Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.70 |
| ▸ | L3MBTL1 | Q9Y468 | 7/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.70 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.70 |
| ▸ | NPC1 | O15118 | 5/20 | 0.70 |
| ▸ | RAB9A | P51151 | 4/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.70 |
| ▸ | XBP1 | P17861 | 1/20 | 0.70 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.70 |
| ▸ | GLO1 | Q04760 | 3/20 | 0.62 |
| ▸ | MEN1 | O00255 | 9/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.59 |
| ▸ | HTT | P42858 | 6/20 | 0.59 |
| ▸ | LMNA | P02545 | 5/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.59 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.59 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.57 |
| ▸ | HSP90AA1 | P07900 | 5/20 | 0.56 |
| ▸ | MPI | P34949 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6709708 | 0.82 | MAPT (0.70) | MAPTL3MBTL1KDM4ETDP1NPC1 | |
| SCHEMBL105461 | 0.82 | L3MBTL1 (1.00) | MAPTL3MBTL1KDM4ETDP1NPC1 | |
| SCHEMBL29624594 | 0.82 | L3MBTL1 (1.00) | MAPTL3MBTL1KDM4ETDP1NPC1 | |
| Hydrochloric Acid SCHEMBL6865586 | 0.81 | L3MBTL1 (0.97) | MAPTL3MBTL1KDM4ETDP1NPC1 | |
| SCHEMBL31157828 | 0.81 | L3MBTL1 (0.97) | MAPTL3MBTL1KDM4ETDP1NPC1 | |
| SCHEMBL5851373 | 0.79 | GLO1 (0.88) | MAPTL3MBTL1KDM4ETDP1NPC1 | |
| SCHEMBL5851384 | 0.79 | GLO1 (0.88) | MAPTL3MBTL1KDM4ETDP1NPC1 | |
| SCHEMBL1920452 | 0.78 | KDM4E (0.70) | MAPTL3MBTL1KDM4ETDP1NPC1 | |
| SCHEMBL8531824 | 0.78 | MEN1 (0.76) | MAPTL3MBTL1KDM4ETDP1NPC1 | |
| SCHEMBL15290177 | 0.78 | MAPT (0.64) | MAPTL3MBTL1KDM4ETDP1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5326697-A | NAD, hydroxybutyrate dehydrogenase, cystine reductase, cystine indicator dye | MILES INC. (US) | 1994-07-05 | — | — | US | claimed |
| US-5187265-A | Medical diagnosis | MILES INC. (US) | 1993-02-16 | — | — | US | claimed |
| US-5187105-A | Process for determining thiols using chromogenic benzoisothiazolone derivatives | MILES INC. (US) | 1993-02-16 | — | — | US | claimed |
| US-5128457-A | Medical diagnosis | MILES INC. (US) | 1992-07-07 | — | — | US | claimed |
| US-20180311237-A1 | COMPOSITIONS AND METHODS FOR PREVENTING AND TREATING MUCOSITIS AND WEIGHT LOSS | ZPNE GROUP GMBH (CH) | 2018-11-01 | — | — | US | disclosed |
| US-20150031701-A1 | COMPOSITIONS AND METHODS FOR PREVENTING AND TREATING MUCOSITIS AND WEIGHT LOSS | ZPNE GROUP GMBH (CH) | 2015-01-29 | — | — | US | disclosed |
| US-20130259930-A1 | Compositions and Methods for Preventing and Treating Mucositis and Weight Loss | CASCADE ESTATE LTD. (MU) | 2013-10-03 | — | — | US | disclosed |
| US-20120196825-A1 | COMPOSITIONS AND METHODS FOR MODULATING THE IMMUNE SYSTEM | SUPPORTIVE THERAPEUTICS AG (CH) | 2012-08-02 | — | — | US | disclosed |
| US-20100092547-A1 | COMPOSITIONS AND METHODS FOR PREVENTING AND TREATING MUCOSITIS AND WEIGHT LOSS | ZPNE GROUP GMBH (CH) | 2010-04-15 | — | — | US | disclosed |
| EP-2134347-A2 | COMPOSITIONS AND METHODS FOR PREVENTING AND TREATING MUCOSITIS AND WEIGHT LOSS | Prendergast, Patrick T. (AU) | 2009-12-23 | — | — | EP | disclosed |
| US-20090156546-A1 | Compositions and methods for modulating the immune system | SUPPORTIVE THERAPEUTICS AG (CH) | 2009-06-18 | — | — | US | disclosed |
| EP-2026810-A2 | COMPOSITIONS AND METHODS FOR MODULATING THE IMMUNE SYSTEM | Prendergast, Patrick T. (AU) | 2009-02-25 | — | — | EP | disclosed |
| US-5326697-A | NAD, hydroxybutyrate dehydrogenase, cystine reductase, cystine indicator dye | MILES INC. (US) | 1994-07-05 | — | — | US | disclosed |
| EP-0348826-B1 | Isobenzothiazolone chromogenic thiol indicators and their derivatives | MILES INC (US) | 1994-04-13 | — | — | EP | disclosed |
| US-5190863-A | Composition for determining the presence or concentration of D-β-hydroxybutyrate | MILES INC. (US) | 1993-03-02 | — | — | US | disclosed |
| US-5187265-A | Medical diagnosis | MILES INC. (US) | 1993-02-16 | — | — | US | disclosed |
| US-5187105-A | Process for determining thiols using chromogenic benzoisothiazolone derivatives | MILES INC. (US) | 1993-02-16 | — | — | US | disclosed |
| US-5130433-A | Indicators for detection of thiol | MILES INC. (US) | 1992-07-14 | — | — | US | disclosed |
| US-5128457-A | Medical diagnosis | MILES INC. (US) | 1992-07-07 | — | — | US | disclosed |
| EP-0463524-A1 | Composition and method of assaying for ketone bodies | Bayer Corporation (US) | 1992-01-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180311237-A1 | COMPOSITIONS AND METHODS FOR PREVENTING AND TREATING MUCOSITIS AND WEIGHT LOSS | SI, MTPN, MUC1 | MAPT 4455/4885L3MBTL1 1338/4885KDM4E 2898/4885 |
| US-20100092547-A1 | COMPOSITIONS AND METHODS FOR PREVENTING AND TREATING MUCOSITIS AND WEIGHT LOSS | MTAP, TPMT, MUC1 | MAPT 4845/4885L3MBTL1 1262/4885KDM4E 3627/4885 |
| US-20150031701-A1 | COMPOSITIONS AND METHODS FOR PREVENTING AND TREATING MUCOSITIS AND WEIGHT LOSS | SI, MTPN, MUC1 | MAPT 4455/4885L3MBTL1 1338/4885KDM4E 2898/4885 |
| US-20130259930-A1 | Compositions and Methods for Preventing and Treating Mucositis and Weight Loss | SI, MTPN, MUC1 | MAPT 4455/4885L3MBTL1 1338/4885KDM4E 2898/4885 |
| US-20090156546-A1 | Compositions and methods for modulating the immune system | MRE11, XPA, MPL | MAPT 4639/4885L3MBTL1 2069/4885KDM4E 3900/4885 |
| US-20120196825-A1 | COMPOSITIONS AND METHODS FOR MODULATING THE IMMUNE SYSTEM | MRE11, XPA, MPL | MAPT 4639/4885L3MBTL1 2069/4885KDM4E 3900/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.