SCHEMBL3344788

SCHEMBL3344788

O=C(c1ccccc1)N1CC=CC1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLA2G7 Q13093 2/20 0.61
HPGD P15428 3/20 0.61
SIGMAR1 Q99720 1/20 0.57
ACHE P22303 1/20 0.53
USP2 O75604 1/20 0.53
ALDH1A1 P00352 1/20 0.53
CHRNB2 P17787 1/20 0.52
CHRNB4 P30926 1/20 0.52
CHRNA3 P32297 1/20 0.52
CHRNA7 P36544 1/20 0.52
CHRNA4 P43681 1/20 0.52
BLM P54132 1/20 0.52
MAPK1 P28482 1/20 0.50
MAOB P27338 1/20 0.50
TSHR P16473 1/20 0.50
POLB P06746 1/20 0.49
EPHX1 P07099 1/20 0.49
CA12 O43570 1/20 0.49
CA1 P00915 1/20 0.49
CA2 P00918 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30073083 0.88 PLA2G7 (0.57) PLA2G7HPGDALDH1A1MAPK1POLB
SCHEMBL5391930 0.86 HPGD (0.56) PLA2G7HPGDSIGMAR1ACHEUSP2
SCHEMBL7129676 0.81 HPGD (0.79) HPGDSIGMAR1ACHEUSP2ALDH1A1
SCHEMBL252026 0.81 HPGD (0.79) HPGDSIGMAR1ACHEUSP2ALDH1A1
SCHEMBL9618617 0.81 HPGD (0.65) HPGDSIGMAR1ACHEUSP2ALDH1A1
Hydrochloric Acid SCHEMBL1597472 0.79 HPGD (0.76) HPGDSIGMAR1ACHEUSP2ALDH1A1
SCHEMBL31517025 0.78 PKM (0.66) PLA2G7HPGDUSP2ALDH1A1
SCHEMBL31453519 0.78 PLA2G7 (0.62) PLA2G7ALDH1A1POLBCA12CA1
SCHEMBL3093040 0.78 ALDH1A1 (0.59) PLA2G7HPGDALDH1A1POLBCA12
SCHEMBL31453521 0.78 PLA2G7 (0.62) PLA2G7ALDH1A1POLBCA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119930697-A Benzylidene o-halogenated Ru olefin metathesis catalyst and preparation and application thereof 中国石油天然气股份有限公司 2025-05-06 CN disclosed
WO-2023118267-A1 NOVEL GALACTOSIDE INHIBITOR OF GALECTINS GALECTO BIOTECH AB (DK) 2023-06-29 WO disclosed
CN-115353667-A Method and material for reducing waste 李蓁蓁 2022-11-18 CN disclosed
US-20220219155-A1 Compositions And Methods For Visible-Light-Controlled Ruthenium-Catalyzed Olefin Metathesis THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK 2022-07-14 US disclosed
US-11331656-B2 Compositions and methods for visible-light-controlled ruthenium-catalyzed olefin metathesis THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 2022-05-17 US disclosed
CN-108654695-B Indole [3,2-a ] oxazolidine-labeled ruthenium carbene catalyst, and preparation method and application thereof 天津大学 2021-04-06 CN disclosed
US-10933409-B2 Transition metal complex containing sulfonamide or amide group for olefin metathesis reaction and application thereof SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (KR) 2021-03-02 US disclosed
US-20190030521-A1 TRANSITION METAL COMPLEX CONTAINING SULFONAMIDE OR AMIDE GROUP FOR OLEFIN METATHESIS REACTION AND APPLICATION THEREOF SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (KR) 2019-01-31 US disclosed
US-20180065914-A1 RUTHENIUM POLYMERISATION CATALYSTS UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS (GB) 2018-03-08 US disclosed
US-20180065914-A1 RUTHENIUM POLYMERISATION CATALYSTS UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS (GB) 2018-03-08 US disclosed
EP-0592868-A1 Quinolonecarboxylic acids BAYER AG (DE) 1994-04-20 EP disclosed
EP-0591808-A1 Quinolonecarboxylic acids BAYER AG (DE) 1994-04-13 EP disclosed
EP-0551653-A1 Enantiomeric pure 2-oxa-5,8-diazabicyclo (4.3.0)nonanes and process for their preparation BAYER AG (DE) 1993-07-21 EP disclosed
EP-0550903-A1 Quinolone- and naphthyridone carboxylic acid derivatives as antibacterial agents BAYER AG (DE) 1993-07-14 EP disclosed
CN-1074218-A Quinolone-and naphthyridonecarboxylic acid derivatives BAYER AG (DE) 1993-07-14 CN disclosed
US-5061712-A BACTERICIDES BAYER AKTIENGESELLSCHAFT (DE) 1991-10-29 US disclosed
US-5059597-A Animal growth regulators; enterobacter BAYER AKTIENGESELLSCHAFT (DE) 1991-10-22 US disclosed
US-4990517-A 7-(1-pyrrolidinyl)-3-quinolone- and -naphthyridonecarboxylic acid derivatives as antibacterial agents and feed additives BAYER AKTIENGESELLSCHAFT (DE) 1991-02-05 US disclosed
EP-0401623-A1 Process for the preparation of 7-(3-amino- and 3-aminomethyl-1-pyrrolidinyl)-3-quinolinonecarboxylic and -naphthyridinonecarboxylic acids BAYER AG (DE) 1990-12-12 EP disclosed
EP-0350733-A2 7-(1-Pyrrolidinyl)-3-quinolone- and -naphthyridone-carboxylic-acid derivatives, method for their preparation and for substituted mono- and bi-cyclic pyrrolidine intermediates, and their antibacterial and feed additive compositions BAYER AG (DE) 1990-01-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11331656-B2 Compositions and methods for visible-light-controlled ruthenium-catalyzed olefin metathesis PPOX, CYBA, CYBB PLA2G7 718/4885HPGD 2272/4885SIGMAR1 3642/4885
US-20180065914-A1 RUTHENIUM POLYMERISATION CATALYSTS RRP12, PCBP1, PARG PLA2G7 3749/4885HPGD 1083/4885SIGMAR1 1982/4885
US-10933409-B2 Transition metal complex containing sulfonamide or amide group for olefin metathesis reaction and application thereof TST, NBAS, TRRAP PLA2G7 2611/4885HPGD 3468/4885SIGMAR1 2057/4885
US-20220219155-A1 Compositions And Methods For Visible-Light-Controlled Ruthenium-Catalyzed Olefin Metathesis PPOX, CYBA, CYBB PLA2G7 718/4885HPGD 2272/4885SIGMAR1 3642/4885
US-20190030521-A1 TRANSITION METAL COMPLEX CONTAINING SULFONAMIDE OR AMIDE GROUP FOR OLEFIN METATHESIS REACTION AND APPLICATION THEREOF TST, NIT2, NBAS PLA2G7 1613/4885HPGD 2332/4885SIGMAR1 1569/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.