Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26799180 | 0.86 | ALDH1A1 (0.48) | ALDH1A1PTPN5KDM4EPKMHPGD | |
| SCHEMBL1042998 | 0.84 | CES2 (0.40) | ALDH1A1TSHRCES2MAPTCA1 | |
| SCHEMBL1536699 | 0.80 | GAA (0.45) | ALDH1A1KDM4EHPGDHSD17B10TSHR | |
| SCHEMBL7748802 | 0.78 | PTPN5 (0.41) | ALDH1A1PTPN5KDM4EPKMHPGD | |
| SCHEMBL205002 | 0.77 | ALDH1A1 (0.50) | ALDH1A1PTPN5KDM4EPKMHPGD | |
| SCHEMBL5667400 | 0.77 | CES2 (0.36) | CES2MAPTNOTUMGABRB3CACNA1H | |
| SCHEMBL27764178 | 0.77 | PTPN5 (0.44) | ALDH1A1PTPN5KDM4EPKMHPGD | |
| SCHEMBL26799178 | 0.76 | CA12 (0.38) | ALDH1A1KDM4ETSHRGAAGLA | |
| SCHEMBL10242061 | 0.76 | NOTUM (0.38) | CES2NOTUMGABRPGABRDGABRA1 | |
| SCHEMBL27082431 | 0.76 | PTPN5 (0.42) | ALDH1A1PTPN5KDM4EPKMHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260052896-A1 | METAL CARBENE COMPLEX AND ITS USE | UNIV CITY HONG KONG (HK) | 2026-02-19 | — | — | US | disclosed |
| US-12252640-B2 | Phosphors based on carbene metal complex | CITY UNIVERSITY OF HONG KONG (HK) | 2025-03-18 | — | — | US | disclosed |
| CN-117945984-A | Organic compound containing polyfluoro-substituted glutarimide or succinimide and organic electroluminescent device containing same | 江苏三月科技股份有限公司 | 2024-04-30 | — | — | CN | disclosed |
| US-11713293-B2 | Substituted biaryl sulfonamides and the use thereof | NOVOMEDIX, LLC (US) | 2023-08-01 | — | — | US | disclosed |
| US-20220002240-A1 | SUBSTITUTED BIARYL SULFONAMIDES AND THE USE THEREOF | NOVOMEDIX LLC (US) | 2022-01-06 | — | — | US | disclosed |
| US-20200062700-A1 | SUBSTITUTED BIARYL SULFONAMIDES AND THE USE THEREOF | NOVOMEDIX LLC (US) | 2020-02-27 | — | — | US | disclosed |
| US-20180327353-A1 | SUBSTITUTED BIARYL SULFONAMIDES AND THE USE THEREOF | NOVOMEDIX LLC (US) | 2018-11-15 | — | — | US | disclosed |
| US-10040757-B2 | Substituted biaryl sulfonamides and the use thereof | NOVOMEDIX, LLC (US) | 2018-08-07 | — | — | US | disclosed |
| EP-2925718-B1 | SUBSTITUTED BIARYL SULFONAMIDES AND THE USE THEREOF | NOVOMEDIX LLC (US) | 2018-08-01 | — | — | EP | disclosed |
| US-20170158627-A1 | SUBSTITUTED BIARYL SULFONAMIDES AND THE USE THEREOF | NOVOMEDIX, LLC | 2017-06-08 | — | — | US | disclosed |
| EP-1512396-A1 | INHIBITORS AGAINST THE ACTIVATION OF AP-1 AND NFAT | Institute of Medicinal Molecular Design, Inc. (JP) | 2005-03-09 | — | — | EP | disclosed |
| EP-1510207-A1 | THERAPEUTIC DRUG FOR DIABETES | Institute of Medicinal Molecular Design, Inc. (JP) | 2005-03-02 | — | — | EP | disclosed |
| EP-1510210-A1 | IMMUNITY-RELATED PROTEIN KINASE INHIBITORS | Institute of Medicinal Molecular Design, Inc. (JP) | 2005-03-02 | — | — | EP | disclosed |
