SCHEMBL3328706

SCHEMBL3328706

CC(O)S(=O)(=O)c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.48
SMN1; SMN2 Q16637 3/20 0.48
HTR6 P50406 1/20 0.46
PSIP1 O75475 1/20 0.44
CA1 P00915 3/20 0.44
CA2 P00918 3/20 0.44
CA12 O43570 2/20 0.44
CA9 Q16790 2/20 0.44
KDM4E B2RXH2 3/20 0.43
MMP1 P03956 1/20 0.43
MMP2 P08253 1/20 0.43
MMP9 P14780 1/20 0.43
MMP8 P22894 1/20 0.43
MMP13 P45452 1/20 0.43
ALDH1A1 P00352 4/20 0.42
TDP1 Q9NUW8 3/20 0.42
HSD17B10 Q99714 2/20 0.42
CA3 P07451 1/20 0.42
CA4 P22748 1/20 0.42
CA6 P23280 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29741753 0.82 LMNA (0.46) TSHRSMN1; SMN2HTR6PSIP1CA1
SCHEMBL778854 0.80 HTR6 (0.50) TSHRSMN1; SMN2HTR6PSIP1CA1
SCHEMBL4327138 0.80 HTR6 (0.50) TSHRSMN1; SMN2HTR6PSIP1CA1
SCHEMBL5664473 0.80 MMP2 (0.50) TSHRHTR6MMP1MMP2MMP9
SCHEMBL5335059 0.79 GAA (0.52) SMN1; SMN2CA1CA2CA12CA9
SCHEMBL10767053 0.79 SMN1; SMN2 (0.41) TSHRSMN1; SMN2HTR6PSIP1CA1
SCHEMBL3328703 0.78 HTR6 (0.48) TSHRSMN1; SMN2HTR6PSIP1CA1
SCHEMBL10650374 0.78 MMP2 (0.40) CA1CA2CA12CA9KDM4E
SCHEMBL28902110 0.77 TSHR (0.70) TSHRSMN1; SMN2HTR6PSIP1CA1
SCHEMBL7758469 0.77 TSHR (0.52) TSHRSMN1; SMN2HTR6CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2003050094-A1 REACTIVE LIQUID POLYMER CROSSLINKING AGENT AND PROCESS FOR PREPARATION LCB WORLDWIDE INC. (US) 2003-06-19 WO claimed
EP-0602914-B1 Ink compositions for ink jet printing XEROX CORP (US) 1997-11-12 EP claimed
US-5300143-A Water soluble dye, sulfone, and amide or cyclic amine XEROX CORPORATION (US) 1994-04-05 US claimed
US-20240241440-A1 POLYMER, PHOTORESIST COMPOSITIONS INCLUDING THE SAME, AND PATTERN FORMATION METHODS U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2024-07-18 US disclosed
CN-118287092-A Sulfur-resistant catalyst for nitro catalytic hydrogenation and preparation method and application thereof 大连理工大学 2024-07-05 CN disclosed
US-20230212212-A1 PROCESSES FOR PREPARING OLIGONUCLEOTIDES SHANGHAI STA PHARMACEUTICAL R&D CO., LTD. (CN) 2023-07-06 US disclosed
EP-4182315-A1 PROCESSES FOR PREPARING OLIGONUCLEOTIDES Changzhou Syntheall Pharmaceuticals Co., Ltd. (CN) 2023-05-24 EP disclosed
WO-2022006871-A1 PROCESSES FOR PREPARING OLIGONUCLEOTIDES CHANGZHOU SYNTHEALL PHARMACEUTICALS CO., LTD. (CN) 2022-01-13 WO disclosed
CN-106496367-A Catalytic component and its preparation and application for olefinic polymerization 中国石油化工股份有限公司 2017-03-15 CN disclosed
CN-103509135-B Olefin polymerization catalyst component, preparation method and application thereof CHINA PETROLEUM & CHEMICAL 2015-07-22 CN disclosed
EP-2177519-B1 TETRAZOYLOXIME DERIVATIVE AND PLANT DISEASE CONTROL AGENT NIPPON SODA CO (JP) 2015-05-27 EP disclosed
EP-0382185-B1 Carbostyril derivatives OTSUKA PHARMA CO LTD (JP) 1994-06-15 EP disclosed
US-5300143-A Water soluble dye, sulfone, and amide or cyclic amine XEROX CORPORATION (US) 1994-04-05 US disclosed
WO-1994001113-A1 OXYTOCIN ANTAGONIST OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) 1994-01-20 WO disclosed
US-5225402-A Vasopressin antagonist, vasodilation, hypotensive, diuretics and anticoagulants OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1993-07-06 US disclosed
US-4754071-A Process for preparing aryl hydroxyethyl sulfones HOECHST AKTIENGESELLSCHAFT (DE) 1988-06-28 US disclosed
US-4695639-A Thiazole derivatives TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1987-09-22 US disclosed
EP-0115770-B1 THIAZOLE DERIVATIVES Takeda Chemical Industries, Ltd. (JP) 1987-07-22 EP disclosed
EP-0163996-A1 2,2-Dimethyl-3-formylcyclopropanes and process for their preparation BAYER AG (DE) 1985-12-11 EP disclosed
US-4157915-A (2-BENZENESULFONYL)-ETHOXYCARBONYLAMINO-ANILINE COMPOUND AS THE PRECURSOR FUJI PHOTO FILM CO., LTD. (JP) 1979-06-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230212212-A1 PROCESSES FOR PREPARING OLIGONUCLEOTIDES XRN2, UPF1, NSUN2 TSHR 2967/4885SMN1; SMN2 127/4885HTR6 4699/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.