Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL333703 | 0.89 | ALDH1A1 (0.36) | ALDH1A1 | |
| SCHEMBL333719 | 0.82 | ALDH1A1 (0.31) | ALDH1A1LMNAHSD17B10 | |
| SCHEMBL703725 | 0.78 | ALDH1A1 (0.35) | ALDH1A1LMNAHSD17B10 | |
| SCHEMBL7634931 | 0.77 | THRB (0.47) | ALDH1A1HSD17B10 | |
| SCHEMBL333195 | 0.77 | — | — | |
| SCHEMBL334963 | 0.74 | ALDH1A1 (0.38) | ALDH1A1 | |
| SCHEMBL706117 | 0.73 | KDM4E (0.35) | ALDH1A1LMNAHSD17B10 | |
| SCHEMBL12345662 | 0.73 | — | — | |
| SCHEMBL703249 | 0.73 | KDM4E (0.35) | ALDH1A1LMNAHSD17B10 | |
| SCHEMBL334028 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 121 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113795499-B | Process for producing alkoxysilyl group-containing thiocarboxylate | 迈图高新材料公司 | 2024-03-19 | — | — | CN | claimed |
| US-10919920-B2 | Method for the manufacture of alkoxysilyl-containing thiocarboxylic acid esters | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2021-02-16 | — | — | US | claimed |
| US-20200347084-A1 | METHOD FOR THE MANUFACTURE OF ALKOXYSILYL-CONTAINING THIOCARBOXYLIC ACID ESTERS | MOMENTIVE PERFORMANCE MATERIALS INC. | 2020-11-05 | — | — | US | claimed |
| EP-1341843-B2 | MINERAL-FILLED ELASTOMER COMPOSITIONS | MOMENTIVE PERFORMANCE MAT INC (US) | 2016-03-23 | — | — | EP | claimed |
| EP-1560836-B1 | PROCESS FOR MANUFACTURE OF BLOCKED MERCAPTOSILANE COUPLING AGENTS | MOMENTIVE PERFORMANCE MAT INC (US) | 2015-12-30 | — | — | EP | claimed |
| EP-1669401-B1 | Tire with tread containing combination of specialized elastomer and coupling agent | GOODYEAR TIRE & RUBBER (US) | 2013-07-31 | — | — | EP | claimed |
| US-8097743-B2 | Process for manufacture of blocked mercaptosilane coupling agents | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2012-01-17 | — | — | US | claimed |
| US-20100190885-A1 | TIRE WITH RUBBER COMPONENT CONTAINING SILICA AND USE OF COMBINATION OF BLOCKED AND UNBLOCKED ALKOXYORGANOMERCAPTOSILANE COUPLING AGENTS | HUA KUO-CHIH | 2010-07-29 | — | — | US | claimed |
| EP-1491545-B1 | Method of preparing a composite of hydrophobated amorphous silica employing blocked mercaptoalkoxysilanes | GOODYEAR TIRE & RUBBER (US) | 2009-01-14 | — | — | EP | claimed |
| EP-0958298-B2 | BLOCKED MERCAPTOSILANE COUPLING AGENTS FOR FILLED RUBBERS | MOMENTIVE PERFORMANCE MAT INC (US) | 2008-10-22 | — | — | EP | claimed |
| EP-1341843-A2 | MINERAL-FILLED ELASTOMER COMPOSITIONS | Crompton Corporation (US) | 2003-09-10 | — | — | EP | claimed |
| EP-0958298-B1 | BLOCKED MERCAPTOSILANE COUPLING AGENTS FOR FILLED RUBBERS | CROMPTON CORP (US) | 2003-05-07 | — | — | EP | claimed |
| US-6528673-B2 | Reacting a mercaptosilane and a monoacid anhydride corresponding to a thioester group present in the desired product, or reacting alkali salt of a mercaptosilane with an acid anhydride or acid halide or transesterification | CROMPTON CORPORATION | 2003-03-04 | — | — | US | claimed |
| US-20020115767-A1 | Mineral-filled elastomer compositions | MOMENTIVE PERFORMANCE MATERIALS INC. | 2002-08-22 | — | — | US | claimed |
| US-20020099118-A1 | For use in tires, shoe soles | WITCO CORPORATION, A CORPORATION OF THE STATE OF DELAWARE | 2002-07-25 | — | — | US | claimed |
| US-6414061-B1 | CURABLE MIXTURE | CROMPTON CORPORATION | 2002-07-02 | — | — | US | claimed |
| WO-2002048256-A2 | MINERAL-FILLED ELASTOMER COMPOSITIONS | CROMPTON CORPORATION (US) | 2002-06-20 | — | — | WO | claimed |
| US-20020055646-A1 | Reacting a mercaptosilane and a monoacid anhydride corresponding to a thioester group present in the desired product, or reacting alkali salt of a mercaptosilane with an acid anhydride or acid halide or transesterification | WITCO CORPORATION | 2002-05-09 | — | — | US | claimed |
| EP-0958298-A1 | BLOCKED MERCAPTOSILANE COUPLING AGENTS FOR FILLED RUBBERS | WITCO CORPORATION (US) | 1999-11-24 | — | — | EP | claimed |
| WO-1999009036-A1 | BLOCKED MERCAPTOSILANE COUPLING AGENTS FOR FILLED RUBBERS | OSI SPECIALTIES, INC. (US) | 1999-02-25 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10919920-B2 | Method for the manufacture of alkoxysilyl-containing thiocarboxylic acid esters | TST, MPST, APEH | ALDH1A1 2154/4885LMNA 4244/4885HSD17B10 323/4885 |
| US-20200347084-A1 | METHOD FOR THE MANUFACTURE OF ALKOXYSILYL-CONTAINING THIOCARBOXYLIC ACID ESTERS | TST, MPST, APEH | ALDH1A1 2154/4885LMNA 4244/4885HSD17B10 323/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.