Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | RECQL | P46063 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | NSD2 | O96028 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | GALK1 | P51570 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15517522 | 0.89 | SLC29A1 (0.35) | MAPTALDH1A1RECQLNPC1MITF | |
| SCHEMBL8756842 | 0.80 | ALDH1A1 (0.35) | MAPTALDH1A1RECQLL3MBTL1MEN1 | |
| SCHEMBL28549550 | 0.79 | ACHE (0.40) | MAPTALDH1A1RECQLMEN1KMT2A | |
| SCHEMBL3673241 | 0.79 | MEN1 (0.38) | MAPTALDH1A1RECQLMEN1KMT2A | |
| SCHEMBL28570427 | 0.76 | ACHE (0.46) | MAPTALDH1A1RECQLMEN1KMT2A | |
| SCHEMBL28562469 | 0.74 | ACHE (0.38) | MAPTALDH1A1RECQLBLMMEN1 | |
| SCHEMBL28553031 | 0.73 | ACHE (0.51) | MAPTALDH1A1MEN1KMT2AHPGD | |
| Trolamine SCHEMBL28076459 | 0.67 | MAPK1 (0.44) | MAPTALDH1A1RECQLHTTBLM | |
| SCHEMBL5179874 | 0.66 | ERBB2 (0.41) | MAPTALDH1A1RECQLBLMMEN1 | |
| SCHEMBL7833680 | 0.64 | ALDH1A1 (0.78) | MAPTALDH1A1RECQLNPC1MITF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9796730-B2 | Halogenated benzoxazines and their use | EBERHARD KARLS UNIVERSITAET TUEBINGEN MEDIZINISCHE FAKULTAET (DE) | 2017-10-24 | — | — | US | disclosed |
| EP-2890700-A1 | HALOGENATED BENZOXAZINES AND USE THEREOF | Eberhard Karls Universität Tübingen Medizinische Fakultät (DE) | 2015-07-08 | — | — | EP | disclosed |
| US-20150166572-A1 | HALOGENATED BENZOXAZINES AND THEIR USE | EBERHARD KARLS UNIVERSITAET TUEBINGEN MEDIZINISCHE FAKULTAET (DE) | 2015-06-18 | — | — | US | disclosed |
| WO-2014032732-A1 | HALOGENATED BENZOXAZINES AND USE THEREOF | EBERHARD KARLS UNIVERSITÄT TÜBINGEN MEDIZINISCHE FAKULTÄT (DE) | 2014-03-06 | — | — | WO | disclosed |
| US-20100162416-A1 | Multi-stage stem cell carcinogenesis | STEMLIFELINE, INC. (US) | 2010-06-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150166572-A1 | HALOGENATED BENZOXAZINES AND THEIR USE | XDH, BAZ1A, CYP4Z1 | MAPT 99/4885ALDH1A1 819/4885RECQL 1655/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.