Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.55 |
| ▸ | AR | P10275 | 1/20 | 0.55 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.55 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.55 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.55 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | FOS | P01100 | 1/20 | 0.53 |
| ▸ | TTR | P02766 | 1/20 | 0.53 |
| ▸ | JUN | P05412 | 1/20 | 0.53 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.53 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.53 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30037244 | 1.00 | ALDH1A1 (0.55) | ALDH1A1ALOX5TSHRCYP3A4TDP1 | |
| SCHEMBL20526456 | 0.98 | ALDH1A1 (0.54) | ALDH1A1ALOX5TSHRCYP3A4TDP1 | |
| SCHEMBL3307756 | 0.87 | TRPV1 (0.57) | ALDH1A1TSHRCYP3A4GAANFKB1 | |
| SCHEMBL1486251 | 0.85 | ALDH1A1 (0.60) | ALDH1A1TDP1GAALMNA | |
| SCHEMBL5833247 | 0.84 | TAAR1 (0.62) | ALDH1A1ALOX5TSHRCYP3A4TDP1 | |
| SCHEMBL20526453 | 0.84 | ALDH1A1 (0.56) | ALDH1A1TSHRTDP1GAALMNA | |
| SCHEMBL1548853 | 0.84 | ALOX5 (0.60) | ALDH1A1ALOX5TSHRCYP3A4TDP1 | |
| SCHEMBL5990841 | 0.82 | HTR7 (0.47) | ALDH1A1TSHRTDP1GAAMAPK1 | |
| SCHEMBL7768865 | 0.81 | FOS (0.62) | ALDH1A1TSHRCYP3A4TDP1GAA | |
| SCHEMBL11969383 | 0.81 | TAAR1 (0.62) | ALDH1A1ALOX5TSHRCYP3A4TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3383200-B1 | COMPOSITIONS | SYMRISE AG (DE) | 2019-11-06 | — | — | EP | claimed |
| EP-3383200-A1 | SUBSTANCE MIXTURES | Symrise AG (DE) | 2018-10-10 | — | — | EP | claimed |
| EP-2370177-B1 | NOVEL COSMETIC COMPOSITIONS HAVING HAIR GROWTH INHIBITING EFFECT | HENKEL AG & CO KGAA (DE) | 2017-11-15 | — | — | EP | claimed |
| US-8329948-B2 | Method for the synthesis of substituted formylamines and substituted amines | BOBYLEV MIKHAIL (US) | 2012-12-11 | — | — | US | claimed |
| CN-102001958-A | Method for synthesizing N-(3,4-dimethoxybenzyl)amide capsaicine homologous compounds | UNIV ZHEJIANG | 2011-04-06 | — | — | CN | claimed |
| EP-2175854-A1 | IMPROVED METHOD FOR THE SYNTHESIS OF SUBSTITUTED FORMYLAMINES AND SUBSTITUTED AMINES | University Of North Dakota Research Foundation (US) | 2010-04-21 | — | — | EP | claimed |
| US-20090143622-A1 | Method For The Synthesis Of Substituted Formylamines And Substituted Amines | BOBYLEV MIKHAIL | 2009-06-04 | — | — | US | claimed |
| WO-2009018353-A1 | IMPROVED METHOD FOR THE SYNTHESIS OF SUBSTITUTED FORMYLAMINES AND SUBSTITUTED AMINES | UNIVERSITY OF NORTH DAKOTA RESEARCH FOUNDATION (US) | 2009-02-05 | — | — | WO | claimed |
| CN-116685575-A | Novel cooling substances and formulations containing these cooling substances | 西姆莱斯股份公司 | 2023-09-01 | — | — | CN | disclosed |
| US-20230139835-A1 | ALLULOSE IN CRYSTALLINE FORM | SAVANNA INGREDIENTS GMBH (DE) | 2023-05-04 | — | — | US | disclosed |
| CN-115968259-A | Robust flavor emulsions | 国际香精香料公司 | 2023-04-14 | — | — | CN | disclosed |
| CN-110621654-B | TRPV1 modulator compounds | 安塔尔遗传学公司 | 2022-11-01 | — | — | CN | disclosed |
| US-11274073-B2 | TRPV1 modulator compounds | ANTALGENICS, S.L. (ES) | 2022-03-15 | — | — | US | disclosed |
| EP-3621950-B1 | TRPV1 MODULATOR COMPOUNDS | ANTALGENICS S L (ES) | 2021-12-15 | — | — | EP | disclosed |
| CN-102001958-A | Method for synthesizing N-(3,4-dimethoxybenzyl)amide capsaicine homologous compounds | UNIV ZHEJIANG | 2011-04-06 | — | — | CN | disclosed |
| CN-101827632-A | Process for preparing aromatic chewing foam for cosmetics | BAYER MATERIALSCIENCE AG | 2010-09-08 | — | — | CN | disclosed |
| EP-1215258-B1 | Flavor composition for food and drink or for oral care preparation | TAKASAGO PERFUMERY CO LTD (JP) | 2010-02-17 | — | — | EP | disclosed |
| CN-1878745-A | Use of alkene carboxylic acid N-alkylamides as odorants | SYMRISE GMBH & CO KG (DE) | 2006-12-13 | — | — | CN | disclosed |
| US-6673756-B2 | MULTILAYER; CUTTING, JOINING UNDER PRESSURE | SYMRISE GMBH & CO. KG (DE) | 2004-01-06 | — | — | US | disclosed |
| US-20020173436-A1 | Multilayer; cutting, joining under pressure | SYMRISE GMBH & CO. KG (DE) | 2002-11-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11274073-B2 | TRPV1 modulator compounds | TRPV1, TRPA1, TRPV3 | ALDH1A1 2059/4885ALOX5 550/4885TSHR 530/4885 |
| US-20230139835-A1 | ALLULOSE IN CRYSTALLINE FORM | SI, SORD, NOTUM | ALDH1A1 2204/4885ALOX5 2107/4885TSHR 4825/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.