Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTSR1 | P30989 | 10/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.50 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.50 |
| ▸ | IKBKB | O14920 | 1/20 | 0.48 |
| ▸ | HTR6 | P50406 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3193084 | 1.00 | NTSR1 (0.59) | NTSR1ALDH1A1MAPTSERPINE1NR1I2 | |
| SCHEMBL3194968 | 0.90 | NTSR1 (0.60) | NTSR1SERPINE1NR1I2 | |
| SCHEMBL3193765 | 0.88 | NTSR1 (0.70) | NTSR1 | |
| SCHEMBL3204698 | 0.88 | NR1I2 (0.53) | NTSR1ALDH1A1MAPTSERPINE1NR1I2 | |
| SCHEMBL3206680 | 0.86 | NTSR1 (0.53) | NTSR1SERPINE1HTR6 | |
| SCHEMBL3201141 | 0.81 | NTSR1 (0.75) | NTSR1 | |
| SCHEMBL3196667 | 0.80 | NTSR1 (0.79) | NTSR1ALDH1A1MAPT | |
| SCHEMBL3193347 | 0.79 | CA2 (0.49) | NTSR1ALDH1A1SERPINE1NR1I2 | |
| SCHEMBL3193462 | 0.79 | SERPINE1 (0.53) | ALDH1A1SERPINE1NR1I2 | |
| SCHEMBL3195444 | 0.78 | NR1I2 (0.63) | ALDH1A1SERPINE1NR1I2IKBKBHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100137363-A1 | Substituted Indoles And Methods Of Their Use | WYETH LLC (US) | 2010-06-03 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100137363-A1 | Substituted Indoles And Methods Of Their Use | INMT, AANAT, IDO2 | NTSR1 411/4885ALDH1A1 337/4885MAPT 2106/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.