Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | APEX1 | P27695 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.50 |
| ▸ | TUBB | P07437 | 2/20 | 0.50 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.50 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.50 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.50 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2780708 | 0.87 | ALDH1A1 (0.55) | GAACYP3A4TSHRALOX15CYP1A2 | |
| SCHEMBL30037244 | 0.87 | ALDH1A1 (0.55) | GAACYP3A4TSHRALOX15CYP1A2 | |
| SCHEMBL20526456 | 0.86 | ALDH1A1 (0.54) | GAACYP3A4TSHRALOX15CYP1A2 | |
| SCHEMBL1486251 | 0.85 | ALDH1A1 (0.60) | GAAALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL1936524 | 0.84 | CYP1A2 (0.58) | TRPV1GAACYP3A4TSHRALOX15 | |
| SCHEMBL3306706 | 0.82 | KDM1A (0.49) | ALDH1A1MEN1LMNAKMT2AKDM4E | |
| SCHEMBL8532510 | 0.81 | ALOX15 (0.62) | TRPV1GAACYP3A4TSHRALOX15 | |
| SCHEMBL19189935 | 0.81 | GAA (0.59) | GAACYP3A4ALDH1A1MEN1LMNA | |
| SCHEMBL18427657 | 0.81 | ALDH1A1 (0.44) | ALDH1A1MEN1LMNAKMT2AKDM4E | |
| SCHEMBL5541189 | 0.81 | GAA (0.50) | GAATSHRALDH1A1MEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100099676-A1 | SULFONYLUREA DERIVATIVE CAPABLE OF SELECTIVELY INHIBITING MMP-13 | SHIONOGI & CO., LTD. (JP) | 2010-04-22 | — | — | US | disclosed |
| EP-2128134-A1 | SULFONYLUREA DERIVATIVE CAPABLE OF SELECTIVELY INHIBITING MMP-13 | Shionogi&Co., Ltd. (JP) | 2009-12-02 | — | — | EP | disclosed |
| CN-1044906-C | 3(2H) -pyridazinone derivatives, process for their preparation and compositions containing them | NISSAN CHEMICAL IND LTD (JP) | 1999-09-01 | — | — | CN | disclosed |
| CN-1126470-A | Pyridazinone derivatives | NISSAN CHEMICAL IND LTD (JP) | 1996-07-10 | — | — | CN | disclosed |
| US-4388250-A | FROM HYDROXYBENZALDEHYDE | RHONE POULENC INC. (US) | 1983-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100099676-A1 | SULFONYLUREA DERIVATIVE CAPABLE OF SELECTIVELY INHIBITING MMP-13 | MMP13, MMP3, MMP26 | TRPV1 3702/4885GAA 1044/4885CYP3A4 1239/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.