Triphosphate

Triphosphate

SCHEMBL3305647

O.O=P(O)(O)OP(=O)(O)OP(=O)(O)O

nearest known ligand 0.64

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO

The experimentally established mechanism targets of Triphosphate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
FDPS known ✓ P14324 1/20 0.64
BLM P54132 1/20 0.64
TDP1 Q9NUW8 1/20 0.64
BTN3A1 O00481 4/20 0.42
MVD P53602 3/20 0.37
CA4 P22748 1/20 0.33
FNTA P49354 2/20 0.32
FNTB P49356 1/20 0.32
PGGT1B P53609 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Triphosphate SCHEMBL28446966 1.00 FDPS (0.64) FDPSBLMTDP1BTN3A1MVD
Triphosphate SCHEMBL9402756 1.00 FDPS (0.64) FDPSBLMTDP1BTN3A1MVD
Triphosphate SCHEMBL6223069 1.00 FDPS (0.64) FDPSBLMTDP1BTN3A1MVD
Triphosphate SCHEMBL11149492 1.00 FDPS (0.64) FDPSBLMTDP1BTN3A1MVD
Triphosphate SCHEMBL7797868 0.96 FDPS (0.60) FDPSBLMTDP1BTN3A1MVD
Triphosphate SCHEMBL9193700 0.96 FDPS (0.60) FDPSBLMTDP1BTN3A1MVD
Triphosphate SCHEMBL1302613 0.96 FDPS (0.60) FDPSBLMTDP1BTN3A1MVD
Water SCHEMBL22117081 0.96 FDPS (0.60) FDPSBLMTDP1BTN3A1MVD
Triphosphate SCHEMBL6724938 0.96 FDPS (0.60) FDPSBLMTDP1BTN3A1MVD
Triphosphate SCHEMBL5359470 0.96 FDPS (0.60) FDPSBLMTDP1BTN3A1MVD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230210729-A1 TOOTH WHITENING AND TOOTH SENSITIVITY STRIP OR FILM BSolve Limited (GB) 2023-07-06 US claimed
EP-4167922-A1 TOOTH WHITENING AND TOOTH SENSITIVITY STRIP OR FILM Bsolve Limited (GB) 2023-04-26 EP claimed
WO-2021255474-A1 TOOTH WHITENING AND TOOTH SENSITIVITY STRIP OR FILM BIOFILM LIMITED (GB) 2021-12-23 WO claimed
US-20230210729-A1 TOOTH WHITENING AND TOOTH SENSITIVITY STRIP OR FILM BSolve Limited (GB) 2023-07-06 US disclosed
EP-4167922-A1 TOOTH WHITENING AND TOOTH SENSITIVITY STRIP OR FILM Bsolve Limited (GB) 2023-04-26 EP disclosed
EP-4119169-A1 A CONSTRUCT FOR ARTICULAR CARTILAGE REGENERATION AND A METHOD OF PREPARATION Lietuvos Sveikatos Mokslu Universitetas (LT) 2023-01-18 EP disclosed
CN-114805527-A RAS inhibitory peptides and uses thereof 哈佛大学的校长及成员们 2022-07-29 CN disclosed
CN-106573032-B RAS inhibitory peptides and uses thereof 哈佛大学的校长及成员们 2022-03-18 CN disclosed
WO-2021255474-A1 TOOTH WHITENING AND TOOTH SENSITIVITY STRIP OR FILM BIOFILM LIMITED (GB) 2021-12-23 WO disclosed
CN-111036416-B Application of efficient inhibitor 5' -ATP-2Na in magnesite direct flotation decalcification 东北大学 2021-11-16 CN disclosed
CN-111620940-A RAS inhibitory peptides and uses thereof 哈佛大学的校长及成员们 2020-09-04 CN disclosed
US-9033908-B2 Device for the removal of toxic substances from blood Nederlandse Organisatie Voor Toegepast—Natuurwetenschappelijk Onderzoek Tno (NL) 2015-05-19 US disclosed
US-20100100027-A1 DEVICE FOR THE REMOVAL OF TOXIC SUBSTANCES FROM BLOOD NEDERLANDSE ORGANISATIE VOOR TOEGEPASTNATUURWETEN- SCHAPPELIJK ONDERZOEK TNO (NL) 2010-04-22 US disclosed
EP-2101842-A1 DEVICE FOR THE REMOVAL OF TOXIC SUBSTANCES FROM BLOOD Nederlandse Organisatie voor toegepast- natuurwetenschappelijk onderzoek TNO (NL) 2009-09-23 EP disclosed
EP-2072117-A1 Sorbent material Nederlandse Organisatie voor toegepast- natuurwetenschappelijk onderzoek TNO (NL) 2009-06-24 EP disclosed
WO-2008075951-A1 DEVICE FOR THE REMOVAL OF TOXIC SUBSTANCES FROM BLOOD NEDERLANDSE ORGANISATIE VOOR TOEGEPAST-NATUURWETENSCHAPPELIJK ONDERZOEK TNO (NL) 2008-06-26 WO disclosed
US-5552454-A LOW MOLECULAR WEIGHT LACTIC OR GLYCOLIC ACID POLYMER AND CALCIUM PHOSPHATE CERAMIC POWDER HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1996-09-03 US disclosed
US-4853225-A Process for implanting a medicament depot MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1989-08-01 US disclosed
US-4828749-A ALKALI METAL METASILICATES AND TRIPHOSPHATES, ACTIVE CHLORINE COMPOUND HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1989-05-09 US disclosed
US-4454054-A SPRAY DRYING SODIUM ORTHOPHOSPHATE AND A 2A OR ZINC COMPOUND HOECHST AKTIENGESELLSCHAFT (DE) 1984-06-12 US disclosed