Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | DHFR | P00374 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.38 |
| ▸ | FEN1 | P39748 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | JAK1 | P23458 | 1/20 | 0.37 |
| ▸ | TYK2 | P29597 | 1/20 | 0.37 |
| ▸ | JAK3 | P52333 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29962162 | 0.82 | AHR (0.54) | ALDH1A1HSD17B10L3MBTL1DHFRTSHR | |
| SCHEMBL331060 | 0.82 | AHR (0.54) | ALDH1A1HSD17B10L3MBTL1DHFRTSHR | |
| SCHEMBL1300021 | 0.82 | ALDH1A1 (0.61) | ALDH1A1HSD17B10L3MBTL1DHFRTSHR | |
| SCHEMBL23502859 | 0.81 | ALDH1A1 (0.52) | ALDH1A1HSD17B10L3MBTL1DHFRTSHR | |
| SCHEMBL18238557 | 0.78 | ESR2 (0.58) | ALDH1A1HSD17B10L3MBTL1DHFRTSHR | |
| SCHEMBL397260 | 0.78 | PTGS2 (0.58) | ALDH1A1HSD17B10L3MBTL1DHFRTSHR | |
| SCHEMBL8098489 | 0.78 | CYP3A4 (0.48) | ALDH1A1HSD17B10L3MBTL1DHFRTSHR | |
| SCHEMBL31161110 | 0.78 | PTGS2 (0.58) | ALDH1A1HSD17B10L3MBTL1DHFRTSHR | |
| SCHEMBL1558220 | 0.76 | ALDH1A1 (0.54) | ALDH1A1HSD17B10L3MBTL1DHFRTSHR | |
| SCHEMBL27354585 | 0.75 | CYP1A2 (0.49) | ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2640707-B1 | 5-HALOGENOPYRAZOLECARBOXAMIDES | BAYER IP GMBH (DE) | 2017-03-15 | — | — | EP | disclosed |
| US-9375004-B2 | 5-halogenopyrazolecarboxamides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-06-28 | — | — | US | disclosed |
| US-20130296269-A1 | 5-Halogenopyrazolecarboxamides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-11-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130296269-A1 | 5-Halogenopyrazolecarboxamides | CYP3A5, CBR3, HDHD5 | ALDH1A1 3455/4885HSD17B10 2688/4885L3MBTL1 2393/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.