORPORATED | 2002-03-07 | — | — | US | disclosed |
| WO-2001072707-A2 | CARBAMATE CASPASE INHIBITORS AND USES THEREOF | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2001-10-04 | — | — | WO | disclosed |
| US-6242514-B1 | CYCLIC PHOSPHATE OR PHOSPHONATE; HEAT AND OXIDATION STABILIZER ESPECIALLY FOR OLEFIN POLYMERS AND ENGINEERING THERMOPLASTICS | SUMITOMO CHEMICAL COMPANY, LTD. (JP) | 2001-06-05 | — | — | US | disclosed |
| US-5914361-A | IMPART HEAT STABILITY TO ORGANIC MATERIALS, INCLUDING POLYOLEFINS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1999-06-22 | — | — | US | disclosed |
| EP-0721945-B1 | BENZOLACTAM DERIVATIVE | SHIONOGI & CO (JP) | 1999-02-24 | — | — | EP | disclosed |
| US-5830936-A | THERMAL STABILIZERS FOR POLYOLEFINS AND ENGINEERING PLASTICS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1998-11-03 | — | — | US | disclosed |
| US-5652232-A | VIRICIDES, TREATMENT OF RETROVIRUS INFECTIOUS DISEASE; AIDS | SHIONOGI & CO., LTD. (JP) | 1997-07-29 | — | — | US | disclosed |
| EP-0721945-A1 | BENZOLACTAM DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 1996-07-17 | — | — | EP | disclosed |
| WO-1996011927-A1 | ENDOTHELIN ANTAGONISTS | ABBOTT LABORATORIES (US) | 1996-04-25 | — | — | WO | disclosed |
| US-5232624-A | Components of tilted smectic liquid-crystalline phases | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1993-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020028803-A1 | Carbamate caspase inhibitors and uses thereof | CASP1, CASP2, CASP3 | ALDH1A1 1692/4885LTA4H 1378/4885LAP3 1086/4885 |
| US-20100290951-A1 | SURFACE-BASED AMMONIUM ION SENSOR: AN ELECTRODE DERIVATIZED WITH A SELF-ASSEMBLED MONOLAYER | DNMT3A, ACMSD, CD4 | ALDH1A1 2016/4885LTA4H 4779/4885LAP3 2426/4885 |
| US-20110319650-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE 2-HYDROXY ESTER AND NOVEL INTERMEDIATE COMPOUND | CA7, HAO2, HACL2 | ALDH1A1 239/4885LTA4H 106/4885LAP3 650/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.