Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | PTGIR | P43119 | 1/20 | 0.33 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 4/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 4/20 | 0.33 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.33 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.33 |
| ▸ | P2RY12 | Q9H244 | 3/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3347965 | 0.83 | ALDH1A1 (0.48) | ALDH1A1KDM4EHPGDHSD17B10MAPT | |
| SCHEMBL3345055 | 0.82 | ALDH1A1 (0.42) | ALDH1A1KDM4EHPGDHSD17B10PDE10A | |
| SCHEMBL3343713 | 0.82 | PDE10A (0.41) | ALDH1A1KDM4EHSD17B10PDE10ATSHR | |
| SCHEMBL3345090 | 0.82 | ALDH1A1 (0.41) | ALDH1A1KDM4EHPGDHSD17B10MAPT | |
| SCHEMBL3346540 | 0.74 | ALDH1A1 (0.47) | ALDH1A1KDM4EHPGDHSD17B10PDE10A | |
| SCHEMBL3351444 | 0.74 | ALDH1A1 (0.47) | ALDH1A1KDM4EHPGDHSD17B10TSHR | |
| SCHEMBL3348773 | 0.74 | ALDH1A1 (0.47) | ALDH1A1KDM4EHPGDHSD17B10TSHR | |
| SCHEMBL3345145 | 0.73 | PTGDR2 (0.41) | ALDH1A1KDM4EHPGDHSD17B10PDE10A | |
| SCHEMBL3346093 | 0.73 | ALDH1A1 (0.46) | ALDH1A1KDM4EHPGDHSD17B10MAPT | |
| SCHEMBL3345539 | 0.70 | ALDH1A1 (0.46) | ALDH1A1KDM4EHPGDHSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010040989-A1 | QUINOLIN-2-ONE COMPOUNDS | ARGENTA ORAL THERAPEUTICS LIMITED (GB) | 2010-04-15 | — | — | WO | disclosed |