Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.52 |
| ▸ | MEN1 | O00255 | 6/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | PGR | P06401 | 3/20 | 0.52 |
| ▸ | AR | P10275 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 7/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | CTSV | O60911 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3308208 | 0.82 | ALDH1A1 (0.55) | KMT2AMEN1GAALMNAMAPT | |
| SCHEMBL13668036 | 0.81 | CA1 (0.53) | KMT2AMEN1GAALMNAMAPT | |
| SCHEMBL13395857 | 0.81 | CA1 (0.55) | KMT2AMEN1LMNAMAPTALDH1A1 | |
| SCHEMBL13395859 | 0.79 | THRB (0.48) | KMT2AMEN1GAALMNAMAPT | |
| SCHEMBL3306459 | 0.79 | ALDH1A1 (0.49) | KMT2AGAALMNAMAPTALDH1A1 | |
| SCHEMBL28985111 | 0.78 | NPC1 (0.51) | KMT2AMEN1GAALMNAMAPT | |
| SCHEMBL20699783 | 0.78 | MEN1 (0.51) | KMT2AMEN1GAALMNAPGR | |
| SCHEMBL20699782 | 0.78 | MEN1 (0.51) | KMT2AMEN1GAALMNAPGR | |
| SCHEMBL15325818 | 0.78 | ALDH1A1 (0.60) | KMT2AMEN1GAALMNAMAPT | |
| SCHEMBL15003946 | 0.78 | ALDH1A1 (0.60) | KMT2AMEN1GAALMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100099886-A1 | N-HETEROCYCLIC CARBENE CATALYZED SYNTHESIS OF N-PHENYLISOXAZOLIDIN-5-ONE DERIVATIVE AND SYNTHESIS OF β-AMINO ACID ESTER DERIVATIVE | AGENCY FOR SCIENCE TECHNOLOGY AND RESEARCH | 2010-04-22 | — | — | US | disclosed |
| US-20100099886-A1 | N-HETEROCYCLIC CARBENE CATALYZED SYNTHESIS OF N-PHENYLISOXAZOLIDIN-5-ONE DERIVATIVE AND SYNTHESIS OF β-AMINO ACID ESTER DERIVATIVE | AGENCY FOR SCIENCE TECHNOLOGY AND RESEARCH | 2010-04-22 | — | — | US | disclosed |
| EP-2139873-A1 | N-HETEROCYCLIC CARBENE CATALYZED SYNTHESIS OF N-PHENYLISOXAZOLIDIN-5-ONE DERIVATIVE AND SYNTHESIS OF ß-AMINO ACID ESTER DERIVATIVE | Agency for Science, Technology and Research (SG) | 2010-01-06 | — | — | EP | disclosed |
| WO-2008115149-A9 | N-HETEROCYCLIC CARBENE CATALYZED SYNTHESIS OF N-PHENYLISOXAZOLIDIN-5-ONE DERIVATIVE AND SYNTHESIS OF β -AMINO ACID ESTER DERIVATIVE | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2009-10-15 | — | — | WO | disclosed |
| WO-2008115149-A9 | N-HETEROCYCLIC CARBENE CATALYZED SYNTHESIS OF N-PHENYLISOXAZOLIDIN-5-ONE DERIVATIVE AND SYNTHESIS OF β -AMINO ACID ESTER DERIVATIVE | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2009-10-15 | — | — | WO | disclosed |
| WO-2008115149-A1 | N-HETEROCYCLIC CARBENE CATALYZED SYNTHESIS OF N-PHENYLISOXAZOLIDIN-5-ONE DERIVATIVE AND SYNTHESIS OF β -AMINO ACID ESTER DERIVATIVE | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2008-09-25 | — | — | WO | disclosed |
| WO-2008115149-A1 | N-HETEROCYCLIC CARBENE CATALYZED SYNTHESIS OF N-PHENYLISOXAZOLIDIN-5-ONE DERIVATIVE AND SYNTHESIS OF β -AMINO ACID ESTER DERIVATIVE | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2008-09-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100099886-A1 | N-HETEROCYCLIC CARBENE CATALYZED SYNTHESIS OF N-PHENYLISOXAZOLIDIN-5-ONE DERIVATIVE AND SYNTHESIS OF β-AMINO ACID ESTER DERIVATIVE | DDC, NDC1, ADH1C | KMT2A 1659/4885MEN1 3691/4885GAA 2711/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.