| US-20040259877-A1 | Inhibitors against the production and release of inflammatory cytokines | INSTITUTE OF MEDICINAL MOLECULAR DESIGN, INC. (JP) | 2004-12-23 | — | — | US | disclosed |
| US-20040138301-A1 | Chemical uncouplers for the treatment of obesity | HIGH POINT PHARMACEUTICALS, LLC | 2004-07-15 | — | — | US | disclosed |
| WO-2004041256-A2 | SAFE CHEMICAL UNCOUPLERS FOR THE TREATMENT OF OBESITY | NOVO NORDISK A/S (DK) | 2004-05-21 | — | — | WO | disclosed |
| EP-1352650-A1 | INHIBITORS AGAINST THE PRODUCTION AND RELEASE OF INFLAMMATORY CYTOKINES | Institute of Medicinal Molecular Design, Inc. (JP) | 2003-10-15 | — | — | EP | disclosed |
| WO-2003051123-A1 | ISOTHIAZOLYLAMINOCARBONYL DERIVATIVES AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2003-06-26 | — | — | WO | disclosed |
| US-6433023-B1 | ADMINISTERING 4-CHLORO-3,5-DINITROBENZOTRIFLUORIDE OR DERIVATIVE AS ANTIPROTOZOA AGENT | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY | 2002-08-13 | — | — | US | disclosed |
| WO-1995033711-A1 | PHENYL BENZOYL(NICOTINOYL) UREA DERIVATIVES | HANWHA CORPORATION (KR) | 1995-12-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180327353-A1 | SUBSTITUTED BIARYL SULFONAMIDES AND THE USE THEREOF | EIF2AK2, TP53, KRAS | ALDH1A1 2107/4885PTPN5 3286/4885KDM4E 568/4885 |
| US-11713293-B2 | Substituted biaryl sulfonamides and the use thereof | EIF2AK2, TP53, KRAS | ALDH1A1 2107/4885PTPN5 3286/4885KDM4E 568/4885 |
| US-20220002240-A1 | SUBSTITUTED BIARYL SULFONAMIDES AND THE USE THEREOF | EIF2AK2, TP53, KRAS | ALDH1A1 2041/4885PTPN5 3191/4885KDM4E 603/4885 |
| US-20170158627-A1 | SUBSTITUTED BIARYL SULFONAMIDES AND THE USE THEREOF | EIF2AK2, TP53, KRAS | ALDH1A1 2107/4885PTPN5 3286/4885KDM4E 568/4885 |
| US-20200062700-A1 | SUBSTITUTED BIARYL SULFONAMIDES AND THE USE THEREOF | EIF2AK2, TP53, KRAS | ALDH1A1 2107/4885PTPN5 3286/4885KDM4E 568/4885 |
| US-10040757-B2 | Substituted biaryl sulfonamides and the use thereof | EIF2AK2, TP53, KRAS | ALDH1A1 2107/4885PTPN5 3286/4885KDM4E 568/4885 |
| US-12252640-B2 | Phosphors based on carbene metal complex | OCIAD1, PDCD5, OCIAD2 | ALDH1A1 3326/4885PTPN5 3954/4885KDM4E 4249/4885 |
| US-20260052896-A1 | METAL CARBENE COMPLEX AND ITS USE | CYBA, OPRD1, OXER1 | ALDH1A1 1215/4885PTPN5 3747/4885KDM4E 4075/4885 |
| US-20040138301-A1 | Chemical uncouplers for the treatment of obesity | PC, CPT2, IDH2 | ALDH1A1 2021/4885PTPN5 1771/4885KDM4E 2909/4885 |
| US-20040259877-A1 | Inhibitors against the production and release of inflammatory cytokines | NFKBIA, IL1B, IKBKB | ALDH1A1 1025/4885PTPN5 912/4885KDM4E 3631/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.