Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | WDR5 | P61964 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MLYCD | O95822 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.41 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | MTOR | P42345 | 1/20 | 0.40 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3300941 | 0.88 | P2RX1 (0.48) | SMN1; SMN2HPGDMEN1KMT2AALDH1A1 | |
| SCHEMBL4056627 | 0.84 | MEN1 (0.49) | HPGDLMNAMEN1KMT2AMLYCD | |
| SCHEMBL3298777 | 0.84 | CCR2 (0.47) | HPGDLMNAHRH3MEN1KMT2A | |
| SCHEMBL3300343 | 0.83 | MLYCD (0.41) | LMNAMLYCDMTOR | |
| SCHEMBL3300225 | 0.82 | RORC (0.49) | SMN1; SMN2LMNAKMT2AMLYCDALDH1A1 | |
| SCHEMBL3304426 | 0.81 | TP53 (0.55) | SMN1; SMN2LMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL4357500 | 0.81 | HDAC3 (0.46) | MEN1KMT2AP2RX1TMPRSS4TRPV1 | |
| SCHEMBL4064957 | 0.80 | LMNA (0.53) | TSHRLMNAALDH1A1P2RX1TMPRSS4 | |
| SCHEMBL3297375 | 0.80 | TP53 (0.48) | MEN1KMT2AALDH1A1 | |
| SCHEMBL3302118 | 0.78 | RHOC (0.48) | SMN1; SMN2LMNAMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100093864-A1 | ANTI-INFECTIVE THIOUREA COMPOUNDS | LICA PHARMACEUTICALS (DK) | 2010-04-15 | — | — | US | claimed |
| US-20100093864-A1 | ANTI-INFECTIVE THIOUREA COMPOUNDS | LICA PHARMACEUTICALS (DK) | 2010-04-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100093864-A1 | ANTI-INFECTIVE THIOUREA COMPOUNDS | TST, TPX2, TPMT | TSHR 14/4885WDR5 3813/4885SMN1; SMN2 3982/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.