SCHEMBL329946

SCHEMBL329946

Oc1ccc2c(c1)CNC2

nearest known ligand 0.69

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 5/20 0.46
DRD1 P21728 3/20 0.46
DRD4 P21917 2/20 0.43
PNMT P11086 2/20 0.42
DRD3 P35462 3/20 0.41
DRD5 P21918 2/20 0.41
CHRNB2 P17787 2/20 0.41
CHRNA4 P43681 2/20 0.41
OPRK1 P41145 1/20 0.39
PBRM1 Q86U86 1/20 0.39
HSD17B10 Q99714 1/20 0.39
ESR1 P03372 1/20 0.38
ESR2 Q92731 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30015222 1.00 DRD2 (0.46) DRD2DRD1DRD4PNMTDRD3
Bromide SCHEMBL383952 0.98 DRD2 (0.44) DRD2DRD1DRD4PNMTDRD3
Hydrochloric Acid SCHEMBL3772707 0.98 DRD2 (0.44) DRD2DRD1DRD4PNMTDRD3
SCHEMBL29514775 0.82 DRD2 (0.62) DRD2DRD1DRD4PNMTDRD3
SCHEMBL1017452 0.82 DRD2 (0.62) DRD2DRD1DRD4PNMTDRD3
SCHEMBL470826 0.82 PNMT (0.66) DRD2DRD1DRD4PNMTDRD3
Hydrochloric Acid SCHEMBL2675120 0.81 PNMT (0.63) DRD2DRD1DRD4PNMTDRD3
Hydrochloric Acid SCHEMBL31336072 0.81 DRD2 (0.61) DRD2DRD1DRD4PNMTDRD3
Bromide SCHEMBL587893 0.81 DRD2 (0.61) DRD2DRD1DRD4PNMTDRD3
Hydrochloric Acid SCHEMBL30955057 0.81 PNMT (0.63) DRD2DRD1DRD4PNMTDRD3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 148 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119930493-A (R) - (1- ([ 1,1' -biphenyl ] -4-yl) -3-hydroxypropyl-2-yl) carbamic acid tert-butyl ester intermediate and preparation method and application thereof 江苏科本药业有限公司 2025-05-06 CN claimed
CN-1013274-B Process for preparing cephalosporin derivatives BANYU PHARMA CO LTD (JP) 1991-07-24 CN claimed
CN-85109769-A The preparation of cephalosporins derivatives and application 1986-12-17 CN claimed
EP-0186187-A2 Cephalosporin derivatives BANYU PHARMACEUTICAL CO., LTD. (JP) 1986-07-02 EP claimed
CN-119930493-A (R) - (1- ([ 1,1' -biphenyl ] -4-yl) -3-hydroxypropyl-2-yl) carbamic acid tert-butyl ester intermediate and preparation method and application thereof 江苏科本药业有限公司 2025-05-06 CN disclosed
US-20240174631-A1 COMPOUNDS, COMPOSITIONS, AND METHODS FOR MODULATING FGF ACTIVITY RECOVERY THERAPEUTICS, INC. 2024-05-30 US disclosed
CN-114920911-B Method for producing polyisothiaindene conductive polymer 株式会社力森诺科 2024-05-03 CN disclosed
EP-4291177-A1 COMPOUNDS, COMPOSITIONS, AND METHODS FOR MODULATING FGF ACTIVITY Recovery Therapeutics, Inc. (US) 2023-12-20 EP disclosed
CN-117157069-A Compounds, compositions and methods for modulating FGF activity 康复治疗公司 2023-12-01 CN disclosed
EP-3623369-B1 NOVEL MORPHOLINYL AMINE COMPOUNDS FOR THE TREATMENT OF AUTOIMMUNE DISEASE HOFFMANN LA ROCHE (CH) 2023-10-25 EP disclosed
CN-116391129-A Target binding assays for RAS proteins 普罗美加公司 2023-07-04 CN disclosed
WO-2023070605-A1 METHODS OF PREPARING 6-MEMBERED AZA-HETEROCYCLIC CONTAINING DELTA-OPIOID RECEPTOR MODULATING COMPOUNDS TREVENA, INC. (US) 2023-05-04 WO disclosed
US-20040167119-A1 2-(aminomethyl) arylamide analgesics PHARMACOPEIA, INC (US) 2004-08-26 US disclosed
WO-2002062763-A2 INHIBITION OF RAF KINASE USING QUINOLYL ISOQUINOLYL OR PYRIDYL UREAS BAYER CORPORATION (US) 2002-08-15 WO disclosed
EP-1140840-A1 -G(V)-CARBOXYARYL SUBSTITUTED DIPHENYL UREAS AS RAF KINASE INHIBITORS Bayer Corporation (US) 2001-10-10 EP disclosed
WO-2000042012-A1 φ-CARBOXYARYL SUBSTITUTED DIPHENYL UREAS AS RAF KINASE INHIBITORS BAYER CORPORATION (US) 2000-07-20 WO disclosed
CN-1013274-B Process for preparing cephalosporin derivatives BANYU PHARMA CO LTD (JP) 1991-07-24 CN disclosed
US-4677100-A ANTIBIOTICS BANYU PHARMACEUTICAL CO., LTD. (JP) 1987-06-30 US disclosed
CN-85109769-A The preparation of cephalosporins derivatives and application 1986-12-17 CN disclosed
EP-0186187-A2 Cephalosporin derivatives BANYU PHARMACEUTICAL CO., LTD. (JP) 1986-07-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240174631-A1 COMPOUNDS, COMPOSITIONS, AND METHODS FOR MODULATING FGF ACTIVITY FGF1, FGF2, FGFR1 DRD2 4709/4885DRD1 4805/4885DRD4 4843/4885
US-20040167119-A1 2-(aminomethyl) arylamide analgesics OPRL1, OPRM1, OPRK1 DRD2 808/4885DRD1 1130/4885DRD4 1614/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.