SCHEMBL545114

SCHEMBL545114

C=CCc1ccccc1[SiH](Oc1ccccc1)Oc1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 1/20 0.37
GABRB2 P47870 1/20 0.37
KDM4E B2RXH2 3/20 0.33
ALDH1A1 P00352 3/20 0.33
AURKA O14965 1/20 0.33
DAPK3 O43293 1/20 0.33
MAP4K4 O95819 1/20 0.33
RET P07949 1/20 0.33
IGF1R P08069 1/20 0.33
MET P08581 1/20 0.33
PIM1 P11309 1/20 0.33
LTK P29376 1/20 0.33
KDR P35968 1/20 0.33
MAPK8 P45983 1/20 0.33
MAPK9 P45984 1/20 0.33
CDK8 P49336 1/20 0.33
CLK2 P49760 1/20 0.33
CDK9 P50750 1/20 0.33
CDK5 Q00535 1/20 0.33
ACVR1 Q04771 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3109867 0.79 GABRA1 (0.39) GABRA1GABRB2KDM4EALDH1A1HTR1A
SCHEMBL3344111 0.76 GABRA1 (0.37) GABRA1GABRB2KDM4EALDH1A1HTR1A
Benzene SCHEMBL28085432 0.72 GABRA1 (0.54) GABRA1GABRB2KDM4EALDH1A1AURKA
SCHEMBL28730875 0.72 GABRA1 (0.42) GABRA1GABRB2KDM4EALDH1A1HTR1A
SCHEMBL125206 0.72 GABRA1 (0.42) GABRA1GABRB2KDM4EALDH1A1HTR1A
SCHEMBL6841674 0.72 GABRA1 (0.47) GABRA1GABRB2KDM4EALDH1A1HTR1A
Hydrogen Peroxide SCHEMBL7819301 0.70 GABRA1 (0.58) GABRA1GABRB2KDM4EALDH1A1AURKA
Hydrogen Peroxide SCHEMBL10784213 0.70 GABRA1 (0.58) GABRA1GABRB2KDM4EALDH1A1AURKA
SCHEMBL173300 0.70 GABRA1 (0.56) GABRA1GABRB2KDM4EALDH1A1HTR1A
SCHEMBL29763626 0.70 GABRA1 (0.56) GABRA1GABRB2KDM4EALDH1A1HTR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10875879-B2 Compositions, synthesis, and uses of hydrolyzable silane modified cashew nut shell liquid derivatives CARDOLITE CORPORATION (US) 2020-12-29 US claimed
US-20190077815-A1 COMPOSITIONS, SYNTHESIS, AND USES OF HYDROLYZABLE SILANE MODIFIED CASHEW NUT SHELL LIQUID DERIVATIVES CARDOLITE CORPORATION 2019-03-14 US claimed
US-8110036-B2 Moisture curable oil and fat compositions and processes for preparing the same BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERISTY (US) 2012-02-07 US claimed
WO-2010042175-A1 MOISTURE-CURABLE OIL AND FAT COMPOSITIONS AND PROCESSES FOR PREPARING THE SAME MICHIGAN STATE UNIVERSITY (US) 2010-04-15 WO claimed
US-20100083871-A1 Moisture-curable oil and fat compositions and processes for preparing the same BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) 2010-04-08 US claimed
US-10875879-B2 Compositions, synthesis, and uses of hydrolyzable silane modified cashew nut shell liquid derivatives CARDOLITE CORPORATION (US) 2020-12-29 US disclosed
US-20190077815-A1 COMPOSITIONS, SYNTHESIS, AND USES OF HYDROLYZABLE SILANE MODIFIED CASHEW NUT SHELL LIQUID DERIVATIVES CARDOLITE CORPORATION 2019-03-14 US disclosed
EP-2994105-A2 CONSUMER PRODUCTS COMPRISING SILANE-MODIFIED OILS The Procter and Gamble Company (US) 2016-03-16 EP disclosed
EP-2994106-A2 CONSUMER PRODUCTS COMPRISING SILANE-MODIFIED OILS The Procter and Gamble Company (US) 2016-03-16 EP disclosed
EP-2994104-A2 CONSUMER PRODUCTS COMPRISING SILANE-MODIFIED OILS The Procter and Gamble Company (US) 2016-03-16 EP disclosed
EP-2994103-A2 CONSUMER PRODUCTS COMPRISING SILANE-MODIFIED OILS The Procter & Gamble Company (US) 2016-03-16 EP disclosed
EP-2994107-A2 CONSUMER PRODUCTS COMPRISING SILANE-MODIFIED OILS The Procter & Gamble Company (US) 2016-03-16 EP disclosed
US-20140335035-A1 Consumer Products Comprising Silane-Modified Oils THE PROCTER & GAMBLE COMPANY (US) 2014-11-13 US disclosed
US-20140335032-A1 Consumer Products Comprising Silane-Modified Oils THE PROCTER & GAMBLE COMPANY (US) 2014-11-13 US disclosed
US-8110036-B2 Moisture curable oil and fat compositions and processes for preparing the same BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERISTY (US) 2012-02-07 US disclosed
WO-2010042175-A1 MOISTURE-CURABLE OIL AND FAT COMPOSITIONS AND PROCESSES FOR PREPARING THE SAME MICHIGAN STATE UNIVERSITY (US) 2010-04-15 WO disclosed
US-20100083871-A1 Moisture-curable oil and fat compositions and processes for preparing the same BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) 2010-04-08 US disclosed
US-4512926-A Process for the silylation of unsaturated, naturally occurring oils or the interesterification products thereof CHEMISCHE WERKE HUELS AG (DE) 1985-04-23 US disclosed
US-4396751-A Homo- and copolymers of 1,3-dienes containing reactive silyl groups, and their preparation and use CHEMISCHE WERKE HUELS AKTIENGESELLSCHAFT (DE) 1983-08-02 US disclosed
US-4381377-A Homo- or copolymers of 1,3-dienes carrying reactive silyl groups, their preparation and use CHEMISCHE WERKE HUELS, AG (DE) 1983-04-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190077815-A1 COMPOSITIONS, SYNTHESIS, AND USES OF HYDROLYZABLE SILANE MODIFIED CASHEW NUT SHELL LIQUID DERIVATIVES NANS, SGMS1, FUT6 GABRA1 4816/4885GABRB2 4867/4885KDM4E 2229/4885
US-20140335035-A1 Consumer Products Comprising Silane-Modified Oils SGMS2, SCD, ELOVL1 GABRA1 3143/4885GABRB2 3005/4885KDM4E 2192/4885
US-10875879-B2 Compositions, synthesis, and uses of hydrolyzable silane modified cashew nut shell liquid derivatives NANS, SGMS1, FUT6 GABRA1 4816/4885GABRB2 4867/4885KDM4E 2229/4885
US-20140335032-A1 Consumer Products Comprising Silane-Modified Oils SGMS2, SGMS1, SCD GABRA1 3297/4885GABRB2 3579/4885KDM4E 2582/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.