Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.55 |
| ▸ | PPARG | P37231 | 1/20 | 0.51 |
| ▸ | PPARA | Q07869 | 1/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.46 |
| ▸ | MMP8 | P22894 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | FDPS | P14324 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3818366 | 1.00 | SMN1; SMN2 (0.55) | SMN1; SMN2HIF1APPARGPPARASLC6A2 | |
| SCHEMBL26664476 | 0.91 | BLM (0.52) | SMN1; SMN2HIF1APPARGPPARASLC6A2 | |
| SCHEMBL3301635 | 0.83 | SLC6A2 (0.52) | SMN1; SMN2HIF1APPARGPPARASLC6A2 | |
| SCHEMBL3301639 | 0.83 | SLC6A2 (0.52) | SMN1; SMN2HIF1APPARGPPARASLC6A2 | |
| SCHEMBL27792993 | 0.82 | PPARA (0.55) | PPARGPPARASLC6A2CYP3A4CYP2C9 | |
| SCHEMBL26664449 | 0.80 | BLM (0.43) | SMN1; SMN2HIF1APPARGPPARACYP3A4 | |
| SCHEMBL28294369 | 0.80 | MMP8 (0.50) | SMN1; SMN2HIF1APPARGPPARASLC6A2 | |
| SCHEMBL8710382 | 0.80 | SMN1; SMN2 (0.57) | SMN1; SMN2HIF1APPARGPPARASLC6A2 | |
| SCHEMBL27908890 | 0.80 | SMN1; SMN2 (0.57) | SMN1; SMN2HIF1APPARGPPARASLC6A2 | |
| SCHEMBL517462 | 0.80 | SMN1; SMN2 (0.57) | SMN1; SMN2HIF1APPARGPPARASLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107428092-B | Additive manufacturing method using photomodulated free radical polymerization | 陶氏环球技术有限责任公司 | 2021-06-08 | — | — | CN | claimed |
| EP-3271155-B1 | METHOD OF ADDITIVE MANUFACTURING USING PHOTOREGULATED RADICAL POLYMERIZATION | DOW GLOBAL TECHNOLOGIES LLC (US) | 2020-09-30 | — | — | EP | claimed |
| EP-2935495-B1 | PRESSURE-SENSITIVE ADHESIVES PREPARED FROM DEGRADABLE MONOMERS AND POLYMERS | 3M INNOVATIVE PROPERTIES CO (US) | 2019-10-09 | — | — | EP | disclosed |
| US-9334428-B2 | Pressure-sensitive adhesives prepared from degradable monomers and polymers | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2016-05-10 | — | — | US | disclosed |
| US-20150337179-A1 | PRESSURE-SENSITIVE ADHESIVES PREPARED FROM DEGRADABLE MONOMERS AND POLYMERS | 3M INNOVATIVE PROPERTIES COMPANY | 2015-11-26 | — | — | US | disclosed |
| EP-2935495-A1 | PRESSURE-SENSITIVE ADHESIVES PREPARED FROM DEGRADABLE MONOMERS AND POLYMERS | 3M Innovative Properties Company (US) | 2015-10-28 | — | — | EP | disclosed |
| WO-2014099300-A1 | PRESSURE-SENSITIVE ADHESIVES PREPARED FROM DEGRADABLE MONOMERS AND POLYMERS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2014-06-26 | — | — | WO | disclosed |
| EP-1483255-B1 | PROCESS FOR SYNTHESIZING CHIRAL N-ARYL PIPERAZINES | WYETH CORP (US) | 2009-08-12 | — | — | EP | disclosed |
| US-7091349-B2 | Process for synthesizing N-aryl piperazines with chiral N′-1-[benzoyl(2-pyridyl)amino]-2-propane substitution | WYETH (US) | 2006-08-15 | — | — | US | disclosed |
| EP-1675827-A1 | NOVEL METHOD FOR PREPARATION OF CRYSTALLINE PERINDOPRIL ERBUMINE | Lupin Limited (IN) | 2006-07-05 | — | — | EP | disclosed |
| EP-1603558-A1 | PROCESS FOR PREPARATION OF PERINDOPRIL AND SALTS THEREOF | Lupin Limited (IN) | 2005-12-14 | — | — | EP | disclosed |
| US-20030187265-A1 | Process for synthesizing N-aryl piperazines with chiral N'-1-[benzoyl(2-pyridyl)amino]-2-propane substitution | WYETH | 2003-10-02 | — | — | US | disclosed |
| WO-2003078417-A1 | PROCESS FOR SYNTHESIZING CHIRAL N-ARYL PIPERAZINES | WYETH, A CORPORATION OF THE STATE OF DELAWARE (US) | 2003-09-25 | — | — | WO | disclosed |
| EP-0789029-B1 | Improved procedure for the preparation of pure(S,S)-N-(1-Ethoxycarbonyl-3-phenylprophyl)-alanin). | DSM FINE CHEM AUSTRIA GMBH (AT) | 2003-09-10 | — | — | EP | disclosed |
| US-6201046-B1 | HALOGENATED ALKALI OR ALKALINE EARTH METAL SALT OF BRANCHED CARBOXYLIC ACIDS | ISP INVESTMENTS INC. | 2001-03-13 | — | — | US | disclosed |
| EP-0980239-A1 | COSMETIC SKIN CONDITIONING COMPOSITIONS | UNILEVER PLC (GB) | 2000-02-23 | — | — | EP | disclosed |
| WO-1998051659-A1 | SALICYLOXY α-CARBOXY ACIDS AND PREPARATION THEREOF | UNILEVER PLC (GB) | 1998-11-19 | — | — | WO | disclosed |
| WO-1998051274-A1 | COSMETIC SKIN CONDITIONING COMPOSITIONS | UNILEVER PLC (GB) | 1998-11-19 | — | — | WO | disclosed |
| US-5762947-A | CONTROLLING OILY SKIN | ELIZABETH ARDEN CO., DIVISION OF CONOPCO, INC. (US) | 1998-06-09 | — | — | US | disclosed |
| EP-0789029-A2 | Improved procedure for the preparation of pure(S,S)-N-(1-Ethoxycarbonyl-3-phenylprophyl)-alanin). | DSM Chemie Linz GmbH (AT) | 1997-08-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030187265-A1 | Process for synthesizing N-aryl piperazines with chiral N'-1-[benzoyl(2-pyridyl)amino]-2-propane substitution | TPH1, HTR1B, HTR1A | SMN1; SMN2 1936/4885HIF1A 2507/4885PPARG 1326/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.