Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN5 | P54829 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.38 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.38 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3131496 | 0.86 | PTPN5 (0.47) | PTPN5ALDH1A1TSHRHPGDCYP3A4 | |
| SCHEMBL1042850 | 0.84 | ALDH1A1 (0.45) | ALDH1A1TSHRHPGDCYP3A4ALOX15 | |
| SCHEMBL1040870 | 0.80 | TSHR (0.45) | ALDH1A1TSHRCYP3A4ALOX15KDM4E | |
| SCHEMBL10776564 | 0.80 | CYP3A4 (0.41) | ALDH1A1TSHRHPGDCYP3A4ALOX15 | |
| SCHEMBL1769094 | 0.80 | PTPN5 (0.42) | PTPN5ALDH1A1TSHRHPGDCYP3A4 | |
| SCHEMBL31304780 | 0.80 | PTPN5 (0.42) | PTPN5ALDH1A1TSHRHPGDCYP3A4 | |
| SCHEMBL9610071 | 0.78 | RAPGEF4 (0.42) | PTPN5ALDH1A1TSHRHPGDCYP3A4 | |
| SCHEMBL9560970 | 0.78 | EPAS1 (0.37) | TSHRGAAPOLBGLACA12 | |
| SCHEMBL330815 | 0.78 | ALDH1A1 (0.43) | PTPN5ALDH1A1TSHRHPGDKDM4E | |
| SCHEMBL11055186 | 0.78 | PTPN5 (0.41) | PTPN5ALDH1A1TSHRHPGDCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0912502-B1 | 2-CHLORO-3,5-BIS(TRIFLUOROMETHYL)PHENYL BENZOYL UREA DERIVATIVE AND PROCESS FOR PREPARING THE SAME | DONGBU HANNONG CHEMICAL CO LTD (KR) | 2001-01-17 | — | — | EP | claimed |
| US-6022882-A | POTENT GROWTH-RETARDING ACTIVITY AGAINST PESTS | DONGBU HANNONG CHEMICAL CO., LTD. (KR) | 2000-02-08 | — | — | US | claimed |
| EP-0912502-A1 | 2-CHLORO-3,5-BIS(TRIFLUOROMETHYL)PHENYL BENZOYL UREA DERIVATIVE AND PROCESS FOR PREPARING THE SAME | Hanwha Corporation (KR) | 1999-05-06 | — | — | EP | claimed |
| WO-1998000394-A1 | 2-CHLORO-3,5-BIS(TRIFLUOROMETHYL)PHENYL BENZOYL UREA DERIVATIVE AND PROCESS FOR PREPARING THE SAME | HANWHA CORPORATION (KR) | 1998-01-08 | — | — | WO | claimed |
| US-12054484-B2 | Substituted tetrahydropyrans as CCR2 modulators | CHEMOCENTRYX, INC. (US) | 2024-08-06 | — | — | US | disclosed |
| US-11713293-B2 | Substituted biaryl sulfonamides and the use thereof | NOVOMEDIX, LLC (US) | 2023-08-01 | — | — | US | disclosed |
| US-20230180754-A1 | HETEROCYCLIC COMPOUNDS FOR THE CONTROL OF INVERTEBRATE PESTS | BASF SE (DE) | 2023-06-15 | — | — | US | disclosed |
| CN-109574956-B | Thiadiazole amide compound and application thereof | 沈阳中化农药化工研发有限公司 | 2023-04-07 | — | — | CN | disclosed |
| EP-4149936-A1 | HETEROCYCLIC COMPOUNDS FOR THE CONTROL OF INVERTEBRATE PESTS | BASF SE (DE) | 2023-03-22 | — | — | EP | disclosed |
| CN-115551848-A | Heterocyclic compounds for controlling invertebrate pests | 巴斯夫欧洲公司 | 2022-12-30 | — | — | CN | disclosed |
| US-20220153733-A1 | SUBSTITUTED TETRAHYDROPYRANS AS CCR2 MODULATORS | CHEMOCENTRYX, INC. | 2022-05-19 | — | — | US | disclosed |
