Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.61 |
| ▸ | MAPT | P10636 | 6/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.55 |
| ▸ | USP2 | O75604 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | TLR2 | O60603 | 3/20 | 0.51 |
| ▸ | CNR2 | P34972 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19140470 | 0.97 | ALDH1A1 (0.66) | ALDH1A1KDM4EMAPTHPGDSMN1; SMN2 | |
| SCHEMBL18499679 | 0.83 | ALDH1A1 (0.60) | ALDH1A1KDM4EMAPTHPGDSMN1; SMN2 | |
| SCHEMBL19320697 | 0.81 | KDM4E (0.51) | ALDH1A1KDM4EMAPTHPGDSMN1; SMN2 | |
| SCHEMBL2181401 | 0.80 | ALDH1A1 (0.67) | ALDH1A1KDM4EMAPTHPGDSMN1; SMN2 | |
| SCHEMBL22774533 | 0.80 | ALDH1A1 (0.57) | ALDH1A1KDM4EMAPTHPGDSMN1; SMN2 | |
| SCHEMBL6999008 | 0.80 | ALDH1A1 (0.69) | ALDH1A1KDM4EMAPTHPGDSMN1; SMN2 | |
| SCHEMBL31435555 | 0.80 | ALDH1A1 (0.44) | ALDH1A1KDM4EMAPTHPGDSMN1; SMN2 | |
| SCHEMBL19308757 | 0.79 | ALDH1A1 (0.65) | ALDH1A1KDM4EMAPTHPGDSMN1; SMN2 | |
| SCHEMBL18430418 | 0.78 | ALDH1A1 (0.66) | ALDH1A1KDM4EMAPTHPGDSMN1; SMN2 | |
| SCHEMBL22774938 | 0.78 | ALDH1A1 (0.55) | ALDH1A1KDM4EMAPTHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12624023-B2 | Sulfonylurea derivatives and uses thereof | NodThera Limited (GB) | 2026-05-12 | — | — | US | disclosed |
| EP-3983407-B1 | SULFONYLUREA DERIVATIVES AND USES THEREOF | NODTHERA LTD (GB) | 2025-11-12 | — | — | EP | disclosed |
| CN-114222739-B | Sulfonylurea derivatives and their use | 诺瑟拉有限公司 | 2025-02-11 | — | — | CN | disclosed |
| US-20230083495-A1 | SULFONYLUREA DERIVATIVES AND USES THEREOF | NodThera Limited (GB) | 2023-03-16 | — | — | US | disclosed |
| EP-3983407-A1 | SULFONYLUREA DERIVATIVES AND USES THEREOF | Nodthera Limited (GB) | 2022-04-20 | — | — | EP | disclosed |
| CN-114222739-A | Sulfonylurea derivatives and use thereof | 诺瑟拉有限公司 | 2022-03-22 | — | — | CN | disclosed |
| WO-2020249664-A1 | SULFONYLUREA DERIVATIVES AND USES THEREOF | NodThera Limited (GB) | 2020-12-17 | — | — | WO | disclosed |
| WO-2020249664-A1 | SULFONYLUREA DERIVATIVES AND USES THEREOF | NodThera Limited (GB) | 2020-12-17 | — | — | WO | disclosed |
| US-20170253607-A1 | LONG-ACTING HIV PROTEASE INHIBITOR | SHIONOGI & CO., LTD. (JP) | 2017-09-07 | — | — | US | disclosed |
| EP-3192794-A1 | SUSTAINED HIV PROTEASE INHIBITOR | Shionogi & Co., Ltd. (JP) | 2017-07-19 | — | — | EP | disclosed |
| US-8367696-B2 | Aza-bridged-ring compound | ASTELLAS PHARMA INC. (JP) | 2013-02-05 | — | — | US | disclosed |
| US-8367696-B2 | Aza-bridged-ring compound | ASTELLAS PHARMA INC. (JP) | 2013-02-05 | — | — | US | disclosed |
| US-8367696-B2 | Aza-bridged-ring compound | ASTELLAS PHARMA INC. (JP) | 2013-02-05 | — | — | US | disclosed |
| US-20100105658-A1 | AZA-BRIDGED-RING COMPOUND | ASTELLAS PHARMA INC. (JP) | 2010-04-29 | — | — | US | disclosed |
| US-20100105658-A1 | AZA-BRIDGED-RING COMPOUND | ASTELLAS PHARMA INC. (JP) | 2010-04-29 | — | — | US | disclosed |
| US-20100105658-A1 | AZA-BRIDGED-RING COMPOUND | ASTELLAS PHARMA INC. (JP) | 2010-04-29 | — | — | US | disclosed |
| EP-2119716-A1 | AZA-BRIDGED-RING COMPOUND | Astellas Pharma Inc. (JP) | 2009-11-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170253607-A1 | LONG-ACTING HIV PROTEASE INHIBITOR | CPN1, HAT1, PRSS1 | ALDH1A1 4195/4885KDM4E 1195/4885MAPT 4683/4885 |
| US-12624023-B2 | Sulfonylurea derivatives and uses thereof | PYCARD, NOD1, NLRP3 | ALDH1A1 561/4885KDM4E 3454/4885MAPT 4223/4885 |
| US-20100105658-A1 | AZA-BRIDGED-RING COMPOUND | CHRM3, CHRM1, CHRM2 | ALDH1A1 2006/4885KDM4E 1245/4885MAPT 4405/4885 |
| US-20230083495-A1 | SULFONYLUREA DERIVATIVES AND USES THEREOF | IL1B, NOD1, IL1A | ALDH1A1 188/4885KDM4E 3522/4885MAPT 4413/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.