SCHEMBL3305649

SCHEMBL3305649

O=P(O)(O)c1ncccn1

nearest known ligand 0.43

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.39
CA4 P22748 1/20 0.39
CA5A P35218 1/20 0.39
FDPS P14324 9/20 0.39
P2RX7 Q99572 1/20 0.39
CES2 O00748 1/20 0.35
CES1 P23141 1/20 0.35
HDAC8 Q9BY41 1/20 0.33
LMNA P02545 1/20 0.33
NAPRT Q6XQN6 1/20 0.33
P4HTM Q9NXG6 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
HSP90AA1 P07900 1/20 0.33
KDM4E B2RXH2 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1400873 0.71 CA2 (0.54) CA2CA4CA5AFDPSCES2
SCHEMBL29822627 0.71 CA2 (0.54) CA2CA4CA5AFDPSCES2
Phosphoric Acid SCHEMBL28095761 0.71 FDPS (0.41) FDPSP2RX7LMNA
Phosphoric Acid SCHEMBL28192934 0.71 HSP90AA1 (0.67) FDPSP2RX7HDAC8NAPRTHSP90AA1
SCHEMBL2595451 0.69 TDP1 (0.43) CA2CA4CA5AFDPSCES1
Phosphoric Acid SCHEMBL28528859 0.69 ALDH1A1 (0.50) FDPSKDM4E
SCHEMBL28361684 0.69 MMP1 (0.41) CA2CA4CA5AFDPS
Phosphoric Acid SCHEMBL459067 0.67 FDPS (0.38) FDPSP2RX7L3MBTL1
Phosphoric Acid SCHEMBL938025 0.67 FDPS (0.38) FDPSP2RX7L3MBTL1
Dipyridyl SCHEMBL10772309 0.67 KDM4E (0.70) FDPSHDAC8LMNAP4HTML3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100099869-A1 NOVEL NUCLEOTIDE ANALOGUES AS PRECUSOR MOLECULES FOR ANTIVIRALS CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE-CNRS (FR) 2010-04-22 US claimed
EP-2086990-A2 NOVEL NUCLEOTIDE ANALOGUES AS PERCURSOR MOLECULES FOR ANTIVIRALS Centre National De La Recherche Scientifique-CNRS (FR) 2009-08-12 EP claimed
WO-2008056264-A2 NOVEL NUCLEOTIDE ANALOGUES AS PERCURSOR MOLECULES FOR ANTIVIRALS CENTRE NATIONAL DE RECHERCHE SCIENTIFIQUE (CNRS) (FR) 2008-05-15 WO claimed
CN-101041669-A Non nucleoside reverse transcriptase inhibitors GILEAD SCIENCES INC (US) 2007-09-26 CN claimed
CN-1656109-A Non-nucleoside reverse transcriptase inhibitors GILEAD SCIENCES INC (US) 2005-08-17 CN claimed
US-5277788-A Twice-anodized aluminum article having an organo-phosphorus monolayer and process for making the article ALUMINUM COMPANY OF AMERICA (US) 1994-01-11 US claimed
EP-3416205-B1 LIGHT-EMITTING ELEMENT AND METHOD FOR MANUFACTURING SAME SUMITOMO CHEMICAL CO (JP) 2021-03-17 EP disclosed
US-10711091-B2 Light-emitting device and method for producing same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2020-07-14 US disclosed
US-20190048131-A1 LIGHT-EMITTING DEVICE AND METHOD FOR PRODUCING SAME CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2019-02-14 US disclosed
EP-3416205-A1 LIGHT-EMITTING ELEMENT AND METHOD FOR MANUFACTURING SAME Sumitomo Chemical Company, Ltd (JP) 2018-12-19 EP disclosed
US-8884011-B2 Nucleotide analogues as precursor molecules for antivirals CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE-CNRS (FR) 2014-11-11 US disclosed
US-8884011-B2 Nucleotide analogues as precursor molecules for antivirals CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE-CNRS (FR) 2014-11-11 US disclosed
CN-101759720-B Acyclic nucleoside phosphonate compounds or pharmaceutically acceptable salts thereof, preparation method, application, intermediate compounds thereof, and medicinal composition containing same SHANGHAI SINCH PHARMACEUTICALS TECHNOLOGY CO LTD 2013-01-23 CN disclosed
EP-2086990-A2 NOVEL NUCLEOTIDE ANALOGUES AS PERCURSOR MOLECULES FOR ANTIVIRALS Centre National De La Recherche Scientifique-CNRS (FR) 2009-08-12 EP disclosed
WO-2008056264-A3 NOVEL NUCLEOTIDE ANALOGUES AS PERCURSOR MOLECULES FOR ANTIVIRALS CT NAT DE RECH SCIENT CNRS (FR) 2008-10-30 WO disclosed
WO-2008056264-A2 NOVEL NUCLEOTIDE ANALOGUES AS PERCURSOR MOLECULES FOR ANTIVIRALS CENTRE NATIONAL DE RECHERCHE SCIENTIFIQUE (CNRS) (FR) 2008-05-15 WO disclosed
WO-2008056264-A2 NOVEL NUCLEOTIDE ANALOGUES AS PERCURSOR MOLECULES FOR ANTIVIRALS CENTRE NATIONAL DE RECHERCHE SCIENTIFIQUE (CNRS) (FR) 2008-05-15 WO disclosed
CN-101041669-A Non nucleoside reverse transcriptase inhibitors GILEAD SCIENCES INC (US) 2007-09-26 CN disclosed
CN-1656109-A Non-nucleoside reverse transcriptase inhibitors GILEAD SCIENCES INC (US) 2005-08-17 CN disclosed
US-5277788-A Twice-anodized aluminum article having an organo-phosphorus monolayer and process for making the article ALUMINUM COMPANY OF AMERICA (US) 1994-01-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10711091-B2 Light-emitting device and method for producing same SCO2, SUN2, SLC18A2 CA2 3004/4885CA4 2197/4885CA5A 2646/4885
US-20190048131-A1 LIGHT-EMITTING DEVICE AND METHOD FOR PRODUCING SAME SCO2, SUN2, SLC18A2 CA2 3004/4885CA4 2197/4885CA5A 2646/4885
US-20100099869-A1 NOVEL NUCLEOTIDE ANALOGUES AS PRECUSOR MOLECULES FOR ANTIVIRALS NUDT1, P2RY1, HPRT1 CA2 2546/4885CA4 2048/4885CA5A 2775/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.