Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | HTR3A | P46098 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 3/20 | 0.34 |
| ▸ | GPR3 | P46089 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6651543 | 0.80 | ADRA2C (0.36) | ADRA2CPTGS2HRH1HTR3APDE4D | |
| Hydrochloric Acid SCHEMBL7204700 | 0.72 | — | — | |
| Hydrochloric Acid SCHEMBL3388374 | 0.71 | — | — | |
| Hydrochloric Acid SCHEMBL3170692 | 0.64 | HTR2A (0.34) | HTR2AGPR3CYP1A2CYP2D6 | |
| Hydrochloric Acid SCHEMBL9519060 | 0.64 | ADRA2C (0.37) | ADRA2CPTGS2HRH1HTR3APDE4D | |
| Methane SCHEMBL8935403 | 0.63 | HTR2A (0.33) | HTR2A | |
| SCHEMBL29047783 | 0.62 | HTR2A (0.43) | ADRA2CPTGS2HRH1HTR3APDE4D | |
| SCHEMBL27885617 | 0.61 | HTR2A (0.52) | HTR2AGPR3CYP1A2CYP2D6 | |
| SCHEMBL29047784 | 0.60 | BCHE (0.42) | ADRA2CPTGS2HRH1HTR3APDE4D | |
| SCHEMBL29116619 | 0.60 | HTR2A (0.50) | ADRA2CPTGS2HRH1HTR3APDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0891382-B1 | ALPHA-OLEFIN-CYCLOOLEFIN COPOLYMERS AND PROCESS FOR THEIR PRODUCTION | TEIJIN LTD (JP) | 2003-05-28 | — | — | EP | disclosed |
| US-6388032-B1 | SEPARATION BY FILTRATION | TEIJIN LIMITED (JP) | 2002-05-14 | — | — | US | disclosed |
| EP-0891382-A1 | ALPHA-OLEFIN-CYCLOOLEFIN COPOLYMERS AND PROCESS FOR THEIR PRODUCTION | TEIJIN LIMITED (JP) | 1999-01-20 | — | — | EP | disclosed |
| WO-1998033830-A1 | ALPHA-OLEFIN-CYCLOOLEFIN COPOLYMERS AND PROCESS FOR THEIR PRODUCTION | TEIJIN LIMITED (JP) | 1998-08-06 | — | — | WO | disclosed |