SCHEMBL334143

SCHEMBL334143

COc1ccc(C(OCCCO)(c2ccccc2)c2ccc(OC)cc2)cc1

nearest known ligand 0.51

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
SLC6A11 P48066 4/20 0.48
SLC6A1 P30531 2/20 0.48
KIF11 P52732 7/20 0.48
KCNH2 Q12809 1/20 0.48
MEN1 O00255 1/20 0.43
TP53 P04637 1/20 0.43
CYP1A2 P05177 1/20 0.43
CYP3A4 P08684 1/20 0.43
KMT2A Q03164 1/20 0.43
SLC6A12 P48065 1/20 0.43
SLC6A13 Q9NSD5 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8860350 0.95 SLC6A11 (0.47) SLC6A11SLC6A1KIF11KCNH2MEN1
SCHEMBL15318304 0.94 KIF11 (0.49) SLC6A11SLC6A1KIF11KCNH2
SCHEMBL1260569 0.94 SLC6A11 (0.46) SLC6A11SLC6A1KIF11KCNH2MEN1
SCHEMBL6849984 0.94 SLC6A11 (0.46) SLC6A11SLC6A1KIF11KCNH2MEN1
SCHEMBL887485 0.94 SLC6A11 (0.46) SLC6A11SLC6A1KIF11KCNH2MEN1
SCHEMBL27051202 0.94 SLC6A11 (0.46) SLC6A11SLC6A1KIF11KCNH2MEN1
SCHEMBL13427508 0.94 SLC6A11 (0.46) SLC6A11SLC6A1KIF11KCNH2MEN1
SCHEMBL2494966 0.94 SLC6A11 (0.43) SLC6A11SLC6A1MEN1TP53CYP1A2
SCHEMBL6570212 0.91 SLC6A11 (0.47) SLC6A11SLC6A1KIF11KCNH2MEN1
SCHEMBL2490410 0.90 SLC6A11 (0.50) SLC6A11SLC6A1KIF11KCNH2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 80 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030129589-A1 DNA DIAGNOSTICS BASED ON MASS SPECTROMETRY SEQUENOM, INC. 2003-07-10 US claimed
US-20020042112-A1 DNA DIAGNOSTICS BASED ON MASS SPECTROMETRY SEQUENOM, INC. 2002-04-11 US claimed
EP-0954612-A2 DNA DIAGNOSTICS BASED ON MASS SPECTROMETRY SEQUENOM, INC. (US) 1999-11-10 EP claimed
WO-1998020166-A2 DNA DIAGNOSTICS BASED ON MASS SPECTROMETRY SEQUENOM, INC. (US) 1998-05-14 WO claimed
EP-4683716-A1 DNA NANODEVICES FOR SPECIFIC AND EFFICIENT DELIVERY OF FUNCTIONAL PAYLOADS TO THE CYTOPLASM AND METHODS OF THEIR USE Arizona Board of Regents on behalf of Arizona State University (US) 2026-01-28 EP disclosed
US-20250302995-A1 OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF SHIVALILA CHIKDU SHAKTI (US) 2025-10-02 US disclosed
EP-4522744-A1 OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF Wave Life Sciences Ltd. (SG) 2025-03-19 EP disclosed
CN-119452084-A Oligonucleotide compositions and methods thereof 波涛生命科学有限公司 2025-02-14 CN disclosed
WO-2024196422-A1 DNA NANODEVICES FOR SPECIFIC AND EFFICIENT DELIVERY OF FUNCTIONAL PAYLOADS TO THE CYTOPLASM AND METHODS OF THEIR USE ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2024-09-26 WO disclosed
WO-2023220440-A1 OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF WAVE LIFE SCIENCES LTD. (SG) 2023-11-16 WO disclosed
EP-3814494-B1 HIGH THROUGHPUT ASSEMBLY OF NUCLEIC ACID MOLECULES THERMO FISHER SCIENT GENEART GMBH (DE) 2023-11-01 EP disclosed
US-20210147830-A1 HIGH THROUGHPUT ASSEMBLY OF NUCLEIC ACID MOLECULES THERMO FISHER SCIENTIFIC GENEART GMBH (DE) 2021-05-20 US disclosed
WO-1998020020-A2 HIGH DENSITY IMMOBILIZATION OF NUCLEIC ACIDS SEQUENOM, INC. (US) 1998-05-14 WO disclosed
EP-0459176-B1 Oligophosphates with antiviral activity BAYER AG (DE) 1995-09-06 EP disclosed
US-5416203-A VIRICIDES NORTHWESTERN UNIVERSITY (US) 1995-05-16 US disclosed
US-5169842-A OLIGOPHOSPHATES WITH AN ANTIVIRAL ACTION BAYER AKTIENGESELLSCHAFT (DE) 1992-12-08 US disclosed
EP-0428707-A4 STEROID MODIFIED OLIGONUCLEOTIDES 1992-05-20 EP disclosed
EP-0459176-A2 Oligophosphates with antiviral activity BAYER AG (DE) 1991-12-04 EP disclosed
EP-0428707-A1 STEROID MODIFIED OLIGONUCLEOTIDES NORTHWESTERN UNIVERSITY (US) 1991-05-29 EP disclosed
WO-1990014822-A1 STEROID MODIFIED OLIGONUCLEOTIDES NORTHWESTERN UNIVERSITY (US) 1990-12-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250302995-A1 OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF ADAR, NSUN2, RNGTT SLC6A11 4777/4885SLC6A1 4770/4885KIF11 3613/4885
US-20020042112-A1 DNA DIAGNOSTICS BASED ON MASS SPECTROMETRY DNA2, DDB1, DNMT3A SLC6A11 3886/4885SLC6A1 4252/4885KIF11 1143/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.