Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | G6PD | P11413 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3322365 | 0.80 | MAPT (0.56) | MAPTMAPK1ALDH1A1MEN1KMT2A | |
| SCHEMBL9655293 | 0.75 | MAPT (0.41) | MAPTMAPK1ALDH1A1MEN1KMT2A | |
| SCHEMBL2402093 | 0.73 | GPR35 (0.61) | MAPTMAPK1ALDH1A1MEN1KMT2A | |
| SCHEMBL3337954 | 0.73 | MAPT (0.48) | MAPTMAPK1ALDH1A1MEN1KMT2A | |
| SCHEMBL25723245 | 0.72 | MAPK1 (0.50) | MAPTMAPK1ALDH1A1MEN1KMT2A | |
| SCHEMBL9657631 | 0.71 | MAPT (0.56) | MAPTMAPK1ALDH1A1MEN1KMT2A | |
| SCHEMBL11796350 | 0.71 | MAPT (0.56) | MAPTMAPK1ALDH1A1MEN1KMT2A | |
| SCHEMBL4745055 | 0.71 | MAPT (0.56) | MAPTMAPK1ALDH1A1MEN1KMT2A | |
| SCHEMBL20970479 | 0.71 | ALDH1A1 (0.50) | MAPTMAPK1ALDH1A1MEN1KMT2A | |
| SCHEMBL25272394 | 0.71 | ALDH1A1 (0.46) | MAPTMAPK1ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1387661-B1 | TWO-PART AQUEOUS COMPOSITION FOR OXIDATIVE COLORATION OF HAIR | P & G CLAIROL INC (US) | 2007-01-24 | — | — | EP | disclosed |
| EP-1039876-B1 | DIRECT HAIR DYE COMPOSITIONS AND METHODS CONTAINING NOVEL ANTHRAQUINONE MIXTURES | P & G CLAIROL INC (US) | 2006-06-07 | — | — | EP | disclosed |
| EP-1387661-A4 | TWO-PART AQUEOUS COMPOSITION FOR OXIDATIVE COLORATION OF HAIR | P & G CLAIROL INC (US) | 2005-01-26 | — | — | EP | disclosed |
| EP-1039876-A4 | DIRECT HAIR DYE COMPOSITIONS AND METHODS CONTAINING NOVEL ANTHRAQUINONE MIXTURES | P & G CLAIROL INC (US) | 2005-01-19 | — | — | EP | disclosed |
| US-6764523-B2 | OXIDATIVE HAIR DYE FORMULATION CONSISTS OF 50% BY WEIGHT OF WATER, A TINCTORIAL EFFECTIVE AMOUNT OF A PRIMARY DYE INTERMEDIAE, A COUPLER, AND A HAIR CONDITIONER WHICH ISHYDROXYPROPYL BISISOSTEARAMIDOPROPYLDIMMONIUM CHLORIDE | THE PROCTER & GAMBLE COMPANY | 2004-07-20 | — | — | US | disclosed |
| EP-1387661-A1 | TWO-PART AQUEOUS COMPOSITION FOR OXIDATIVE COLORATION OF HAIR | P & G-Clairol, Inc. (US) | 2004-02-11 | — | — | EP | disclosed |
| US-6562080-B2 | 2-arylaminomethyl-4-aminophenols; light fastness, fastness to shampooing, fastness to permanent wave treatment | CLAIROL INCORPORATED | 2003-05-13 | — | — | US | disclosed |
| US-6521761-B2 | For coloring hair | CLAIROL INCORPORATED | 2003-02-18 | — | — | US | disclosed |
| US-20030005526-A1 | Two-part aqueous composition for oxidative coloration of hair | CLAIROL INCORPORATED | 2003-01-09 | — | — | US | disclosed |
| US-20020194683-A1 | Two-part aqueous composition for oxidative coloration of hair | WELLA OPERATIONS US, LLC | 2002-12-26 | — | — | US | disclosed |
| WO-2002092035-A1 | TWO-PART AQUEOUS COMPOSITION FOR OXIDATIVE COLORATION OF HAIR | P & G-CLAIROL, INC. (US) | 2002-11-21 | — | — | WO | disclosed |
| US-20020144355-A1 | Primary intermediates for oxidative coloration of hair | WELLA OPERATIONS US, LLC | 2002-10-10 | — | — | US | disclosed |
| US-6461391-B1 | Primary intermediates for oxidative coloration of hair | CLAIROL INCORPORATED | 2002-10-08 | — | — | US | disclosed |
| US-20020106341-A1 | PRIMARY INTERMEDIATES FOR OXIDATIVE COLORATION OF HAIR | WELLA OPERATIONS US, LLC | 2002-08-08 | — | — | US | disclosed |
| EP-1039876-A1 | DIRECT HAIR DYE COMPOSITIONS AND METHODS CONTAINING NOVEL ANTHRAQUINONE MIXTURES | Bristol-Myers Squibb Company (US) | 2000-10-04 | — | — | EP | disclosed |
| US-5961664-A | THREE 1,4-HYDROXYALKYLAMINO-ANTHRAQUINONE DERIVATIVES, WHEREIN TWO OF THE ANTHRAQUINONE COMPOUNDS IN THE MIXTURE ARE SYMMETRIC AND THE OTHER ANTHRAQUINONE COMPOUND IS ASYMMETRIC, AND WHEREIN EACH OF THE ANTHRAQUINONE COMPOUNDS HAS SIMILAR | BRISTOL-MYERS SQUIBB COMPANY (US) | 1999-10-05 | — | — | US | disclosed |
| WO-1999002124-A2 | DIRECT HAIR DYE COMPOSITIONS AND METHODS CONTAINING NOVEL ANTHRAQUINONE MIXTURES | BRISTOL-MYERS SQUIBB COMPANY (US) | 1999-01-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020144355-A1 | Primary intermediates for oxidative coloration of hair | CYC1, CBR1, CBR3 | MAPT 4479/4885MAPK1 513/4885ALDH1A1 7/4885 |
| US-20030005526-A1 | Two-part aqueous composition for oxidative coloration of hair | LPO, SQOR, CYB5R3 | MAPT 1971/4885MAPK1 3794/4885ALDH1A1 589/4885 |
| US-20020106341-A1 | PRIMARY INTERMEDIATES FOR OXIDATIVE COLORATION OF HAIR | CYC1, MT-CO1, PYCR1 | MAPT 4698/4885MAPK1 423/4885ALDH1A1 61/4885 |
| US-20020194683-A1 | Two-part aqueous composition for oxidative coloration of hair | LPO, SQOR, GPX4 | MAPT 2151/4885MAPK1 2737/4885ALDH1A1 376/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.