| US-20220153733-A1 | SUBSTITUTED TETRAHYDROPYRANS AS CCR2 MODULATORS | CHEMOCENTRYX, INC. | 2022-05-19 | — | — | US | disclosed |
| EP-2925718-A1 | SUBSTITUTED BIARYL SULFONAMIDES AND THE USE THEREOF | Novomedix, LLC (US) | 2015-10-07 | — | — | EP | disclosed |
| US-20140221411-A1 | 2-HYDROXYARYLAMIDE DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, PREPARATION METHOD THEREOF, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING CANCER CONTAINING SAME AS ACTIVE INGREDIENT | KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) | 2014-08-07 | — | — | US | disclosed |
| US-20140155477-A1 | SUBSTITUTED BIARYL SULFONAMIDES AND THE USE THEREOF | NOVOMEDIX, LLC (US) | 2014-06-05 | — | — | US | disclosed |
| WO-2014085633-A1 | SUBSTITUTED BIARYL SULFONAMIDES AND THE USE THEREOF | NOVOMEDIX, LLC (US) | 2014-06-05 | — | — | WO | disclosed |
| EP-0912502-B1 | 2-CHLORO-3,5-BIS(TRIFLUOROMETHYL)PHENYL BENZOYL UREA DERIVATIVE AND PROCESS FOR PREPARING THE SAME | DONGBU HANNONG CHEMICAL CO LTD (KR) | 2001-01-17 | — | — | EP | disclosed |
| US-6022882-A | POTENT GROWTH-RETARDING ACTIVITY AGAINST PESTS | DONGBU HANNONG CHEMICAL CO., LTD. (KR) | 2000-02-08 | — | — | US | disclosed |
| EP-0912502-A1 | 2-CHLORO-3,5-BIS(TRIFLUOROMETHYL)PHENYL BENZOYL UREA DERIVATIVE AND PROCESS FOR PREPARING THE SAME | Hanwha Corporation (KR) | 1999-05-06 | — | — | EP | disclosed |
| WO-1998000394-A1 | 2-CHLORO-3,5-BIS(TRIFLUOROMETHYL)PHENYL BENZOYL UREA DERIVATIVE AND PROCESS FOR PREPARING THE SAME | HANWHA CORPORATION (KR) | 1998-01-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11713293-B2 | Substituted biaryl sulfonamides and the use thereof | EIF2AK2, TP53, KRAS | PTPN5 3286/4885ALDH1A1 2107/4885TSHR 3529/4885 |
| US-20230180754-A1 | HETEROCYCLIC COMPOUNDS FOR THE CONTROL OF INVERTEBRATE PESTS | DDT, ACHE, CYCS | PTPN5 1914/4885ALDH1A1 1384/4885TSHR 3767/4885 |
| US-12054484-B2 | Substituted tetrahydropyrans as CCR2 modulators | CCR2, CCR1, CCR5 | PTPN5 868/4885ALDH1A1 538/4885TSHR 1129/4885 |
| US-20140155477-A1 | SUBSTITUTED BIARYL SULFONAMIDES AND THE USE THEREOF | EIF2AK2, TP53, KRAS | PTPN5 3286/4885ALDH1A1 2107/4885TSHR 3529/4885 |
| US-20140221411-A1 | 2-HYDROXYARYLAMIDE DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, PREPARATION METHOD THEREOF, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING CANCER CONTAINING SAME AS ACTIVE INGREDIENT | TMPRSS2, TMPRSS4, PRSS2 | PTPN5 995/4885ALDH1A1 740/4885TSHR 3299/4885 |
| US-20220153733-A1 | SUBSTITUTED TETRAHYDROPYRANS AS CCR2 MODULATORS | CCR2, CCR1, CCR5 | PTPN5 823/4885ALDH1A1 520/4885TSHR 1064/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.