SCHEMBL3316490

SCHEMBL3316490

[CH2]CCCC(CCC)c1ccccc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AOC3 Q16853 2/20 0.40
SIGMAR1 Q99720 1/20 0.38
ESR1 P03372 1/20 0.37
ESR2 Q92731 1/20 0.37
LMNA P02545 1/20 0.36
HRH1 P35367 6/20 0.36
HTR2A P28223 5/20 0.36
POLB P06746 1/20 0.35
HDAC3 O15379 1/20 0.35
HDAC4 P56524 1/20 0.35
HDAC1 Q13547 1/20 0.35
HDAC7 Q8WUI4 1/20 0.35
HDAC2 Q92769 1/20 0.35
HDAC10 Q969S8 1/20 0.35
HDAC11 Q96DB2 1/20 0.35
HDAC8 Q9BY41 1/20 0.35
HDAC6 Q9UBN7 1/20 0.35
HDAC9 Q9UKV0 1/20 0.35
HDAC5 Q9UQL6 1/20 0.35
KDM4E B2RXH2 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17183765 0.94 SIGMAR1 (0.41) AOC3SIGMAR1ESR1ESR2LMNA
SCHEMBL17183643 0.93 SIGMAR1 (0.40) AOC3SIGMAR1ESR1ESR2LMNA
SCHEMBL15563156 0.92 POLB (0.41) AOC3SIGMAR1LMNAHRH1HTR2A
SCHEMBL1921279 0.91 SIGMAR1 (0.41) SIGMAR1HTR2APOLBKDM4EALDH1A1
SCHEMBL29165486 0.89 NR1I2 (0.43) SIGMAR1HTR2A
SCHEMBL15563133 0.89 NR1I2 (0.43) SIGMAR1HTR2A
SCHEMBL3375650 0.88 AOC3 (0.42) AOC3SIGMAR1ESR1ESR2LMNA
SCHEMBL3680840 0.87 POLB (0.41) AOC3SIGMAR1LMNAHRH1HTR2A
SCHEMBL3385362 0.86 LMNA (0.42) AOC3SIGMAR1LMNAHRH1HTR2A
SCHEMBL2052039 0.86 POLB (0.45) AOC3SIGMAR1ESR1ESR2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2132183-B1 LISOFYLLINE ANALOGS AND METHODS FOR USE Univ Virginia Patent Found (US) 2015-06-03 EP claimed
US-20100105690-A1 LISOFYLLINE ANALOGS AND METHODS FOR USE UNIVERSITY OF VIRGINIA PATENT FOUNDATION 2010-04-29 US claimed
EP-2132183-A1 LISOFYLLINE ANALOGS AND METHODS FOR USE University Of Virginia Patent Foundation (US) 2009-12-16 EP claimed
WO-2008108842-A1 LISOFYLLINE ANALOGS AND METHODS FOR USE UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) 2008-09-12 WO claimed
US-20210205199-A1 Dermatological Cosmetic Composition Comprising an SDKP Peptide or an Analog Thereof RPM DERMATOLOGIE (FR) 2021-07-08 US disclosed
EP-3416730-B1 DERMATOLOGICAL COSMETIC COMPOSITION COMPRISING AN SDKP PEPTIDE OR AN ANALOG THEREOF RPM DERMATOLOGIE (FR) 2021-07-07 EP disclosed
WO-2021107870-A1 ANTIMICROBIAL AGENT, COATING FORMULATION, COMPOSITE SURFACE COATING AND METHODS OF PREPARING THE SAME AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2021-06-03 WO disclosed
EP-3239111-B1 CURABLE COMPOSITION, TRANSFER FILM, FRONT PLATE OF IMAGE DISPLAY DEVICE, FRONT PLATE-INTEGRATED SENSOR, IMAGE DISPLAY DEVICE, AND MANUFACTURING METHOD FOR FRONT PLATE OF IMAGE DISPLAY DEVICE FUJIFILM CORP (JP) 2021-02-17 EP disclosed
EP-3416730-A1 DERMATOLOGICAL COSMETIC COMPOSITION COMPRISING AN SDKP PEPTIDE OR AN ANALOG THEREOF RPM Dermatologie (FR) 2018-12-26 EP disclosed
US-10035927-B2 Coloring composition for decoration, decorative material, base material having decorative material, transfer material, touch panel, and information display device FUJIFILM CORPORATION (JP) 2018-07-31 US disclosed
EP-3239111-A1 CURABLE COMPOSITION, TRANSFER FILM, FRONT PLATE OF IMAGE DISPLAY DEVICE, FRONT PLATE-INTEGRATED SENSOR, IMAGE DISPLAY DEVICE, AND MANUFACTURING METHOD FOR FRONT PLATE OF IMAGE DISPLAY DEVICE FUJIFILM Corporation (JP) 2017-11-01 EP disclosed
US-9802902-B2 Antifungal compound AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2017-10-31 US disclosed
CN-104321195-A Transfer film, method for producing capacitive input device, capacitive input device, and image display device provided with same FUJIFILM CORP 2015-01-28 CN disclosed
US-8871764-B2 Lisofylline analogs and methods for use UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) 2014-10-28 US disclosed
WO-2014025314-A1 An Antifungal Compound AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2014-02-13 WO disclosed
US-20130137693-A1 LISOFYLLINE ANALOGS AND METHODS FOR USE UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) 2013-05-30 US disclosed
US-20100105690-A1 LISOFYLLINE ANALOGS AND METHODS FOR USE UNIVERSITY OF VIRGINIA PATENT FOUNDATION 2010-04-29 US disclosed
EP-0707585-A1 BICYCLIC TETRAHYDRO PYRAZOLOPYRIDINES PFIZER INC. (US) 1996-04-24 EP disclosed
US-5508300-A INHIBIT PHOSPHODIESTERASE AND PRODUCTION OF TUMOR NECROSIS FACTOR; TREATING INFLAMMATORY DISEASES PFIZER INC. (US) 1996-04-16 US disclosed
WO-1995001980-A1 BICYCLIC TETRAHYDRO PYRAZOLOPYRIDINES PFIZER INC. (US) 1995-01-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100105690-A1 LISOFYLLINE ANALOGS AND METHODS FOR USE IAPP, RNASE1, CTSA AOC3 4091/4885SIGMAR1 2354/4885ESR1 4873/4885
US-20130137693-A1 LISOFYLLINE ANALOGS AND METHODS FOR USE IAPP, RNASE1, CTSA AOC3 4091/4885SIGMAR1 2354/4885ESR1 4873/4885
US-20210205199-A1 Dermatological Cosmetic Composition Comprising an SDKP Peptide or an Analog Thereof CUTA, SDAD1, SDCBP AOC3 3261/4885SIGMAR1 3237/4885ESR1 4638/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.