Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA5A | P35218 | 4/20 | 0.81 |
| ▸ | CA5B | Q9Y2D0 | 4/20 | 0.81 |
| ▸ | CA3 | P07451 | 3/20 | 0.81 |
| ▸ | CA12 | O43570 | 3/20 | 0.81 |
| ▸ | CA2 | P00918 | 3/20 | 0.81 |
| ▸ | CA4 | P22748 | 3/20 | 0.81 |
| ▸ | CA6 | P23280 | 3/20 | 0.81 |
| ▸ | CA7 | P43166 | 3/20 | 0.81 |
| ▸ | CA9 | Q16790 | 3/20 | 0.81 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.81 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.67 |
| ▸ | POLB | P06746 | 1/20 | 0.67 |
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.59 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.55 |
| ▸ | F13A1 | P00488 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11981741 | 0.96 | CA5A (0.81) | CA5ACA5BCA3CA12CA2 | |
| SCHEMBL1274081 | 0.90 | CA3 (1.00) | CA5ACA5BCA3CA12CA2 | |
| SCHEMBL12936102 | 0.90 | CA3 (1.00) | CA5ACA5BCA3CA12CA2 | |
| SCHEMBL10228415 | 0.90 | CA3 (1.00) | CA5ACA5BCA3CA12CA2 | |
| SCHEMBL3149189 | 0.90 | ALDH1A1 (0.74) | CA5ACA5BCA3CA12CA2 | |
| SCHEMBL6490885 | 0.88 | ALDH1A1 (0.78) | CA5ACA5BCA3CA12CA2 | |
| Hydrochloric Acid SCHEMBL29241548 | 0.88 | SMN1; SMN2 (0.71) | CA5ACA5BCA3CA12CA2 | |
| SCHEMBL3142216 | 0.88 | CA3 (0.95) | CA5ACA5BCA3CA12CA2 | |
| SCHEMBL5367616 | 0.86 | MEN1 (0.79) | CA5ACA5BCA3CA12CA2 | |
| Hydrochloric Acid SCHEMBL29241679 | 0.86 | SMN1; SMN2 (0.75) | CA5ACA5BCA3CA12CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190048344-A1 | CHEMICAL MODIFICATIONS OF MONOMERS AND OLIGONUCLEOTIDES WITH CYCLOADDITION | ALNYLAM PHARMACEUTICALS INC (US) | 2019-02-14 | — | — | US | disclosed |
| US-20150209440-A1 | CONJUGATES, PARTICLES, COMPOSITIONS, AND RELATED METHODS OF USE | CERULEAN PHARMA INC. (US) | 2015-07-30 | — | — | US | disclosed |
| US-20150203847-A1 | CHEMICAL MODIFICATIONS OF MONOMERS AND OLIGONUCLEOTIDES WITH CYCLOADDITION | ALNYLAM PHARMACEUTICALS INC (US) | 2015-07-23 | — | — | US | disclosed |
| WO-2015057847-A1 | CONJUGATES, PARTICLES, COMPOSITIONS, AND RELATED METHODS | CERULEAN PHARMA INC. (US) | 2015-04-23 | — | — | WO | disclosed |
| US-20140296322-A1 | CONJUGATES, PARTICLES, COMPOSITIONS, AND RELATED METHODS OF USE | CERULEAN PHARMA INC. (US) | 2014-10-02 | — | — | US | disclosed |
| US-20140037573-A1 | CONJUGATES, PARTICLES, COMPOSITIONS, AND RELATED METHODS | CERULEAN PHARMA INC (US) | 2014-02-06 | — | — | US | disclosed |
| WO-2013126564-A1 | CONJUGATES, PARTICLES, COMPOSITIONS, AND RELATED METHODS | CERULEAN PHARMA INC. (US) | 2013-08-29 | — | — | WO | disclosed |
| US-20120302622-A1 | CONJUGATES, PARTICLES, COMPOSITIONS, AND RELATED METHODS | CERULEAN PHARMA INC. (US) | 2012-11-29 | — | — | US | disclosed |
| US-20120225129-A1 | CONJUGATES, PARTICLES, COMPOSITIONS, AND RELATED METHODS | CERULEAN PHARMA INC. (US) | 2012-09-06 | — | — | US | disclosed |
| WO-2012024526-A2 | CONJUGATES, PARTICLES, COMPOSITIONS, AND RELATED METHODS | CERULEAN PHARMA INC. (US) | 2012-02-23 | — | — | WO | disclosed |
| US-20100093973-A1 | POLY(AMINO ACID) COMPOUND HAVING INHIBITORY ACTIVITY ON ABSORPTION OF PHOSPHORUS AND PHOSPHORUS ABSORPTION INHIBITOR | AJINOMOTO CO., INC. (JP) | 2010-04-15 | — | — | US | disclosed |
| US-7001891-B1 | Biodegradable polycation composition for delivery of an anionic macromolecule | EFRAT BIOPOLYMERS LIMITED (IL) | 2006-02-21 | — | — | US | disclosed |
| EP-1200481-A1 | A BIODEGRADABLE POLYCATION COMPOSITION FOR DELIVERY OF AN ANIONIC MACROMOLECULE | Polygene Ltd. (IL) | 2002-05-02 | — | — | EP | disclosed |
| WO-2001007486-A1 | A BIODEGRADABLE POLYCATION COMPOSITION FOR DELIVERY OF AN ANIONIC MACROMOLECULE | POLYGENE LTD. (IL) | 2001-02-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150203847-A1 | CHEMICAL MODIFICATIONS OF MONOMERS AND OLIGONUCLEOTIDES WITH CYCLOADDITION | DNMT1, LCK, MCTS1 | CA5A 1286/4885CA5B 1510/4885CA3 4283/4885 |
| US-20190048344-A1 | CHEMICAL MODIFICATIONS OF MONOMERS AND OLIGONUCLEOTIDES WITH CYCLOADDITION | DNMT1, LCK, MCTS1 | CA5A 1286/4885CA5B 1510/4885CA3 4283/4885 |
| US-20140296322-A1 | CONJUGATES, PARTICLES, COMPOSITIONS, AND RELATED METHODS OF USE | CD44, DIS3, POLN | CA5A 1833/4885CA5B 1620/4885CA3 3138/4885 |
| US-20100093973-A1 | POLY(AMINO ACID) COMPOUND HAVING INHIBITORY ACTIVITY ON ABSORPTION OF PHOSPHORUS AND PHOSPHORUS ABSORPTION INHIBITOR | ALPI, SLC7A1, SLC34A1 | CA5A 2690/4885CA5B 2134/4885CA3 380/4885 |
| US-20140037573-A1 | CONJUGATES, PARTICLES, COMPOSITIONS, AND RELATED METHODS | SYNCRIP, EXOSC5, EXOSC9 | CA5A 2095/4885CA5B 1814/4885CA3 2912/4885 |
| US-20120302622-A1 | CONJUGATES, PARTICLES, COMPOSITIONS, AND RELATED METHODS | SYNCRIP, EXOSC5, EXOSC9 | CA5A 2095/4885CA5B 1814/4885CA3 2912/4885 |
| US-20150209440-A1 | CONJUGATES, PARTICLES, COMPOSITIONS, AND RELATED METHODS OF USE | CD44, DIS3, POLN | CA5A 1833/4885CA5B 1620/4885CA3 3138/4885 |
| US-20120225129-A1 | CONJUGATES, PARTICLES, COMPOSITIONS, AND RELATED METHODS | SYNCRIP, EXOSC5, EXOSC9 | CA5A 2095/4885CA5B 1814/4885CA3 2912/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.