Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.56 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.46 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.46 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4450105 | 0.87 | ALOX5 (0.56) | MAOBALOX5SMN1; SMN2L3MBTL1BCHE | |
| SCHEMBL10243525 | 0.75 | ALOX5 (0.54) | ALOX5SMN1; SMN2L3MBTL1BCHE | |
| SCHEMBL42302 | 0.75 | MAOB (1.00) | MAOBALDH1A1HTTSMN1; SMN2L3MBTL1 | |
| SCHEMBL334377 | 0.72 | NQO1 (0.44) | ALDH1A1SMN1; SMN2PARP10LMNA | |
| SCHEMBL22664704 | 0.72 | PGR (0.66) | MAOBALDH1A1HTTSMN1; SMN2L3MBTL1 | |
| SCHEMBL9126144 | 0.71 | MAOB (0.90) | MAOBALDH1A1HTTSMN1; SMN2L3MBTL1 | |
| SCHEMBL6337667 | 0.71 | MAOB (0.90) | MAOBALDH1A1HTTSMN1; SMN2L3MBTL1 | |
| SCHEMBL335260 | 0.71 | HRH1 (0.45) | ALOX5CYP1A2CYP2C19SLC6A3 | |
| SCHEMBL7713248 | 0.71 | ALOX5 (0.78) | ALOX5PTGS1PTGS2 | |
| SCHEMBL334955 | 0.70 | TRPM8 (0.52) | ALDH1A1HTTSMN1; SMN2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8097708-B2 | 10a-Azalide compound | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2012-01-17 | — | — | US | disclosed |