SCHEMBL14401296

SCHEMBL14401296

O=S(=O)(CI)c1ccccc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PSIP1 O75475 1/20 0.61
HTR6 P50406 1/20 0.50
HSD11B1 P28845 4/20 0.47
ALDH1A1 P00352 3/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
HSD17B10 Q99714 2/20 0.46
TDP1 Q9NUW8 1/20 0.46
CA12 O43570 1/20 0.46
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
CA3 P07451 1/20 0.46
CA4 P22748 1/20 0.46
CA6 P23280 1/20 0.46
CA5A P35218 1/20 0.46
CA7 P43166 1/20 0.46
PLA2G7 Q13093 1/20 0.46
CA9 Q16790 1/20 0.46
CA13 Q8N1Q1 1/20 0.46
CA14 Q9ULX7 1/20 0.46
CA5B Q9Y2D0 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3329009 0.81 PSIP1 (0.64) PSIP1HTR6HSD11B1ALDH1A1SMN1; SMN2
SCHEMBL6757831 0.80 PSIP1 (0.56) PSIP1HTR6HSD11B1ALDH1A1SMN1; SMN2
SCHEMBL777601 0.78 PSIP1 (0.67) PSIP1HTR6HSD11B1ALDH1A1SMN1; SMN2
SCHEMBL64761 0.78 PSIP1 (0.67) PSIP1HTR6HSD11B1ALDH1A1SMN1; SMN2
SCHEMBL2454944 0.77 PSIP1 (0.58) PSIP1HTR6HSD11B1ALDH1A1SMN1; SMN2
SCHEMBL17838799 0.77 PSIP1 (0.52) PSIP1HTR6HSD11B1ALDH1A1CA2
SCHEMBL180713 0.76 PSIP1 (1.00) PSIP1HTR6HSD11B1ALDH1A1SMN1; SMN2
SCHEMBL14347652 0.75 PSIP1 (0.56) PSIP1HTR6HSD11B1ALDH1A1SMN1; SMN2
SCHEMBL14393403 0.75 ENPP2 (0.50) PSIP1ALDH1A1GAA
SCHEMBL14544901 0.75 MMP2 (0.45) HSD11B1ALDH1A1CA1CA2MMP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100335486-C Preparation method of [(phenyl sulfonyl) difluoro methyl] trimethyl silane SHANGHAI INST ORGANIC CHEM (CN) 2007-09-05 CN claimed
CN-122036555-A Trans-6, 7-disubstituted bicyclo [3.1.1] heptane and preparation method thereof 山东大学 2026-05-15 CN disclosed
CN-117088909-A Method for producing aryltrimethylstannane compound 上海致同建设工程科技有限公司 2023-11-21 CN disclosed
WO-2021078174-A1 CHIRAL SULFUR OXIDE-CONTAINING ARYL FORMAMIDE COMPOUND AND SALT THEREOF, PREPARATION METHOD THEREFOR, HERBICIDAL COMPOSITION, AND APPLICATION 青岛清原化合物有限公司 2021-04-29 WO disclosed
EP-2292779-B1 Adeno-associated virus (AAV) clades, sequences, vectors containing same, and uses thereof UNIV PENNSYLVANIA (US) 2016-11-16 EP disclosed
US-8367713-B2 Inhibition and dispersion of bacterial biofilms with imidazole-triazole derivatives NORTH CAROLINA STATE UNIVERSITY (US) 2013-02-05 US disclosed
CN-101415716-B Condensed imidazole derivatives as aldosterone synthase inhibitors SPEEDEL EXPERIMENTA AG 2012-12-12 CN disclosed
CN-101421277-A Imidazo compounds SPEEDEL EXPERIMENTA AG (CH) 2009-04-29 CN disclosed
CN-101421278-A Condensed imidazole derivatives as aldosterone synthase inhibitors SPEEDEL EXPERIMENTA AG (CH) 2009-04-29 CN disclosed
CN-101415716-A Condensed imidazole derivatives as aldosterone synthase inhibitors SPEEDEL EXPERIMENTA AG (CH) 2009-04-22 CN disclosed
WO-2007119001-A2 AMINOMETHYL PYRIDINE DERIVATIVES, METHOD FOR PREPARING SAME AND THERAPEUTIC USE THEREOF SANOFI-AVENTIS (FR) 2007-10-25 WO disclosed
EP-1844771-A2 Substituted indole acid derivatives as inhibitors of plasminogen activator inhibitor-1 (PAI-1) Wyeth (US) 2007-10-17 EP disclosed
EP-1397130-B1 SUBSTITUTED INDOLE ACID DERIVATIVES AS INHIBITORS OF PLASMINOGEN ACTIVATOR INHIBITOR-1 (PAI-1) WYETH CORP (US) 2007-07-25 EP disclosed
US-20070054939-A1 Thiazolypiperidine derivatives as mtp inhibitors MERCK PATNET GMBH (DE) 2007-03-08 US disclosed
US-20070010489-A1 Cellular accumulation of phosphonate analogs of hiv protease inhibitor compounds GILEAD SCIENCES, INC. 2007-01-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070054939-A1 Thiazolypiperidine derivatives as mtp inhibitors MTTP, CETP, APOB PSIP1 1727/4885HTR6 2602/4885HSD11B1 564/4885
US-20070010489-A1 Cellular accumulation of phosphonate analogs of hiv protease inhibitor compounds PPA1, PNP, PPME1 PSIP1 305/4885HTR6 4046/4885HSD11B1 2819/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.