Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MITF | O75030 | 1/20 | 0.34 |
| ▸ | NSD2 | O96028 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | GALK1 | P51570 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3341534 | 0.89 | MAPT (0.37) | HTTMAPTNPC1MITFNSD2 | |
| SCHEMBL28562469 | 0.85 | ACHE (0.38) | MAPTALDH1A1RECQLBLMACHE | |
| SCHEMBL8756842 | 0.78 | ALDH1A1 (0.35) | MAPTALDH1A1RECQLL3MBTL1ACHE | |
| SCHEMBL28549550 | 0.77 | ACHE (0.40) | MAPTALDH1A1RECQLACHEBACE1 | |
| SCHEMBL28570427 | 0.74 | ACHE (0.46) | MAPTALDH1A1RECQLACHEBACE1 | |
| SCHEMBL28553031 | 0.71 | ACHE (0.51) | MAPTALDH1A1ACHEBACE1 | |
| SCHEMBL3673241 | 0.69 | MEN1 (0.38) | MAPTALDH1A1RECQLERBB2 | |
| SCHEMBL21814508 | 0.67 | ALDH1A1 (0.34) | HTTMAPTALDH1A1RECQLRAB9A | |
| SCHEMBL15020301 | 0.67 | DNM1 (0.56) | HTTMAPTNPC1MITFNSD2 | |
| SCHEMBL28247119 | 0.66 | ACHE (0.44) | MAPTALDH1A1RECQLACHEBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9796730-B2 | Halogenated benzoxazines and their use | EBERHARD KARLS UNIVERSITAET TUEBINGEN MEDIZINISCHE FAKULTAET (DE) | 2017-10-24 | — | — | US | disclosed |
| US-9796730-B2 | Halogenated benzoxazines and their use | EBERHARD KARLS UNIVERSITAET TUEBINGEN MEDIZINISCHE FAKULTAET (DE) | 2017-10-24 | — | — | US | disclosed |
| EP-2890700-A1 | HALOGENATED BENZOXAZINES AND USE THEREOF | Eberhard Karls Universität Tübingen Medizinische Fakultät (DE) | 2015-07-08 | — | — | EP | disclosed |
| US-20150166572-A1 | HALOGENATED BENZOXAZINES AND THEIR USE | EBERHARD KARLS UNIVERSITAET TUEBINGEN MEDIZINISCHE FAKULTAET (DE) | 2015-06-18 | — | — | US | disclosed |
| US-20150166572-A1 | HALOGENATED BENZOXAZINES AND THEIR USE | EBERHARD KARLS UNIVERSITAET TUEBINGEN MEDIZINISCHE FAKULTAET (DE) | 2015-06-18 | — | — | US | disclosed |
| WO-2014032732-A1 | HALOGENATED BENZOXAZINES AND USE THEREOF | EBERHARD KARLS UNIVERSITÄT TÜBINGEN MEDIZINISCHE FAKULTÄT (DE) | 2014-03-06 | — | — | WO | disclosed |
| WO-2014032732-A1 | HALOGENATED BENZOXAZINES AND USE THEREOF | EBERHARD KARLS UNIVERSITÄT TÜBINGEN MEDIZINISCHE FAKULTÄT (DE) | 2014-03-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150166572-A1 | HALOGENATED BENZOXAZINES AND THEIR USE | XDH, BAZ1A, CYP4Z1 | SLC29A1 2045/4885HTT 62/4885MAPT 99/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.