Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.52 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
| ▸ | MMP8 | P22894 | 4/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3301635 | 1.00 | SLC6A2 (0.52) | SLC6A2TAAR1SMN1; SMN2HIF1AMAPT | |
| SCHEMBL3818366 | 0.83 | SMN1; SMN2 (0.55) | SLC6A2TAAR1SMN1; SMN2HIF1ACYP3A4 | |
| SCHEMBL3818364 | 0.83 | SMN1; SMN2 (0.55) | SLC6A2TAAR1SMN1; SMN2HIF1ACYP3A4 | |
| SCHEMBL8759 | 0.83 | SLC6A2 (0.56) | SLC6A2TAAR1SMN1; SMN2HIF1AMAPT | |
| SCHEMBL27829250 | 0.82 | SLC6A2 (0.54) | SLC6A2TAAR1SMN1; SMN2HIF1AMAPT | |
| Hydrochloric Acid SCHEMBL3136989 | 0.82 | SLC6A2 (0.54) | SLC6A2TAAR1SMN1; SMN2HIF1AMAPT | |
| SCHEMBL5320849 | 0.81 | MAPT (0.46) | SLC6A2SMN1; SMN2HIF1AMAPTKMT2A | |
| SCHEMBL1059557 | 0.80 | SLC6A2 (0.52) | SLC6A2TAAR1SMN1; SMN2HIF1AMAPT | |
| SCHEMBL5268840 | 0.80 | SLC6A2 (0.57) | SLC6A2TAAR1SMN1; SMN2HIF1AMAPT | |
| SCHEMBL407787 | 0.80 | SLC6A2 (0.57) | SLC6A2TAAR1SMN1; SMN2HIF1AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120283236-A1 | Porphyrin Catalysts and Methods of Use Thereof | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2012-11-08 | — | — | US | disclosed |
| US-8232267-B2 | Porphyrin catalysts and methods of use thereof | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2012-07-31 | — | — | US | disclosed |
| US-20100093688-A1 | Porphyrin catalysts and methods of use thereof | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2010-04-15 | — | — | US | disclosed |
| WO-2008094222-A2 | PORPHYRIN CATALYSTS AND METHODS OF USE THEREOF | TRUSTEES OF PRINCETON (US) | 2008-08-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120283236-A1 | Porphyrin Catalysts and Methods of Use Thereof | PPOX, POR, MPO | SLC6A2 684/4885TAAR1 3688/4885SMN1; SMN2 4130/4885 |
| US-20100093688-A1 | Porphyrin catalysts and methods of use thereof | PPOX, POR, MPO | SLC6A2 684/4885TAAR1 3688/4885SMN1; SMN2 4130/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.