Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | ERN1 | O75460 | 1/20 | 0.35 |
| ▸ | AHR | P35869 | 2/20 | 0.34 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2049049 | 0.93 | CYP2A6 (0.48) | CYP2A6ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL2097335 | 0.85 | ALDH1A1 (0.59) | ALDH1A1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL29434184 | 0.85 | ALDH1A1 (0.59) | ALDH1A1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL5930707 | 0.81 | CYP2A6 (0.54) | CYP2A6ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL5930710 | 0.81 | CYP2A6 (0.54) | CYP2A6ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL28366291 | 0.80 | ALDH1A1 (0.53) | ALDH1A1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL29434157 | 0.78 | ALDH1A1 (0.56) | CYP2A6ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL2098638 | 0.78 | ALDH1A1 (0.56) | CYP2A6ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL3156949 | 0.77 | RELA (0.54) | CYP2A6ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL30343618 | 0.77 | ALDH1A1 (0.56) | CYP2A6ALDH1A1MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113166324-B | Thermosetting resin composition | 日产化学株式会社 | 2024-11-22 | — | — | CN | claimed |
| US-7145005-B2 | 2-(6-{2-[(2R)-2-Methyl-1-pyrrolidin-1-yl]-ethyl}-2-naphthalen-2-yl)-2H-pyridazin-3-one salts and their preparation | ABBOTT LABORATORIES (US) | 2006-12-05 | — | — | US | claimed |
| US-20050256127-A1 | 2-(6-{2-[(2R)-2-methyl-1-pyrrolidin-1-yl]-ethyl}-2-naphthalen-2-yl)-2H-pyridazin-3-one salts and their preparation | ABBVIE INC. | 2005-11-17 | — | — | US | claimed |
| US-20250224645-A1 | ELECTROPHORETIC MEDIUM COMPRISING PARTICLES HAVING A PIGMENT CORE AND A POLYMERIC SHELL | E INK CORPORATION | 2025-07-10 | — | — | US | disclosed |
| CN-113166324-B | Thermosetting resin composition | 日产化学株式会社 | 2024-11-22 | — | — | CN | disclosed |
| WO-2023215514-A2 | BIOLUMINESCENCE-TRIGGERED PHOTOCATALYTIC LABELING | PROMEGA CORPORATION (US) | 2023-11-09 | — | — | WO | disclosed |
| CN-115197053-B | Dihalocyclopropane derivative capable of releasing acid as well as preparation method and application thereof | 中山大学 | 2023-08-22 | — | — | CN | disclosed |
| CN-115197053-A | Dihalogen cyclopropane derivative capable of releasing acid and preparation method and application thereof | 中山大学 | 2022-10-18 | — | — | CN | disclosed |
| CN-113166324-A | Thermosetting resin composition | 日产化学株式会社 | 2021-07-23 | — | — | CN | disclosed |
| EP-3752571-A1 | OIL BINDER | SUMTEQ GmbH (DE) | 2020-12-23 | — | — | EP | disclosed |
| US-20200354220-A1 | COMPOSITE MATERIALS COMPRISING MECHANICAL LIGANDS | NANOCORE APS (DK) | 2020-11-12 | — | — | US | disclosed |
| US-20130119355-A1 | STYRYL-BASED COMPOUND, COMPOSITION CONTAINING STYRYL-BASED COMPOUND, AND ORGANIC LIGHT EMITTING DIODE INCLUDING STYRYL-BASED COMPOUND | SAMSUNG DISPLAY CO., LTD. (KR) | 2013-05-16 | — | — | US | disclosed |
| WO-2011072257-A2 | AMYLOID BINDING AGENTS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2011-06-16 | — | — | WO | disclosed |
| US-20100121055-A1 | PROCESSES FOR PREPARING (R)-2-METHYLPYRROLIDINE AND (S)-2-METHYLPYRROLIDINE AND TARTRATE SALTS THEREOF | CEPHALON, INC. (US) | 2010-05-13 | — | — | US | disclosed |
| CN-101679237-A | The method of preparation (R)-2-crassitude and (S)-2-crassitude and tartrate thereof | CEPHALON INC | 2010-03-24 | — | — | CN | disclosed |
| EP-2152669-A1 | PROCESSES FOR PREPARING (R)-2-METHYLPYRROLIDINE AND (S)-2-METHYLPYRROLIDINE AND TARTRATE SALTS THEREOF | Cephalon, Inc. (US) | 2010-02-17 | — | — | EP | disclosed |
| WO-2009130475-A1 | SUBSTITUTED THIOPHENECARBOXAMIDES AS IKK-BETA SERINE-, THREONINE-PROTEIN KINASE INHIBITORS | CHROMA THERAPEUTICS LTD., (GB) | 2009-10-29 | — | — | WO | disclosed |
| WO-2008137087-A1 | PROCESSES FOR PREPARING (R)-2-METHYLPYRROLIDINE AND (S)-2-METHYLPYRROLIDINE AND TARTRATE SALTS THEREOF | CEPHALON, INC. (US) | 2008-11-13 | — | — | WO | disclosed |
| US-7145005-B2 | 2-(6-{2-[(2R)-2-Methyl-1-pyrrolidin-1-yl]-ethyl}-2-naphthalen-2-yl)-2H-pyridazin-3-one salts and their preparation | ABBOTT LABORATORIES (US) | 2006-12-05 | — | — | US | disclosed |
| US-20050256127-A1 | 2-(6-{2-[(2R)-2-methyl-1-pyrrolidin-1-yl]-ethyl}-2-naphthalen-2-yl)-2H-pyridazin-3-one salts and their preparation | ABBVIE INC. | 2005-11-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100121055-A1 | PROCESSES FOR PREPARING (R)-2-METHYLPYRROLIDINE AND (S)-2-METHYLPYRROLIDINE AND TARTRATE SALTS THEREOF | TPMT, SPR, QDPR | CYP2A6 1350/4885ALDH1A1 1386/4885MEN1 2694/4885 |
| US-20050256127-A1 | 2-(6-{2-[(2R)-2-methyl-1-pyrrolidin-1-yl]-ethyl}-2-naphthalen-2-yl)-2H-pyridazin-3-one salts and their preparation | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, CYP2J2, NUP188 | CYP2A6 238/4885ALDH1A1 2085/4885MEN1 2394/4885 |
| US-20130119355-A1 | STYRYL-BASED COMPOUND, COMPOSITION CONTAINING STYRYL-BASED COMPOUND, AND ORGANIC LIGHT EMITTING DIODE INCLUDING STYRYL-BASED COMPOUND | OCIAD1, MAP1LC3B, ELOVL1 | CYP2A6 2305/4885ALDH1A1 87/4885MEN1 3869/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.