SCHEMBL3344111

SCHEMBL3344111

C=CCc1ccccc1[SiH](OCC)OCC

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 1/20 0.37
GABRB2 P47870 1/20 0.37
ALDH1A1 P00352 3/20 0.35
ADRA2C P18825 4/20 0.34
ADRB2 P07550 3/20 0.34
ADRB1 P08588 3/20 0.34
LMNA P02545 2/20 0.34
HTR1A P08908 2/20 0.34
ADRB3 P13945 1/20 0.34
SLC6A2 P23975 1/20 0.34
BDKRB2 P30411 1/20 0.34
SLC6A4 P31645 1/20 0.34
ADRA1A P35348 1/20 0.34
HTR2B P41595 1/20 0.34
KCNH2 Q12809 1/20 0.34
CYP1A2 P05177 1/20 0.34
CYP2D6 P10635 1/20 0.34
TSHR P16473 1/20 0.34
NFKB1 P19838 1/20 0.34
MAPT P10636 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3109867 0.82 GABRA1 (0.39) GABRA1GABRB2ALDH1A1ADRA2CADRB2
SCHEMBL4267871 0.80 MAPT (0.40) GABRA1GABRB2CYP2D6TSHRMAPT
SCHEMBL2961096 0.77 ALDH1A1 (0.33) ALDH1A1TSHR
SCHEMBL4081156 0.77 MAPT (0.31) MAPT
SCHEMBL1263437 0.77 TSHR (0.32) ALDH1A1LMNACYP1A2CYP2D6TSHR
SCHEMBL3482683 0.77 ADRA2A (0.33) ADRA2CHTR1ASLC6A2SLC6A4MAPT
SCHEMBL1262959 0.77 TSHR (0.33) GABRA1GABRB2LMNACYP1A2CYP2D6
SCHEMBL28730873 0.77 GABRA1 (0.40) GABRA1GABRB2ALDH1A1ADRA2CADRB2
SCHEMBL545114 0.76 GABRA1 (0.37) GABRA1GABRB2ALDH1A1ADRA2CADRB2
SCHEMBL28730875 0.76 GABRA1 (0.42) GABRA1GABRB2ALDH1A1ADRA2CADRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6126777-A AN AQUEOUS ADHESIVE USEFUL FOR BONDING VULCANIZABLE ELASTOMERIC RUBBER TO A SUBSTRATE, MADE FROM ALTEST ONE VINYL GROUP CONTAINING SILANE COMPOUND AND A POLYISOCYANATE; VULCANIZABLE; CURING; INCREASED SHELF-LIFE LORD CORPORATION (US) 2000-10-03 US claimed
CN-115181223-A Low-gloss matte auxiliary agent, preparation method thereof and formed body 铨盛聚碳科技股份有限公司 2022-10-14 CN disclosed
US-8968458-B2 Composition for resist underlayer film and process for producing same JSR CORPORATION (JP) 2015-03-03 US disclosed
US-8808446-B2 Composition for resist underlayer film and process for producing same JSR CORPORATION (JP) 2014-08-19 US disclosed
US-20100151384-A1 COMPOSITION FOR RESIST UNDERLAYER FILM AND PROCESS FOR PRODUCING SAME JSR CORPORATION (JP) 2010-06-17 US disclosed
US-20090050020-A1 COMPOSITION FOR RESIST UNDERLAYER FILM AND PROCESS FOR PRODUCING SAME JSR CORPORATION (JP) 2009-02-26 US disclosed
EP-1855159-A1 COMPOSITION FOR UNDERLAYER FILM OF RESIST AND PROCESS FOR PRODUCING THE SAME JSR Corporation (JP) 2007-11-14 EP disclosed
US-7291567-B2 Silica-based film, method of forming the same, composition for forming insulating film for semiconductor device, interconnect structure, and semiconductor device JSR CORPORATION (JP) 2007-11-06 US disclosed
US-20060024980-A1 Silica-based film, method of forming the same, composition for forming insulating film for semiconductor device, interconnect structure, and semiconductor device JSR CORPORATION (JP) 2006-02-02 US disclosed
EP-1619226-A1 Silica-based film, method of forming the same, composition for forming insulating film for semiconductor device, interconnect structure, and semiconductor device JSR Corporation (JP) 2006-01-25 EP disclosed
EP-0977791-A1 AQUEOUS SILANE ADHESIVE COMPOSITIONS Lord Corporation (US) 2000-02-09 EP disclosed
WO-1999042509-A1 AQUEOUS SILANE ADHESIVE COMPOSITIONS LORD CORPORATION (US) 1999-08-26 WO disclosed
EP-0280423-B1 HEAT ACTIVATED SILICON-BASED ADHESIVE LORD CORPORATION (US) 1992-08-12 EP disclosed
US-4857250-A One-extrusion method of making a shaped crosslinkable extruded polymeric product UNION CARBIDE CORPORATION (US) 1989-08-15 US disclosed
EP-0280423-A2 Heat activated silicon-based adhesive LORD CORPORATION (US) 1988-08-31 EP disclosed
EP-0163865-B1 ONE-EXTRUSION METHOD FOR MAKING A SHAPED CROSSLINKED POLYMERIC PRODUCT UNION CARBIDE CORPORATION (US) 1988-06-15 EP disclosed
EP-0235439-A1 Electrically conductive polymers and their production RAPRA TECHNOLOGY LIMITED (GB) 1987-09-09 EP disclosed
US-4690966-A BLEND OF OLEFINIC ORGANOSILANE, WATER AND ALUMINO ZIRCONIUM COMPLEX LORD CORPORATION (US) 1987-09-01 US disclosed
EP-0163865-A1 One-extrusion method for making a shaped crosslinked polymeric product UNION CARBIDE CORPORATION (US) 1985-12-11 EP disclosed
WO-1985004618-A1 ONE-EXTRUSION METHOD OF MAKING A SHAPED CROSSLINKABLE EXTRUDED POLYMERIC PRODUCT UNION CARBIDE CORPORATION (US) 1985-10-24 WO disclosed