Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 5/20 | 0.41 |
| ▸ | CA1 | P00915 | 3/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL9457320 | 0.89 | CA2 (0.41) | TSHRCES2CES1CA2CA1 | |
| Trifluoromethanesulfonic Acid SCHEMBL8976229 | 0.82 | GPR3 (0.46) | CES2CES1CA2CA1PRSS1 | |
| SCHEMBL247179 | 0.81 | CALM1 (0.50) | TSHRSMN1; SMN2CES2CES1ALDH1A1 | |
| Iodide SCHEMBL10884305 | 0.78 | CALM1 (0.47) | TSHRSMN1; SMN2CES2CES1ALDH1A1 | |
| Bromide SCHEMBL10885367 | 0.78 | CALM1 (0.47) | TSHRSMN1; SMN2CES2CES1ALDH1A1 | |
| SCHEMBL9456819 | 0.77 | CYP3A4 (0.50) | TSHRALDH1A1LMNACYP3A4MAPT | |
| SCHEMBL11742977 | 0.76 | TSHR (0.54) | TSHRSMN1; SMN2CES2CES1KDM4E | |
| Sulfuric Acid SCHEMBL7171619 | 0.74 | CYP1A2 (0.43) | TSHRSMN1; SMN2CES2CES1KDM4E | |
| Sulfuric Acid SCHEMBL29490719 | 0.74 | CES2 (0.43) | TSHRSMN1; SMN2CES2CES1KDM4E | |
| SCHEMBL8973289 | 0.74 | CES1 (0.38) | TSHRCES2CES1ALDH1A1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7737244-B2 | Process for preparing polyarylate | LG CHEM, LTD. (KR) | 2010-06-15 | — | — | US | claimed |
| US-20090036634-A1 | Process for Preparing Polyarylate | SHANJIN OPTOELECTRONICS (SUZHOU) CO., LTD. (CN) | 2009-02-05 | — | — | US | claimed |
| WO-2007094638-A1 | PROCESS FOR PREPARING POLYARYLATE | LG CHEM, LTD. (KR) | 2007-08-23 | — | — | WO | claimed |
| US-7737244-B2 | Process for preparing polyarylate | LG CHEM, LTD. (KR) | 2010-06-15 | — | — | US | disclosed |
| US-20090036634-A1 | Process for Preparing Polyarylate | SHANJIN OPTOELECTRONICS (SUZHOU) CO., LTD. (CN) | 2009-02-05 | — | — | US | disclosed |
| WO-2007094638-A1 | PROCESS FOR PREPARING POLYARYLATE | LG CHEM, LTD. (KR) | 2007-08-23 | — | — | WO | disclosed |
| EP-0424314-B1 | Heat curable mixtures | CIBA GEIGY AG (CH) | 1994-12-07 | — | — | EP | disclosed |
| US-5247113-A | Curing agents or curing accelerators for epoxy resins | CIBA-GEIGY CORPORATION (US) | 1993-09-21 | — | — | US | disclosed |
| EP-0379464-B1 | ARALIPHATIC SULFONIUM SALTS AND THEIR USE | CIBA-GEIGY AG (CH) | 1993-02-10 | — | — | EP | disclosed |
| US-5149767-A | Epoxy compound or resin and polyisocyanate; high heat distortion point | CIBA-GEIGY CORPORATION (US) | 1992-09-22 | — | — | US | disclosed |
| US-5013814-A | Araliphatic sulfonium salts and their use | CIBA-GEIGY CORPORATION (US) | 1991-05-07 | — | — | US | disclosed |
| EP-0424314-A2 | Heat curable mixtures | CIBA-GEIGY AG (CH) | 1991-04-24 | — | — | EP | disclosed |
| EP-0379464-A1 | Araliphatic sulfonium salts and their use | CIBA-GEIGY AG (CH) | 1990-07-25 | — | — | EP | disclosed |
| EP-0053937-B1 | POLYNUCLEAR FUSED AROMATIC RING TYPE POLYMER AND PREPARATION THEREOF | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1985-06-19 | — | — | EP | disclosed |
| US-4463162-A | POLYESTERS FROM ANTHRACENEDIOL | ASAHI-DOW LIMITED (JP) | 1984-07-31 | — | — | US | disclosed |
| EP-0053937-A1 | Polynuclear fused aromatic ring type polymer and preparation thereof | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1982-06-16 | — | — | EP | disclosed |
| US-4066623-A | INVERSE INTERFACIAL POLYMERIZATION FOR PREPARING CERTAIN HALOGENATED AROMATIC POLYESTERS | CELANESE CORPORATION (US) | 1978-01-03 | — | — | US | disclosed |