Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.46 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.37 |
| ▸ | ALKBH3 | Q96Q83 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3346093 | 0.90 | ALDH1A1 (0.46) | ALDH1A1KDM4EHPGDHSD17B10LMNA | |
| SCHEMBL3346540 | 0.87 | ALDH1A1 (0.47) | ALDH1A1KDM4EHPGDHSD17B10TSHR | |
| SCHEMBL3348773 | 0.85 | ALDH1A1 (0.47) | ALDH1A1KDM4EHPGDHSD17B10LMNA | |
| SCHEMBL3345105 | 0.81 | ALDH1A1 (0.45) | ALDH1A1KDM4EHPGDHSD17B10PDE3B | |
| SCHEMBL3347965 | 0.80 | ALDH1A1 (0.48) | ALDH1A1KDM4EHPGDHSD17B10LMNA | |
| SCHEMBL3344690 | 0.79 | SMN1; SMN2 (0.49) | ALDH1A1KDM4EPDE3BPDE3ASMN1; SMN2 | |
| SCHEMBL3345079 | 0.77 | ALDH1A1 (0.42) | ALDH1A1KDM4EHPGDHSD17B10LMNA | |
| SCHEMBL3345539 | 0.77 | ALDH1A1 (0.46) | ALDH1A1KDM4EHPGDHSD17B10LMNA | |
| SCHEMBL3348700 | 0.74 | ALDH1A1 (0.41) | ALDH1A1KDM4EHPGDHSD17B10LMNA | |
| SCHEMBL3344676 | 0.74 | TDP1 (0.44) | ALDH1A1KDM4EHPGDHSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010040989-A1 | QUINOLIN-2-ONE COMPOUNDS | ARGENTA ORAL THERAPEUTICS LIMITED (GB) | 2010-04-15 | — | — | WO | disclosed |