SCHEMBL334963

SCHEMBL334963

CC(=O)O[Si](CCCOC(C)=S)(OC(C)=O)OC(C)=O

nearest known ligand 0.38

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL333719 0.88 ALDH1A1 (0.31) ALDH1A1
SCHEMBL333703 0.83 ALDH1A1 (0.36) ALDH1A1
SCHEMBL703686 0.79 KDM4E (0.36) ALDH1A1
SCHEMBL704685 0.79 KDM4E (0.36) ALDH1A1
SCHEMBL143449 0.78 TSHR (0.53) ALDH1A1
SCHEMBL3899362 0.78 TSHR (0.39) ALDH1A1
SCHEMBL1231821 0.78 ALDH1A1 (0.35) ALDH1A1
SCHEMBL333701 0.78 LMNA (0.33)
SCHEMBL303979 0.77 KDM4E (0.40) ALDH1A1
SCHEMBL28347798 0.77 TSHR (0.51) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 279 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113795499-B Process for producing alkoxysilyl group-containing thiocarboxylate 迈图高新材料公司 2024-03-19 CN claimed
US-20220363873-A1 SILANE COUPLING AGENT COMPOSITION COMPRISING SILANE COMPOUND AND PROTEIN MODIFYING AGENT, AND RUBBER COMPOSITION COMPRISING THE SAME ENEOS CORPORATION (JP) 2022-11-17 US claimed
EP-3981610-A1 SILANE COUPLING AGENT COMPOSITION CONTAINING SILANE COMPOUND AND PROTEIN DENATURING AGENT, AND RUBBER COMPOSITION CONTAINING SAID COMPOSITION ENEOS Corporation (JP) 2022-04-13 EP claimed
EP-3962917-A1 METHOD FOR THE MANUFACTURE OF ALKOXYSILYL-CONTAINING THIOCARBOXYLIC ACID ESTERS Momentive Performance Materials Inc. (US) 2022-03-09 EP claimed
CN-113924335-A Silane coupling agent composition comprising silane compound and protein denaturing agent, and rubber composition comprising same 引能仕株式会社 2022-01-11 CN claimed
CN-113795499-A Process for producing alkoxysilyl group-containing thiocarboxylic ester 迈图高新材料公司 2021-12-14 CN claimed
US-10919920-B2 Method for the manufacture of alkoxysilyl-containing thiocarboxylic acid esters MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2021-02-16 US claimed
WO-2020223068-A1 METHOD FOR THE MANUFACTURE OF ALKOXYSILYL-CONTAINING THIOCARBOXYLIC ACID ESTERS MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2020-11-05 WO claimed
US-20200347084-A1 METHOD FOR THE MANUFACTURE OF ALKOXYSILYL-CONTAINING THIOCARBOXYLIC ACID ESTERS MOMENTIVE PERFORMANCE MATERIALS INC. 2020-11-05 US claimed
EP-1341843-B2 MINERAL-FILLED ELASTOMER COMPOSITIONS MOMENTIVE PERFORMANCE MAT INC (US) 2016-03-23 EP claimed
EP-1341843-A2 MINERAL-FILLED ELASTOMER COMPOSITIONS Crompton Corporation (US) 2003-09-10 EP claimed
EP-0958298-B1 BLOCKED MERCAPTOSILANE COUPLING AGENTS FOR FILLED RUBBERS CROMPTON CORP (US) 2003-05-07 EP claimed
US-6528673-B2 Reacting a mercaptosilane and a monoacid anhydride corresponding to a thioester group present in the desired product, or reacting alkali salt of a mercaptosilane with an acid anhydride or acid halide or transesterification CROMPTON CORPORATION 2003-03-04 US claimed
US-20020115767-A1 Mineral-filled elastomer compositions MOMENTIVE PERFORMANCE MATERIALS INC. 2002-08-22 US claimed
US-20020099118-A1 For use in tires, shoe soles WITCO CORPORATION, A CORPORATION OF THE STATE OF DELAWARE 2002-07-25 US claimed
US-6414061-B1 CURABLE MIXTURE CROMPTON CORPORATION 2002-07-02 US claimed
WO-2002048256-A2 MINERAL-FILLED ELASTOMER COMPOSITIONS CROMPTON CORPORATION (US) 2002-06-20 WO claimed
US-20020055646-A1 Reacting a mercaptosilane and a monoacid anhydride corresponding to a thioester group present in the desired product, or reacting alkali salt of a mercaptosilane with an acid anhydride or acid halide or transesterification WITCO CORPORATION 2002-05-09 US claimed
EP-0958298-A1 BLOCKED MERCAPTOSILANE COUPLING AGENTS FOR FILLED RUBBERS WITCO CORPORATION (US) 1999-11-24 EP claimed
WO-1999009036-A1 BLOCKED MERCAPTOSILANE COUPLING AGENTS FOR FILLED RUBBERS OSI SPECIALTIES, INC. (US) 1999-02-25 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10919920-B2 Method for the manufacture of alkoxysilyl-containing thiocarboxylic acid esters TST, MPST, APEH ALDH1A1 2154/4885
US-20200347084-A1 METHOD FOR THE MANUFACTURE OF ALKOXYSILYL-CONTAINING THIOCARBOXYLIC ACID ESTERS TST, MPST, APEH ALDH1A1 2154/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.