SCHEMBL3322916

SCHEMBL3322916

CCc1ccc(OC(C)OCCOc2cc3ccccc3cc2OC)cc1

nearest known ligand 0.39

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 1/20 0.39
DRD4 P21917 1/20 0.39
L3MBTL1 Q9Y468 2/20 0.38
NPSR1 Q6W5P4 1/20 0.38
KDM4E B2RXH2 1/20 0.38
CYP1A2 P05177 1/20 0.36
CYP2A6 P11509 1/20 0.36
SIGMAR1 Q99720 5/20 0.36
PPARG P37231 2/20 0.36
PPARA Q07869 2/20 0.36
PDE10A Q9Y233 2/20 0.36
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
MAPT P10636 1/20 0.35
HPGD P15428 1/20 0.35
ATM Q13315 1/20 0.35
PDGFRB P09619 1/20 0.34
PDGFRA P16234 1/20 0.34
PPARD Q03181 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3297979 0.85 GPR84 (0.43) L3MBTL1NPSR1KDM4ESIGMAR1PPARG
SCHEMBL3299018 0.82 HTR1B (0.48)
SCHEMBL3321919 0.82 CYP2D6 (0.40) L3MBTL1NPSR1KDM4ECYP1A2PPARG
SCHEMBL3325898 0.80 NQO1 (0.34)
SCHEMBL3322408 0.79 ALDH1A1 (0.39) KDM4EPPARGPPARAMAPTHPGD
SCHEMBL3326703 0.78 NPSR1 (0.46) L3MBTL1NPSR1CYP1A2CYP2A6MEN1
SCHEMBL3321951 0.78 ADRB2 (0.46) KDM4EMEN1KMT2A
SCHEMBL3326537 0.77 CYP1A2 (0.49) KDM4ECYP1A2CYP2A6PPARGPPARA
SCHEMBL3323842 0.76 CHRNB2 (0.44) L3MBTL1KDM4ECYP1A2PPARGPPARA
SCHEMBL14287836 0.76 LTA4H (0.51) L3MBTL1KDM4EPPARGPPARAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120003585-A1 ACTINIC-RAY- OR RADIATION-SENSITIVE RESIN COMPOSITION AND METHOD OF FORMING PATTERN USING THE COMPOSITION FUJIFILM CORPORATION (JP) 2012-01-05 US disclosed