Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | NAAA | Q02083 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13949542 | 0.87 | MEN1 (0.39) | MEN1KMT2AEPHX2HSD11B1ALDH1A1 | |
| SCHEMBL3322539 | 0.83 | ALDH1A1 (0.41) | HSD11B1HPGDALDH1A1LMNAP2RX7 | |
| SCHEMBL1769926 | 0.81 | CYP17A1 (0.52) | MEN1KMT2AHSD11B1CYP17A1CYP19A1 | |
| SCHEMBL1770371 | 0.77 | ALDH1A1 (0.40) | MEN1KMT2AHSD11B1HPGDCYP17A1 | |
| SCHEMBL3322239 | 0.74 | MEN1 (0.48) | MEN1KMT2AEPHX2HSD11B1HPGD | |
| SCHEMBL10349958 | 0.74 | ALDH1A1 (0.42) | MEN1KMT2AHSD11B1ALDH1A1HSP90AA1 | |
| SCHEMBL1769997 | 0.74 | HSD11B1 (0.60) | MEN1KMT2AHSD11B1CYP17A1CYP19A1 | |
| SCHEMBL3321390 | 0.73 | MEN1 (0.47) | MEN1KMT2AEPHX2HSD11B1HPGD | |
| SCHEMBL13778162 | 0.72 | LMNA (0.48) | MEN1KMT2AEPHX2ALDH1A1LMNA | |
| SCHEMBL12649171 | 0.71 | ALDH1A1 (0.35) | MEN1KMT2AHSD11B1CYP17A1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100120789-A1 | Compound | STERIX LIMITED (GB) | 2010-05-13 | — | — | US | disclosed |
| US-20100120789-A1 | Compound | STERIX LIMITED (GB) | 2010-05-13 | — | — | US | disclosed |
| US-20090042929-A1 | 11-Beta-Hydroxysteroid Dehydrogenase Inhibitors | STERIX LIMITED (GB) | 2009-02-12 | — | — | US | disclosed |
| US-20090042929-A1 | 11-Beta-Hydroxysteroid Dehydrogenase Inhibitors | STERIX LIMITED (GB) | 2009-02-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090042929-A1 | 11-Beta-Hydroxysteroid Dehydrogenase Inhibitors | HSD3B1, HSD3B2, HSD11B1 | MEN1 3474/4885KMT2A 3083/4885EPHX2 481/4885 |
| US-20100120789-A1 | Compound | NR0B2, NR0B1, NR4A1 | MEN1 2608/4885KMT2A 2533/4885EPHX2 1653/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.