Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | HTR3A | P46098 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.30 |
| ▸ | CFTR | P13569 | 1/20 | 0.30 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8094769 | 0.73 | PTGS2 (0.34) | ADRA2CPTGS2HRH1HTR3APDE4D | |
| Hydrochloric Acid SCHEMBL3675409 | 0.71 | — | — | |
| Hydrochloric Acid SCHEMBL4017281 | 0.65 | — | — | |
| Hydrochloric Acid SCHEMBL4022099 | 0.65 | — | — | |
| Hydrochloric Acid SCHEMBL9577145 | 0.65 | — | — | |
| Hydrochloric Acid SCHEMBL7208697 | 0.65 | ADRA2C (0.35) | ADRA2CPTGS2HRH1HTR3APDE4D | |
| Hydrochloric Acid SCHEMBL6553563 | 0.65 | CHRNB2 (0.33) | BCAT2 | |
| Hydrochloric Acid SCHEMBL8927340 | 0.65 | — | — | |
| Hydrochloric Acid SCHEMBL3388374 | 0.65 | — | — | |
| SCHEMBL31608569 | 0.63 | CYP17A1 (0.47) | PTGS2CFTRGOPC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8329841-B2 | Photoreactive polymer and method for preparing the same | LG CHEM, LTD. (KR) | 2012-12-11 | — | — | US | claimed |
| US-20120149848-A1 | PHOTOREACTIVE POLYMER AND METHOD FOR PREPARING THE SAME | LG CHEM, LTD. (KR) | 2012-06-14 | — | — | US | claimed |
| US-20100093955-A1 | PHOTOREACTIVE POLYMER AND METHOD FOR PREPARING THE SAME | LG CHEM, LTD. (KR) | 2010-04-15 | — | — | US | claimed |
| WO-2008115028-A1 | PHOTOREACTIVE POLYMER AND METHOD FOR PREPARING THE SAME | LG CHEM, LTD. (KR) | 2008-09-25 | — | — | WO | claimed |
| US-8329841-B2 | Photoreactive polymer and method for preparing the same | LG CHEM, LTD. (KR) | 2012-12-11 | — | — | US | disclosed |
| US-20120149848-A1 | PHOTOREACTIVE POLYMER AND METHOD FOR PREPARING THE SAME | LG CHEM, LTD. (KR) | 2012-06-14 | — | — | US | disclosed |
| US-20100093955-A1 | PHOTOREACTIVE POLYMER AND METHOD FOR PREPARING THE SAME | LG CHEM, LTD. (KR) | 2010-04-15 | — | — | US | disclosed |
| WO-2008115028-A1 | PHOTOREACTIVE POLYMER AND METHOD FOR PREPARING THE SAME | LG CHEM, LTD. (KR) | 2008-09-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120149848-A1 | PHOTOREACTIVE POLYMER AND METHOD FOR PREPARING THE SAME | PCNA, LCP1, CCND2 | ADRA2C 4150/4885PTGS2 3216/4885HRH1 4223/4885 |
| US-20100093955-A1 | PHOTOREACTIVE POLYMER AND METHOD FOR PREPARING THE SAME | PCNA, LCP1, CCND2 | ADRA2C 4150/4885PTGS2 3216/4885HRH1 4223/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.