Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.48 |
| ▸ | MGLL | Q99685 | 3/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.43 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.41 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.41 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2565168 | 0.85 | TSHR (0.52) | ALDH1A1TSHRAOC3MGLLCARM1 | |
| SCHEMBL21087535 | 0.79 | ALDH1A1 (0.48) | ALDH1A1TSHRAOC3MGLLCA2 | |
| SCHEMBL10900931 | 0.76 | ALDH1A1 (0.50) | ALDH1A1TSHRAOC3MGLLCA2 | |
| SCHEMBL21087587 | 0.74 | ALDH1A1 (0.43) | ALDH1A1TSHRAOC3MGLLCA2 | |
| SCHEMBL3271148 | 0.73 | TSHR (0.60) | ALDH1A1TSHRAOC3MGLLCA2 | |
| SCHEMBL134524 | 0.73 | TSHR (0.60) | ALDH1A1TSHRAOC3MGLLCA2 | |
| SCHEMBL21034084 | 0.72 | TSHR (0.48) | ALDH1A1TSHRAOC3MGLLCARM1 | |
| Ammonia Solution, Strong SCHEMBL1348044 | 0.71 | CNR2 (0.58) | ALDH1A1TSHRAOC3MGLLCA2 | |
| Hydrochloric Acid SCHEMBL2137949 | 0.71 | CNR2 (0.58) | ALDH1A1TSHRAOC3MGLLCA2 | |
| Fluoride SCHEMBL633879 | 0.71 | CNR2 (0.58) | ALDH1A1TSHRAOC3MGLLCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 371 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0732362-B1 | Silica reinforced rubber composition and use in tyres | GOODYEAR TIRE & RUBBER (US) | 1999-06-02 | — | — | EP | claimed |
| EP-0845493-A1 | Silica reinforced rubber composition and use in tires | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1998-06-03 | — | — | EP | claimed |
| US-5674932-A | THERMOMECHANICALLY MIXING A SULFUR VULCANIZABLE ELASTOMER, A PARTICULATE FILLER OF SILICA, ALUMINA OR SILICA-ALUMINA, AN ORGANOSILANE DISULFIDE/TRISULFIDE COMPOUND, ELEMENTAL SULFUR OR A SULFUR SOURCE AND AN ACCELERATOR | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1997-10-07 | — | — | US | claimed |
| US-5580919-A | ORGANOSILANE DISULFIDE COUPLER | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1996-12-03 | — | — | US | claimed |
| EP-0732362-A1 | Silica reinforced rubber composition and use in tyres | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1996-09-18 | — | — | EP | claimed |
| US-12570833-B2 | Silane functional amine compositions and their use in rubber | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2026-03-10 | — | — | US | disclosed |
| US-20260015490-A1 | Rubber Compositions Containing Phloroglucinolic Resins for Use in Tire Treads of Heavy Vehicles | SUMITOMO CHEMICAL ADVANCED TECH LLC D B A SUMIKA ELECTRONIC MATERIALS (US) | 2026-01-15 | — | — | US | disclosed |
| US-20250382436-A1 | REDUCING FORMALDEHYDE EMISSION FROM SILICA CONTAINING POLYMER NETWORK FORMATION | MOMENTIVE PERFORMANCE MAT INC (US) | 2025-12-18 | — | — | US | disclosed |
| EP-4554800-A1 | RUBBER COMPOSITIONS CONTAINING PHLOROGLUCINOLIC RESINS FOR USE IN TIRE TREADS OF HEAVY VEHICLES | Sumitomo Chemical Advanced Technologies LLC (US) | 2025-05-21 | — | — | EP | disclosed |
| WO-2025059191-A1 | SILANES FOR ADDRESSING VISCOSITY INSTABILITY IN SILANE TERMINATED SSBR | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2025-03-20 | — | — | WO | disclosed |
| US-20250084194-A1 | SILANES FOR ADDRESSING VISCOSITY INSTABILITY IN SILANE TERMINATED SSBR | MOMENTIVE PERFORMANCE MATERIALS INC. | 2025-03-13 | — | — | US | disclosed |
| CN-119546467-A | Rubber composition containing phloroglucinol resin for heavy vehicle tire tread | 住友化学先进技术有限责任公司即住化电子材料公司 | 2025-02-28 | — | — | CN | disclosed |
| US-6127468-A | MIXING A RUBBER, A BLOCKED MERCAPTOSILANE AND INORGANIC FILLER, MIXING THE ABOVE MIXTURE WITH A DEBLOCKING WITH THIURAM OR THIOSULFIDE COMPOUND | CK WITCO CORPORATION (US) | 2000-10-03 | — | — | US | disclosed |
| EP-0995775-A1 | Preparation of starch reinforced rubber | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2000-04-26 | — | — | EP | disclosed |
| EP-0994150-A1 | Preparation of reinforced rubber | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2000-04-19 | — | — | EP | disclosed |
| EP-0732362-B1 | Silica reinforced rubber composition and use in tyres | GOODYEAR TIRE & RUBBER (US) | 1999-06-02 | — | — | EP | disclosed |
| EP-0845493-A1 | Silica reinforced rubber composition and use in tires | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1998-06-03 | — | — | EP | disclosed |
| US-5674932-A | THERMOMECHANICALLY MIXING A SULFUR VULCANIZABLE ELASTOMER, A PARTICULATE FILLER OF SILICA, ALUMINA OR SILICA-ALUMINA, AN ORGANOSILANE DISULFIDE/TRISULFIDE COMPOUND, ELEMENTAL SULFUR OR A SULFUR SOURCE AND AN ACCELERATOR | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1997-10-07 | — | — | US | disclosed |
| US-5580919-A | ORGANOSILANE DISULFIDE COUPLER | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1996-12-03 | — | — | US | disclosed |
| EP-0732362-A1 | Silica reinforced rubber composition and use in tyres | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1996-09-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250084194-A1 | SILANES FOR ADDRESSING VISCOSITY INSTABILITY IN SILANE TERMINATED SSBR | SSB, PCNA, SPTAN1 | ALDH1A1 4020/4885TSHR 3646/4885AOC3 3976/4885 |
| US-12570833-B2 | Silane functional amine compositions and their use in rubber | CCNL2, RAD1, CCRL2 | ALDH1A1 2866/4885TSHR 3200/4885AOC3 48/4885 |
| US-20260015490-A1 | Rubber Compositions Containing Phloroglucinolic Resins for Use in Tire Treads of Heavy Vehicles | TST, RIF1, SORD | ALDH1A1 1331/4885TSHR 2223/4885AOC3 3991/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.